Gene silencing and DNA methylation processes

Current Opinion in Plant Biology

Volumn 4, Issue 2, 2001, Pages 123-129

  Paszkowski, Jerzy ^a   Whitham, Steven A ^b  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLATION; GENE SILENCING; GENETIC REGULATION; RNA DEGRADATION;

CAENORHABDITIS ELEGANS; DROSOPHILA; MAMMALIA;

EID: 0035115727     PISSN: 13695266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5266(00)00147-3     Document Type: Review

References (47)

1. (Trans)gene silencing in plants: How many mechanisms?
2. Post-transcriptional gene-silencing: RNAs on the attack or on the defense?
3. Epigenetic developmental mechanisms in plants: Molecules and targets of plant epigenetic regulation
4. Plant DNA methyltransferases
5. DNA methylation in health and disease
6. Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida
7. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
8. A DNA methyltransferase homolog with a chromodomain exists in multiple polymorphic forms in Arabidopsis
9. Gene silencing: Maintaining methylation patterns
10. An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis
11. Position-dependent methylation and transcriptional silencing of transgenes in inverted T-DNA repeats: Implications for posttranscriptional silencing of homologous host genes in plants
12. Distinct features of post-transcriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci
13. Cytosine methylation at CG and CNG sites is not a prerequisite for the initiation of transcriptional gene silencing in plants, but it is required for its maintenance
14. Identification of a general silencer for 19S and 35S promoters in a transgenic tobacco plant: 90 bp of homology in the promoter sequence are sufficient for trans-inactivation
15. Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity
16. Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development
17. Meiotically and mitotically stable inheritance of DNA hypomethylation induced by ddm1 mutation of Arabidopsis thaliana
18. Maintenance of genomic methylation requires a SWl2/SNF2-like protein
19. Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
20. FASCIATA genes for chromatin assembly factor-1 in Arabidopsis maintain the cellular organization of apical meristems
21. Endogenous targets of transcriptional gene silencing in Arabidopsis
22. DNA methylation and chromatin structure affect transcriptional and post-transcriptional transgene silencing in Arabidopsis
23. Release of epigenetic gene silencing by trans-acting mutations in Arabidopsis
24. DNA methylation directs a time-dependent repression of transcription initiation
25. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
26. Mi-2 complex couples DNA methylation to chromatin remodeling and histone deacetylation
27. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
28. Blocking of histone deacetylation in Arabidopsis induces pleiotropic effects on plant gene regulation and development
29. Disruption of the plant gene MOM releases transcriptional silencing of methylated genes
30. Transcriptional silencing and promoter methylation triggered by double-stranded RNA
31. Arabidopsis PAI gene arrangements, cytosine methylation and expression
32. A DNA target of 30 bp is sufficient for RNA-directed DNA methylation
33. Heavy de novo methylation at symmetrical and non-symmetrical sites is a hallmark of RNA-directed DNA methylation
34. A species of small antisense RNA in posttranscriptional gene silencing in plants
35. The silence of genes
36. De novo methylation and co-suppression induced by a cytoplasmically replicating plant RNA virus
37. RNA-DNA interactions and DNA methylation in post-transcriptional gene silencing
38. The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila
39. Dosage compensation roxl
40. RNA and the epigenetic regulation of X chromosome inactivation
41. Fibrillarin genes encode both a conserved nucleolar protein and a novel small nucleolar RNA involved in ribosomal RNA methylation in Arabidopsis thaliana
42. Arabidopsis mutants impaired in cosuppression
43. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
44. AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
45. High-efficiency silencing of a beta-glucuronidase gene in rice is correlated with repetitive transgene structure but is independent of DNA methylation
46. Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing
47. Plant viral suppressors of posttranscriptional silencing do not suppress transcriptional silencing