-
1
-
-
0031626414
-
CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction
-
BLAIR P. J., RILEY J. L., LEVINE B. L., LEE K. P., CRAIGHEAD N., FRANCOMANO T., PERFETTO S. J., GRAY G. S., CARRENO B. M. and JUNE C. H. (1998): CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction. J. Immunol., 160, 12-15.
-
(1998)
J. Immunol.
, vol.160
, pp. 12-15
-
-
Blair, P.J.1
Riley, J.L.2
Levine, B.L.3
Lee, K.P.4
Craighead, N.5
Francomano, T.6
Perfetto, S.J.7
Gray, G.S.8
Carreno, B.M.9
June, C.H.10
-
2
-
-
0031091743
-
Is CTLA-4 a master switch for peripheral T cell tolerance?
-
BLUESTONE J. A. (1997): Is CTLA-4 a master switch for peripheral T cell tolerance? J. Immunol., 158, 1989-1993.
-
(1997)
J. Immunol.
, vol.158
, pp. 1989-1993
-
-
Bluestone, J.A.1
-
3
-
-
0031471027
-
Interaction of the cytoplasmic tail of CTLA-4 (CD 152) with a clathrin-associated protein is negatively regulated by tyrosine phosphorylation
-
BRADSHAW J., LU P., LEYTZE G., RODGERS J., SCHIEVEN G. L., BENNETT K. L., LINSLEY P. S. and KURTZ S. E. (1997): Interaction of the cytoplasmic tail of CTLA-4 (CD 152) with a clathrin-associated protein is negatively regulated by tyrosine phosphorylation. Biochemistry, 36, 15975-15982.
-
(1997)
Biochemistry
, vol.36
, pp. 15975-15982
-
-
Bradshaw, J.1
Lu, P.2
Leytze, G.3
Rodgers, J.4
Schieven, G.L.5
Bennett, K.L.6
Linsley, P.S.7
Kurtz, S.E.8
-
4
-
-
0023820250
-
A differential molecular biology search for genes preferentially expressed in functional T lymphocytes: The CTLA-4 genes
-
BRUNET J. F., DENIZOT F. and GOLSTEIN P. (1988): A differential molecular biology search for genes preferentially expressed in functional T lymphocytes: the CTLA-4 genes. Immunol. Rev., 103, 21-36.
-
(1988)
Immunol. Rev.
, vol.103
, pp. 21-36
-
-
Brunet, J.F.1
Denizot, F.2
Golstein, P.3
-
5
-
-
0023270567
-
A new member of the immunoglobulin superfamily - CTLA-4
-
BRUNET J. F., DENIZOT F., LUCIANI M-F., ROUX-DOSSETO M., SUZAN M., MATTEI M.-G and GOLSTEIN P. (1987): A new member of the immunoglobulin superfamily - CTLA-4. Nature, 328, 267-270.
-
(1987)
Nature
, vol.328
, pp. 267-270
-
-
Brunet, J.F.1
Denizot, F.2
Luciani, M.-F.3
Roux-Dosseto, M.4
Suzan, M.5
Mattei, M.-G.6
Golstein, P.7
-
6
-
-
0030707866
-
Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP-70
-
CALVO C. R., ANUSEN D. and KRUISBEEK A. M. (1997): Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP-70. J. Exp. Med., 186, 1645-1653.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1645-1653
-
-
Calvo, C.R.1
Anusen, D.2
Kruisbeek, A.M.3
-
7
-
-
0029800932
-
The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signaling
-
CHAMBERS C. A. and ALLISON J. P. (1996): The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signaling. Eur. J. Immunol., 26, 3224-3229.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 3224-3229
-
-
Chambers, C.A.1
Allison, J.P.2
-
8
-
-
0030740248
-
Thymocyte development is normal in CTLA-4-deficient mice
-
CHAMBERS C. A., CADO D., TRUONG T. and ALLISON J. P. (1997): Thymocyte development is normal in CTLA-4-deficient mice. Proc. Natl. Acad. Sci. USA, 94, 9296-9301.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9296-9301
-
-
Chambers, C.A.1
Cado, D.2
Truong, T.3
Allison, J.P.4
-
9
-
-
0030300139
-
The role of CTLA-4 in the regulation and initiation of T cell responses
-
CHAMBERS C. A., KRUMMEL M. F., BOITEL B., HURWITZ A. A., SULIVA T. J., FOURNIER S., CARSELL D., BRUNNER M. and ALLISON J. P. (1996): The role of CTLA-4 in the regulation and initiation of T cell responses. Immunol. Rev., 153, 27-46.
-
(1996)
Immunol. Rev.
, vol.153
, pp. 27-46
-
-
Chambers, C.A.1
Krummel, M.F.2
Boitel, B.3
Hurwitz, A.A.4
Suliva, T.J.5
Fournier, S.6
Carsell, D.7
Brunner, M.8
Allison, J.P.9
-
10
-
-
0031181647
-
Interaction of CTLA-4 with the clathrin-assiciated protein AP-50 results in ligand-independent endocytosis that limits cell surface expression
-
CHUANG E., ALEGRE M. L., DUCKETT C. S., NOEL P. J., VANDER-HEIDEN M. G. and THOMPSON C. B. (1997): Interaction of CTLA-4 with the clathrin-assiciated protein AP-50 results in ligand-independent endocytosis that limits cell surface expression. J. Immunol., 159, 144-151.
-
(1997)
J. Immunol.
, vol.159
, pp. 144-151
-
-
Chuang, E.1
Alegre, M.L.2
Duckett, C.S.3
Noel, P.J.4
Vander-Heiden, M.G.5
Thompson, C.B.6
-
11
-
-
0028215960
-
Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7
-
DAMLE N. K., KLUSSMAN K., LEYTZE G., MYRDAL S., ANUFFO A., LEDBETTER J. A. and LINSLEY P. S. (1994): Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7. J. Immunol., 152, 2686-2697.
-
(1994)
J. Immunol.
, vol.152
, pp. 2686-2697
-
-
Damle, N.K.1
Klussman, K.2
Leytze, G.3
Myrdal, S.4
Anuffo, A.5
Ledbetter, J.A.6
Linsley, P.S.7
-
12
-
-
0024205313
-
Human Ig superfamily. CTLA-4 gene: Chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains
-
DARIAVACH P., MATTEI M.-G., GOLSTEIN P. and LEFRANC M.-P. (1988): Human Ig superfamily. CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. Eur. J. Immunol 18, 1901-1905.
-
(1988)
Eur. J. Immunol
, vol.18
, pp. 1901-1905
-
-
Dariavach, P.1
Mattei, M.-G.2
Golstein, P.3
Lefranc, M.-P.4
-
13
-
-
0031766135
-
Unresponsive CD4+ T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockade of B7/CTLA-4 molecular pathway
-
GOMES N. A., BARRETO-DE-SOUZA V., WILSON M. E. and DOSREIS G. A. (1998): Unresponsive CD4+ T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockade of B7/CTLA-4 molecular pathway. J. Infect. Dis., 178, 1847-1851.
-
(1998)
J. Infect. Dis.
, vol.178
, pp. 1847-1851
-
-
Gomes, N.A.1
Barreto-De-Souza, V.2
Wilson, M.E.3
Dosreis, G.A.4
-
14
-
-
0028870051
-
CTLA-4 mediates antigen-specific apoptosis of human T-cells
-
GRIBBEN J. G., FREEMAN G. J., BOUSIOTTIS V. A., RENNERT P., JELLIS C. L., GREENFIELD E., BARBER M., RESTIVO V. A., KE X., GRAY G. S. and NADLER L. M. (1995): CTLA-4 mediates antigen-specific apoptosis of human T-cells. Proc. Natl. Acad. Aci. USA, 92, 811-815.
-
(1995)
Proc. Natl. Acad. Aci. USA
, vol.92
, pp. 811-815
-
-
Gribben, J.G.1
Freeman, G.J.2
Bousiottis, V.A.3
Rennert, P.4
Jellis, C.L.5
Greenfield, E.6
Barber, M.7
Restivo, V.A.8
Ke, X.9
Gray, G.S.10
Nadler, L.M.11
-
15
-
-
0025735829
-
CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location
-
HARPER K., BALZANO C., ROUVIER E., MATTEI M. G., LUCIANI M. F. and GOLSTEIN P. (1991): CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J. Immunol., 147, 1037-1044.
-
(1991)
J. Immunol.
, vol.147
, pp. 1037-1044
-
-
Harper, K.1
Balzano, C.2
Rouvier, E.3
Mattei, M.G.4
Luciani, M.F.5
Golstein, P.6
-
16
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
HUNTER T. (1995): Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell, 80, 225-236.
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
17
-
-
0031047696
-
Specific blockade of CTLA-4/B7 interactions results in exacebated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis
-
HURWITZ A. A., SULLIVAN T. J., KRUMMEL M. F., SOBEL R. A. and ALLISON J. P. (1997): Specific blockade of CTLA-4/B7 interactions results in exacebated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. J. Neuroimmunol., 73, 57-62.
-
(1997)
J. Neuroimmunol.
, vol.73
, pp. 57-62
-
-
Hurwitz, A.A.1
Sullivan, T.J.2
Krummel, M.F.3
Sobel, R.A.4
Allison, J.P.5
-
18
-
-
0032544067
-
CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
-
HURWITZ A. A., YU T. F., LEACH D. R. and ALLISON J. P. (1998): CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma. Proc. Natl. Acad. Sci USA, 95, 10067-10071.
-
(1998)
Proc. Natl. Acad. Sci USA
, vol.95
, pp. 10067-10071
-
-
Hurwitz, A.A.1
Yu, T.F.2
Leach, D.R.3
Allison, J.P.4
-
19
-
-
0028501442
-
The ups and downs of costimulation
-
JENKINS M. K. (1994): The ups and downs of costimulation. Immunity, 1, 443-446.
-
(1994)
Immunity
, vol.1
, pp. 443-446
-
-
Jenkins, M.K.1
-
20
-
-
0029789389
-
CTLA-4, a negative regulator of autoimmune disease
-
KARANDIKAR N. J., VANDERLUGT C. L., WALUNAS T. L., MILLER S. D. and BLUESTONE J. A. (1996): CTLA-4, a negative regulator of autoimmune disease. J. Exp. Med., 184, 783-788.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 783-788
-
-
Karandikar, N.J.1
Vanderlugt, C.L.2
Walunas, T.L.3
Miller, S.D.4
Bluestone, J.A.5
-
21
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
KRUMMEL M. F. and ALLISON J. P. (1995): CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med., 182, 459-465.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
22
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
KRUMMEL M. F. and ALLISON J. P. (1996): CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med., 183, 2533-2540.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
23
-
-
0029960141
-
Superantigen responses and costimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo
-
KRUMMEL M. F., SULLIVAN T. J. and ALLISON J. P. (1996): Superantigen responses and costimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo. Int. Immunol., 8, 519-523.
-
(1996)
Int. Immunol.
, vol.8
, pp. 519-523
-
-
Krummel, M.F.1
Sullivan, T.J.2
Allison, J.P.3
-
24
-
-
0030743846
-
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
-
KWON E. D., HURWITZ A. A., FOSTER B. A., MADIAS C., FELDHAUS A. L., GREENBERG N. M., BURG M. B. and ALLISON J. P. (1997): Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer. Proc. Natl. Acad. Sci. USA, 94, 8099-8103.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8099-8103
-
-
Kwon, E.D.1
Hurwitz, A.A.2
Foster, B.A.3
Madias, C.4
Feldhaus, A.L.5
Greenberg, N.M.6
Burg, M.B.7
Allison, J.P.8
-
25
-
-
0025217670
-
Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34
-
LAFAGE-POCHITALOFF M. R., COSTELLO D., COUEZ J., SIMONETTI D., MANNONI C., MAWAS C. and OLIVE D. (1990): Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34. Immunogenetics, 31, 198-201.
-
(1990)
Immunogenetics
, vol.31
, pp. 198-201
-
-
Lafage-Pochitaloff, M.R.1
Costello, D.2
Couez, J.3
Simonetti, D.4
Mannoni, C.5
Mawas, C.6
Olive, D.7
-
26
-
-
0029947568
-
Enchancement of antitumor immunity by CTLA-4 blockade
-
LEACH D. R., KRUMMEL M. F. and ALLISON J. P. (1996): Enchancement of antitumor immunity by CTLA-4 blockade. Science, 271, 1734-1736.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
28
-
-
0028852073
-
Cytotoxic T lymphocyte-associated molecule-4, a high avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail
-
LEUNG H. T., BRADSHAW J., CLEAVELAND J. S. and LINSLEY P. S. (1995): Cytotoxic T lymphocyte-associated molecule-4, a high avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail. J. Biol. Chem., 270, 1-8.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1-8
-
-
Leung, H.T.1
Bradshaw, J.2
Cleaveland, J.S.3
Linsley, P.S.4
-
29
-
-
0027282960
-
Characterization of CTLA-4 structure and expression on human T-cells
-
LINDSTEN T., LEE K. P., HARRIS E. S., PETRYNIAK B., CRAIGHEAD N., REYNOLDS P. J., LOMBARD D. B., FREEMAN G. J., NADLER L. M., GRAY G. S., THOMPSON C. B. and JUNE C. H. (1993): Characterization of CTLA-4 structure and expression on human T-cells. J. Immunol., 151, 3489-3499.
-
(1993)
J. Immunol.
, vol.151
, pp. 3489-3499
-
-
Lindsten, T.1
Lee, K.P.2
Harris, E.S.3
Petryniak, B.4
Craighead, N.5
Reynolds, P.J.6
Lombard, D.B.7
Freeman, G.J.8
Nadler, L.M.9
Gray, G.S.10
Thompson, C.B.11
June, C.H.12
-
30
-
-
0030176371
-
Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
-
LINSLEY P. S., BRADSHAW J., GREENE J., PEACH R., BENNET K. L. and MITTLER R. S. (1996): Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity, 4, 535-543.
-
(1996)
Immunity
, vol.4
, pp. 535-543
-
-
Linsley, P.S.1
Bradshaw, J.2
Greene, J.3
Peach, R.4
Bennet, K.L.5
Mittler, R.S.6
-
31
-
-
0028675006
-
Human B. 7-1 (CD80) and B. 7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
-
LINSLEY P. S., GREENE J. L., BRADY W., BAJORATH J., LEDBETTER J. A. and PEACH R. (1994): Human B. 7-1 (CD80) and B. 7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity, 1, 793-801.
-
(1994)
Immunity
, vol.1
, pp. 793-801
-
-
Linsley, P.S.1
Greene, J.L.2
Brady, W.3
Bajorath, J.4
Ledbetter, J.A.5
Peach, R.6
-
32
-
-
0026486220
-
Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes
-
LINSLEY P. S., GREENE J. L., TAN P., BRADSCHAW J., LEDBETTER J. A., ANASETTI C. and DAMLE N. K. (1992): Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes. J. Exp. Med., 176, 1595-1604.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1595-1604
-
-
Linsley, P.S.1
Greene, J.L.2
Tan, P.3
Bradschaw, J.4
Ledbetter, J.A.5
Anasetti, C.6
Damle, N.K.7
-
33
-
-
0027403299
-
The role of the CD28 receptor during T cell responses to antigen
-
LINSLEY P. S. and LEDBETTER J. A. (1993): The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol., 11, 191-212.
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 191-212
-
-
Linsley, P.S.1
Ledbetter, J.A.2
-
34
-
-
0029031518
-
Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4)
-
LINSLEY P. S., NADLER S. G., BAJORATH J., PEACH R., LEUNG H. T., ROGERS J., BRADSHAW J., STEBBINS M., LEYTZE G. and BRADY W. (1995): Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). J. Biol. Chem., 270, 15417-15424.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15417-15424
-
-
Linsley, P.S.1
Nadler, S.G.2
Bajorath, J.3
Peach, R.4
Leung, H.T.5
Rogers, J.6
Bradshaw, J.7
Stebbins, M.8
Leytze, G.9
Brady, W.10
-
35
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine-phosphatase Syp association with CTLA-4
-
MARENGERE L. E. M., WATERHOUSE P., DUNCAN G. S., MITTRUCKER H.-W., FENG G. S. and MAK T. W. (1996): Regulation of T cell receptor signaling by tyrosine-phosphatase Syp association with CTLA-4. Science, 272, 1170-1173.
-
(1996)
Science
, vol.272
, pp. 1170-1173
-
-
Marengere, L.E.M.1
Waterhouse, P.2
Duncan, G.S.3
Mittrucker, H.-W.4
Feng, G.S.5
Mak, T.W.6
-
36
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
MARSHAL C. J. (1995): Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell, 80, 179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshal, C.J.1
-
37
-
-
0030872154
-
Protective immunity to nematode infection is induced by CTLA-4 blockade
-
MCCOY K., CAMBIRES M. and GROS G. L. (1997): Protective immunity to nematode infection is induced by CTLA-4 blockade. J. Exp. Med., 186, 183-187.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 183-187
-
-
McCoy, K.1
Cambires, M.2
Gros, G.L.3
-
38
-
-
0032547259
-
Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152)
-
MIYATAKE S., NAKASEKO C., UMEMORI H., YAMAMOTO T. and SAITO T. (1998): Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152). Biochem. Biophys. Res. Commun., 249, 444-448.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.249
, pp. 444-448
-
-
Miyatake, S.1
Nakaseko, C.2
Umemori, H.3
Yamamoto, T.4
Saito, T.5
-
39
-
-
0030030181
-
Differential effects of CTLA-4 substitutions on the binding of human CD80 (B. 7-1) and CD86 (B. 7-2)
-
MORTON P. A., FU X-T., STEWART J. A., GIACOLETTO K. S., WHITE S. L., LEYSATH S. E., EVANS R. J., SHIEH J.-J. and KARR R. W. (1996): Differential effects of CTLA-4 substitutions on the binding of human CD80 (B. 7-1) and CD86 (B. 7-2). J. Immunol., 156, 1047-1054.
-
(1996)
J. Immunol.
, vol.156
, pp. 1047-1054
-
-
Morton, P.A.1
Fu, X.-T.2
Stewart, J.A.3
Giacoletto, K.S.4
White, S.L.5
Leysath, S.E.6
Evans, R.J.7
Shieh, J.-J.8
Karr, R.W.9
-
40
-
-
0028859279
-
Protein modules and signalling networks
-
PAWSON T. (1995): Protein modules and signalling networks. Nature, 373, 573-580.
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
41
-
-
0027937702
-
Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine binding to B. 7-1
-
PEACH R. J., BAJORATH J., BRADY W., LEYTZE G., GREENE J., NAEMURA J. and LINSLEY P. S. (1994): Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine binding to B. 7-1. J. Exp. Med., 180, 2049-2058.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2049-2058
-
-
Peach, R.J.1
Bajorath, J.2
Brady, W.3
Leytze, G.4
Greene, J.5
Naemura, J.6
Linsley, P.S.7
-
42
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagements
-
PEREZ V. L., VAN PARUS L., BIUCKIANS A., ZHENG X. X., STROM T. B. and ABBAS A. K. (1997): Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagements. Immunity, 6, 411-417.
-
(1997)
Immunity
, vol.6
, pp. 411-417
-
-
Perez, V.L.1
Van Parus, L.2
Biuckians, A.3
Zheng, X.X.4
Strom, T.B.5
Abbas, A.K.6
-
43
-
-
15844380367
-
Regulation of CTLA-4 expression during T cell activation
-
PERKINS D., NANG Z., DONOVAN C., HE H., MARK D., GUAN G., WANG Y., WALUNAS T., BLUESTONE J. and LISTMAN J. (1996): Regulation of CTLA-4 expression during T cell activation. J. Immunol., 156, 4154-4159.
-
(1996)
J. Immunol.
, vol.156
, pp. 4154-4159
-
-
Perkins, D.1
Nang, Z.2
Donovan, C.3
He, H.4
Mark, D.5
Guan, G.6
Wang, Y.7
Walunas, T.8
Bluestone, J.9
Listman, J.10
-
44
-
-
0031944923
-
CTLA-4 is required for the induction of high dose oral tolerance
-
SAMOILOVA E. B., HORTON J. L., ZHANG H., KHOURY S. J., WEINER H. L. and CHEN Y. (1998): CTLA-4 is required for the induction of high dose oral tolerance. Int. Immunol., 10, 491-498.
-
(1998)
Int. Immunol.
, vol.10
, pp. 491-498
-
-
Samoilova, E.B.1
Horton, J.L.2
Zhang, H.3
Khoury, S.J.4
Weiner, H.L.5
Chen, Y.6
-
45
-
-
0032543987
-
Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 cross-linking
-
SCHEIPERS P. and REISER H. (1998): Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 cross-linking. Proc. Natl. Acad. Sci. USA, 95, 10083-10088.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10083-10088
-
-
Scheipers, P.1
Reiser, H.2
-
46
-
-
0030917081
-
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
-
SHIRATORI T., MIYATAKE S., OHNO H., NAKASEKO C., ISONO K., BONIFACINO J. S. and SAITO T. (1997): Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. Immunity, 6, 583-589.
-
(1997)
Immunity
, vol.6
, pp. 583-589
-
-
Shiratori, T.1
Miyatake, S.2
Ohno, H.3
Nakaseko, C.4
Isono, K.5
Bonifacino, J.S.6
Saito, T.7
-
47
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
SONGYANG Z., SHOELSON S. E., CHAUDHURI M., GISH G., PAWSON T., NASER W. G., KING F., ROBERTS T., RATNOFSKY S., LECHLEIDER R. J., NEEL B. G., BIRGE R. B., FAJARDO J. E., CHOU M. M., HANAFUSA H., SCHAFFHAUSEN B. and CANTLEY L. C. (1993): SH2 domains recognize specific phosphopeptide sequences. Cell, 72, 767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Naser, W.G.6
King, F.7
Roberts, T.8
Ratnofsky, S.9
Lechleider, R.J.10
Neel, B.G.11
Birge, R.B.12
Fajardo, J.E.13
Chou, M.M.14
Hanafusa, H.15
Schaffhausen, B.16
Cantley, L.C.17
-
48
-
-
0028291525
-
JNK is involved in signal integration during costimulation of T lymphocytes
-
SU B., JACINTO E., HIBI M., KALLUNKI T., KARIN M. and BEN-NERIACH Y. (1994): JNK is involved in signal integration during costimulation of T lymphocytes. Cell, 77, 727-736.
-
(1994)
Cell
, vol.77
, pp. 727-736
-
-
Su, B.1
Jacinto, E.2
Hibi, M.3
Kallunki, T.4
Karin, M.5
Ben-Neriach, Y.6
-
49
-
-
0031154577
-
CTLA-4 Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
-
TIVOL E. A., BOYD S. D., MCKEON S., BORRIELLO F., NICKERSON P., STROM T. B. and SHARPE A. H. (1997): CTLA-4 Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J. Immunol., 158, 5091-5094.
-
(1997)
J. Immunol.
, vol.158
, pp. 5091-5094
-
-
Tivol, E.A.1
Boyd, S.D.2
McKeon, S.3
Borriello, F.4
Nickerson, P.5
Strom, T.B.6
Sharpe, A.H.7
-
50
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
WALUNAS T. L., BAKKER C. Y. and BLUESTONE J. A. (1996): CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med., 183, 2541-2550.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
51
-
-
0032522488
-
CTLA-4 regulates tolerance induction and T cell differentiation in vivo
-
WALUNAS T. L. and BLUESTONE J. A. (1998): CTLA-4 regulates tolerance induction and T cell differentiation in vivo. J. Immunol., 160, 3855-3860.
-
(1998)
J. Immunol.
, vol.160
, pp. 3855-3860
-
-
Walunas, T.L.1
Bluestone, J.A.2
-
52
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
WALUNAS T. L., LENSHOW D. J., BAKKER C. Y., LINSLEY P. S., FREEMAN G. J., GREEN J. M., THOMPSON C. B. and BLUESTONE J. A. (1994): CTLA-4 can function as a negative regulator of T cell activation, Immunity, 1, 405-413.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenshow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
53
-
-
0030300146
-
CTLA-4, a negative regulator of T lymphocyte activation
-
WATERHOUSE P., MARENGERE L. E. M., MITTRUCKER H. W. and MAK T. W. (1996): CTLA-4, a negative regulator of T lymphocyte activation. Immunol. Rev., 153, 183-207.
-
(1996)
Immunol. Rev.
, vol.153
, pp. 183-207
-
-
Waterhouse, P.1
Marengere, L.E.M.2
Mittrucker, H.W.3
Mak, T.W.4
-
54
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
WATERHOUSE P., PENNINGER J. M., TIMMS E., WAKEHAM A., SHAHINIAN A., LEE K. P., THOMPSON C. B., GRIESSER H. and MAK T. W. (1995): Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science, 270, 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
55
-
-
0030853610
-
Enhanced induction of antitumor T-cell responses by cytotoxic T-lymphocyte-associated molecule-4 blockade: The effect is manifested only at the restricted tumor-bearing stages
-
YANG Y. F., ZOU J. P., MU J., WIJESURIYA R., ONO S., WALUNAS T., BLUESTONE J., FUJIWARA H. and HAMAOKA T. (1997): Enhanced induction of antitumor T-cell responses by cytotoxic T-lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer Res., 57, 4036-4041.
-
(1997)
Cancer Res.
, vol.57
, pp. 4036-4041
-
-
Yang, Y.F.1
Zou, J.P.2
Mu, J.3
Wijesuriya, R.4
Ono, S.5
Walunas, T.6
Bluestone, J.7
Fujiwara, H.8
Hamaoka, T.9
-
56
-
-
0030611358
-
Interaction of CTLA-4 with AP-50, a clathrin-coated pit adaptor protein
-
ZHANG Y. and ALLISON J. P. (1997): Interaction of CTLA-4 with AP-50, a clathrin-coated pit adaptor protein. Proc. Natl. Acad. Sci. USA, 94, 9273-9278.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9273-9278
-
-
Zhang, Y.1
Allison, J.P.2
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