Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice

Journal of Neuroimmunology

Volumn 114, Issue 1-2, 2001, Pages 69-79

  Du, Caigan ^a   Bright, John J ^a   Sriram, Subramanian ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

CD40; EAE; IL 12; Tyrphostin

Indexed keywords

CD40 ANTIGEN; CYTOKINE; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; MYELIN BASIC PROTEIN; TYRPHOSTIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; FEMALE; GENE ACTIVATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL;

ANIMALS; ANTIGENS, CD40; AUTOANTIGENS; CD40 LIGAND; CELL DIVISION; CELL NUCLEUS; CELLS, CULTURED; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION; INTERFERON TYPE II; INTERLEUKIN-12; LYMPH NODES; MACROPHAGES; MICE; MICE, INBRED STRAINS; MYELIN BASIC PROTEINS; NF-KAPPA B; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; SOLUBILITY; TH1 CELLS; TYRPHOSTINS;

EID: 0035283231     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00434-3     Document Type: Article

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