The contribution of exogenous and endogenous mutagens to in vivo mutations

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 428, Issue 1-2, 1999, Pages 11-15

  Morley, A A ^a   Turner, D R ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Diet; Mitotic recombination; Mutation spectrum; Mutations; Oxidizing free radical

Indexed keywords

ENVIRONMENTAL MUTAGEN; FREE RADICAL;

CANCER; CONFERENCE PAPER; DIET; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; HEREDITY; HUMAN; LYMPHOCYTE; MUTATION; MUTATION RATE; PRIORITY JOURNAL;

ANIMALS; DIET; FEMALE; HLA-A ANTIGENS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICE; MUTAGENS; MUTATION; NEOPLASMS;

EID: 0032808904     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5742(99)00026-5     Document Type: Conference Paper

References (6)

1. Brash D.E. Sunlight and the onset of skin cancer. TIG. 13:1997;410-414.
2. Morley A.A. The estimation of in vivo mutation rate and frequency from samples of human lymphocytes. Mutat. Res. 357:1996;167-176.
3. Dempsey J.L., Morley A.A., Pfeiffer M. Effect of dietary restriction on in vivo somatic mutation. Mutat. Res. 291:1993;141-145.
4. Odagiri Y., Uchida H., Hosokawa M., Takemoto K., Morley A.A., Takeda T. Accelerated accumulation of somatic mutations with age in lymphocytes of the senescence-accelerated mouse (SAM). Nat. Genet. 19:1998;117-118.
5. Morley A.A., Grist S.J., Turner D.R., Kutlaca A., Bennett G. The molecular nature of in vivo mutations in human cells at the autosomal HLA-A locus. Cancer Res. 50:1990;4584-4587.
6. Grist S.A., McCarron M., Kutlaca A., Turner D.R., Morley A.A. In vivo human somatic mutation: frequency and spectrum with age. Mutat. Res. 266:1991;189-196.