Gene amplification in fibroblasts from ataxia telangiectasia (AT) patients and in X-ray hypersensitive AT-like Chinese hamster mutants

Carcinogenesis

Volumn 22, Issue 1, 2001, Pages 141-145

  Mondello, Chiara ^a   Faravelli, Maura ^b   Pipitone, Loredana ^c   Rollier, Anna ^b,d   Di Leonardo, Aldo ^c   Giulotto, Elena ^b  

^a CNR   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DOUBLE STRANDED DNA; SPARFOSIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA TELANGIECTASIA; CELL CYCLE G1 PHASE; CELL CYCLE PARAMETERS; CELL IMMORTALIZATION; CELL LINE; CELL STIMULATION; CHINESE HAMSTER; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA STRAND BREAKAGE; FIBROBLAST; GENE AMPLIFICATION; GENE CONTROL; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; X RAY;

EID: 0035132526     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/22.1.141     Document Type: Article

References (40)

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5. n sequences in gene amplification and chromosome stability
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15. DNA amplification is rare in normal human cells
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23. The defect in the AT-like hamster cell mutants is complemented by mouse chromosome 9 but not by any of the human chromosomes
24. Human chromosome 11 complements ataxia-telangiectasia cells but does not complement the defect in AT-like Chinese hamster cell mutants
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40. The distribution of the numbers of mutants in bacterial populations