Proteasome inhibitors block VCAM-1 and ICAM-1 gene expression in endothelial cells without affecting nuclear translocation of nuclear factor-κB

European Journal of Immunology

Volumn 26, Issue 4, 1996, Pages 839-845

  Cobb, Ronald R ^a   Felts, Katherine A ^a   Parry, Graham C N ^b   Mackman, Nigel ^b  

^a Tanabe Research Laboratories   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Endothelial cell; ICAM 1; Inhibition; Proteasome; VCAM 1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEASOME; PROTEINASE INHIBITOR; TOSYLLYSYL CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; VASCULAR CELL ADHESION MOLECULE 1; ACETYL LEUCINYL LEUCINYL METHIONAL; ACETYL-LEUCINYL-LEUCINYL-METHIONAL; ACETYLLEUCYL LEUCYL NORLEUCINAL; ACETYLLEUCYL-LEUCYL-NORLEUCINAL; CALPAIN; CYSTEINE PROTEINASE; HYBRID PROTEIN; INTERLEUKIN 1; LEUPEPTIN; MESSENGER RNA; MULTIENZYME COMPLEX;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; REPORTER GENE; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; BIOSYNTHESIS; CELL CULTURE; CELL NUCLEUS; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

BASE SEQUENCE; BIOLOGICAL TRANSPORT; CALPAIN; CELL NUCLEUS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; LEUPEPTINS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NF-KAPPA B; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TOSYLLYSINE CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TRANSFECTION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0029664304     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260417     Document Type: Article

References (47)

1. Springer, T. A., Cell 1994. 76: 301.
2. Collins, T., Read, M.A., Neish, A.S., Whitley, M.Z., Thanos, D. and Maniatis, T., FASEB J. 1995. 9: 899.
3. Dustin, M. L., Rothiein, R., Bhan, A. K., Dinarello, C. A. and Springer, T. A., J. Immunol. 1986. 137: 245.
4. Pober, J. S., Bevilaqua, M. P., Mendrick, D. L., Lapierre, L. A., Fiers, W. and Gimbrone, M. A., J. Immunol. 1986. 136: 1680.
5. Rothlein R., Czajkowski, M., O'Neill, M M., Marlin, S. D., Mainolfi, E. and Merluzzi, V. J., J. Immunol. 1988. 141: 1665.
6. Osborn, L., Hession, C., Tizard, R., Vassallo, C., Luhowskyj, S., Chi-Rosso, G. and Lobb, R., Cell 1989. 59: 1203.
7. Elices, M. J., Osborn, L., Takada, Y., Crouse, C., Luhowskyj, S., Hemler, M. E. and Lobb, R., Cell 1990. 60: 577.
8. Montgomery, K. F., Osborn, L., Hession, C., Tizard, R., Goff, D., Vassallo, C., Tarr, P. I., Bomsztyk, K., Lobb, R., Harlan, J. H. and Pohlman, T. H., Proc. Natl. Acad, Sci. USA 1991. 88: 6523.
9. Voraberger, G., Schafer, R. and Stratowa, C. J. Immunol. 1991. 147: 2777.
10. van de Stolpe, A., Caldenhoven, E., Stade, B. G., Koenderman, L., Raaijmakers, J. A. M., Johnson, J. P. and van der Saag, P. T., J. Biol. Chem. 1994, 269: 6185.
11. Iademarco, M. F., McQuillan, J. J., Rosen, G. D. and Dean, D. C., J. Biol. Chem. 1992. 267: 16323.
12. Neish, A. S., Williams, A. J., Palmer, H. J., Whitley, M. Z. and Collis, T., J. Exp. Med. 1992. 776: 1583.
13. Ghersa, P., van Huijsduijnen, R. H., Whelan, J. and DeLamarter, J. F., J. Biol. Chem. 1992. 267: 19226.
14. Lenardo, M. J. and Baltimore, D., Cell 1989. 58: 227.
15. Kawakami, K., Scheidereit, C. and Roeder, R. G., Proc. Natl. Acad. Sci. USA 1988. 85: 4700.
16. Lenardo, M. J., Kuang, A., Gifford, A. and Baltimore, D., Proc. Natl. Acad. Sci. USA 1988. 85: 8825.
17. Baeuerle, P. and Baltimore, D., Science 1988. 242: 540.
18. Beg, A. A., Finco, T. S., Nantermet, P. V. and Baldwin, A. S. Jr., Mol. Cell. Biol. 1993. 13: 3301.
19. Brown, K., Park, S., Kanno, T., Franzoso, G. and Siebenlist. U., Proc. Natl. Acad. Sci. USA 1993. 90: 2532.
20. Henkel, T., Machleidt, T., Alkaly, I., Kronke, M., Ben-Neriah, Y. and Baeuerle, P. A., Nature 1993. 365: 182.
21. Sun, S.-C., Ganchi, P. A., Ballard, D. W. and Greene, W. C., Science 1993. 259: 1912.
22. Traenckner, E. B.-M., Wilk, S. and Baeuerle, P.A., EMBO J. 1994. 13: 5433.
23. Finco, T. S., Beg, A. A. and Baldwin, A. S. Jr., Proc. Natl. Acad. Sci. USA 1994. 91: 11884.
24. Palombella, V. J., Rando, O. J., Goldberg, A. L. and Maniatis, T., Cell 1994. 78: 773.
25. Fan, C.-M. and Maniatis, T., Nature 1991. 354: 395.
26. Shu, H. B., Agranoff, A. B., Nabel, E. G., Leung, K., Duckett, C. S., Neish, A. S., Collins, T. and Nabel, G. J., Mol. Cell. Biol. 1993. 13: 6283.
27. Parry, G. C. N. and Mackman, N., J. Biol. Chem. 1994. 269: 20823.
28. Ledebur, H. C. and Parks, T. P., J. Biol. Chem. 1995. 270: 933.
29. Hou, J., Baichwal, V. and Cao, Z., Proc. Natl. Acad. Sci. USA 1994. 91: 11641.
30. Read, M. A., Whitley, M. Z., Williams, A. J. and Collins, T., J. Exp. Med. 1994. 179: 503.
31. Goldberg, A. L. Eur. J. Biochem. 1992. 203: 9.
32. Hershko, A. and Ciechanover, A., Annu. Rev. Biochem. 1992. 61: 761.
33. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D. and Goldberg, A. L., Cell 1994. 78: 761.
34. Cobb, R. R., Martin, J., Korytynski, E., Monteith, L. and Hughes, T. J., Mutat. Res. 1989. 226: 253.
35. Maniatis, T., Fritsch, E. F. and Sambrook, J. (Eds.), Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory. Cold Spring Harbor 1982.
36. Parry, G. C. N., Mackman, N., Arterioscler. Thromb. Vasc. Biol. 1995. 115: 612.
37. Read, M. A., Cordle, S. R., Veach, R. A., Carlisle, C. D. and Hawiger, J., Proc. Natl. Acad. Sci. USA 1993. 90: 9887.
38. Oeth, P. A., Parry, G. C. N., Kunsch, C., Nantermet, P., Rosen, C. A. and Mackman, N., Mol. Cell. Biol. 1994. 14: 3772.
39. Visnitsky, A., Michaud, C., Powers, J. J. and Orlowski, M., Biochemistry 1992. 31: 9421.
40. McGowan, E. B., Backer, E. and Detwiler, T. C., Biochem. Biophys. Res. Commun. 1989. 158: 432.
41. Barrett, A. J., Kembhavi, A. A., Brown, M. A., Kirschke, H., Knight, C. G., Tamai, M. and Hanada, K., Biochem J. 1982. 201: 189.
42. Deescheemaeker, K. A., Wyns, S., Nelles, L., Auwerx, J., Ny, T. and Collen, D., J. Biol. Chem. 1992. 267: 15086.
43. Chiao, P. J., Miyamoto, S. and Verma, I., Proc. Natl. Acad. Sci. USA 1994. 91: 28.
44. Marui, N., Offermann, M. K., Swerlick, R., Kunsch, C., Rosen, C.A., Ahmad, M., Alexander, R. W., Medford, R. M., J. Clin. Invest. 1993. 92:1866.
45. Read, M. A., Neish, A. S., Luscinskas, F. W., Palombella, V. J., Maniatis, T., Collins. C., Immunity 1995. 2:493.
46. Ghersa, P., van Huijsduihnen, R. H., Whelan, J., Cambet, Y., Pescini, R. and DeLamarter, J. F., J. Biol. Chem. 1994. 269: 29129.
47. Neish, A. S., Read, M. A., Thanos, D., Pine, R., Maniatis, T. and Collins, T., Mol. Cell. Biol. 1995. 75: 2558.