TNFα and IFNγ induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression

Molecular Therapy

Volumn 3, Issue 5, 2001, Pages 757-767

  Sung, Randall S ^a   Qin, Lihui ^a   Bromberg, Jonathan S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Gene therapy; Infectious immunity virus

Indexed keywords

BETA GALACTOSIDASE; GAMMA INTERFERON; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE TRANSFER; HUMAN CYTOMEGALOVIRUS; IMMUNE RESPONSE; IMMUNITY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PROMOTER REGION; REPORTER GENE; TRANSGENE; VIRUS GENE; VIRUS INFECTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CBA MOUSE; CELL DIVISION; CYTOMEGALOVIRUS; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE VECTOR; GENETICS; HUMAN; LIVER; METABOLISM; MOUSE MUTANT; TIME;

ADENOVIRIDAE; ANIMALIA; CUCUMBER MOSAIC VIRUS; HUMAN HERPESVIRUS 5; MAIZE CHLOROTIC MOTTLE VIRUS; MURINAE;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CELL DIVISION; CYTOMEGALOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; HUMANS; IMMUNITY; INTERFERON TYPE II; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; PROMOTER REGIONS (GENETICS); T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; TRANSGENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034991473     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0318     Document Type: Article

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