Nonselective effects of the putative phospholipase C inhibitor, U73122, on adenosine A1 receptor-mediated signal transduction events in Chinese hamster ovary cells

Biochemical Pharmacology

Volumn 56, Issue 11, 1998, Pages 1455-1462

  Walker, Elizabeth M ^a   Bispham, Jayson R ^a   Hill, Stephen J ^a  

^a Medical School   (United Kingdom)

Author keywords

Adenosine A1 receptors; Adenylyl cyclase; CHO K1 cells; Phospholipase C; U73122; U73343

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; ADENOSINE A1 RECEPTOR; CYCLIC AMP; FORSKOLIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INOSITOL PHOSPHATE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; CYTOLYSIS; DOSE RESPONSE; DRUG SELECTIVITY; HYDROLYSIS; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; CHO CELLS; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESTRENES; FORSKOLIN; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INOSITOL PHOSPHATES; KINETICS; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; PYRROLIDINONES; RECEPTORS, PURINERGIC P1; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; XANTHINES;

EID: 0031795587     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00256-1     Document Type: Article

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