Cutting edge: CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows bcl-X(L) induction

Journal of Immunology

Volumn 160, Issue 1, 1998, Pages 12-15

  Blair, Patrick J ^a   Riley, James L ^b   Levine, Bruce L ^c   Lee, Kelvin P ^a   Craighead, Nancy ^a   Francomano, Tara ^c   Perfetto, Steven J ^c   Gray, Gary S ^d   Carreno, Beatriz M ^d   June, Carl H ^a,c  

^a NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DNA; INTERLEUKIN 2; MONOCLONAL ANTIBODY; RNA; ABATACEPT; ANTIBODY CONJUGATE; BCL2L1 PROTEIN, HUMAN; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; MESSENGER RNA; PROTEIN BCL 2; PROTEIN BCL X;

ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL CYCLE; GENETICS; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BCL-X PROTEIN; CD4-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELLS, CULTURED; GENE EXPRESSION; HUMANS; IMMUNOCONJUGATES; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0031626414     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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