Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome

EMBO Journal

Volumn 17, Issue 1, 1998, Pages 325-333

  Pipiras, E ^a   Coquelle, A ^a   Bieth, A ^a   Debatisse, M ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Deletions; Double strand breaks; Gene amplification; I SceI nuclease; Tumour progression

Indexed keywords

DIHYDROFOLATE REDUCTASE; DOUBLE STRANDED DNA; SINGLE STRANDED DNA;

ANIMAL CELL; ARTICLE; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA SEQUENCE; DNA STRAND BREAKAGE; GENE AMPLIFICATION; GENE DELETION; GENE INSERTION; GENE ISOLATION; GENE LOCUS; GENE MUTATION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TELOMERE; TUMOR SUPPRESSOR GENE;

CHROMOSOMES; CLONING, MOLECULAR; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA DAMAGE; GENE AMPLIFICATION; GENE DELETION; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0032472367     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.1.325     Document Type: Article

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