Inhibition of acetylcholine-activated K+ currents by U73122 is mediated by the inhibition of PIP2-channel interaction

British Journal of Pharmacology

Volumn 134, Issue 5, 2001, Pages 1066-1072

  Cho, Hana ^a   Youm, Jae Boum ^b   Ryu, Shin Young ^a   Earm, Yung E ^a   Ho, Won Kyung ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

Author keywords

Atrial myocytes; Patch clamp; Phosphatidylinositol 4,5 bisphosphate; Phospholipase C; Phospholipase C inhibitor; U73122; U73343

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; ACETYLCHOLINE; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C INHIBITOR; POTASSIUM CHANNEL; SODIUM ION;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; HEART ATRIUM; HEART MUSCLE CELL; MOUSE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; STEADY STATE;

EID: 0035173468     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704347     Document Type: Article

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