Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 21, Issue 1, 2001, Pages 115-121

  Sparrow, Carl P ^a   Burton, Charlotte A ^a   Hernandez, Melba ^a   Mundt, Steven ^a   Hassing, Heide ^a   Patel, Sushma ^a   Rosa, Ray ^a   Hermanowski Vosatka, Anne ^a   Wang, Pei Ran ^a   Zhang, Donghui ^a   Peterson, Larry ^a   Detmers, Patricia A ^a   Chao, Yu Sheng ^a   Wright, Samuel D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

ApoE; Atherosclerosis; HMG CoA reductase; Inflammation; Mice

Indexed keywords

APOLIPOPROTEIN E; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME INHIBITION; GENE REARRANGEMENT; LEUKOCYTE ADHERENCE; LIPID BLOOD LEVEL; MOUSE; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEROL SYNTHESIS;

EID: 0035162266     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.21.1.115     Document Type: Article

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