Expression of cell-cycle-associated proteins pRB2/p130 and p27kip1 in vulvar squamous cell carcinomas

Human Pathology

Volumn 32, Issue 1, 2001, Pages 4-9

  Zamparelli, Alessandra ^a,b   Masciullo, Valeria ^a,b   Bovicelli, Alessandro ^a,b   Santini, Donatella ^a,b   Ferrandina, Gabriella ^a,b   Minimo, Corrado ^a,b   Terzano, Patrizia ^a,b   Costa, Silvano ^a,b   Cinti, Caterina ^a,b   Ceccarelli, Claudio ^a,b   Mancuso, Salvatore ^a,b   Scambia, Giovanni ^a,b   Bovicelli, Luciano ^a,b   Giordano, Antonio ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

p27kip1; pRB2 p130; Prognostic factor; Squamous vulvar carcinoma

Indexed keywords

PROTEIN P130; PROTEIN P27;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CARCINOMA IN SITU; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE; VULVA CARCINOMA;

EID: 0035122583     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1053/hupa.2001.20371     Document Type: Article

References (31)

1. Retinoblastoma protein family in cell cycle and cance: A review
2. Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain
3. p130/RB2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107
4. Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retroviral-mediated gene transfer
5. The retinoblastoma gene family pRB/p105, p107, pRB2/p130 and Simian virus-40 large T-antigen in human mesotheliomas
6. Retinoblastoma related p107 and pRB2/p130 proteins in malignant lymphomas: Distinct mechanisms of cell growth control
7. Expression of the retinoblastoma-related gene Rb2/p 130 correlates with clinical outcome in endometrial cancer
8. Differential expression of the retinoblastoma gene family members in choroidal melanoma: Prognostic significance
9. Cyclins, cyclin-dependent kinases and cdk inhibitors: Implications in cell-cycle control and cancer
10. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p 27 in aggressive colorectal carcinomas
11. Down-regulation of p 27 is associated with development of colorectal adenocarcinoma metastases
12. Decreased levels of the cell-cycle inhibitor p27 kip 1 protein: Prognostic implications in primary, breast cancer
13. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
14. Loss of cyclin-dependent kinase inhibitor p 27 kip1 is a novel prognostic factor in localized human prostate adenocarcinoma
15. kip1 gene expression in benign prostatic hyperplasia and prostatic carcinoma
16. Loss or altered subcellular localization of the cyclin-dependent kinase inhibitor p27 in epithelial ovarian cancer
17. Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cyclin D1, RB, and EGFR in cervical carcinomas
18. Basaloid and warty carcinomas of the vulva: Distinctive types of squamous cell carcinoma frequently associated with human papillomaviruses
19. Expression of p 16INK4 and retinoblastoma protein Rb in vulvar lesions of Chinese women
20. Squamous cell carcinoma of the vulva: Study of ploidy, HPV, p53, and pRB
21. Differential expression of Rb2/p130 and p107 in normal human tissues and in primary lung cancer
22. Retinoblastoma-related protein pRB2/p130 and suppression of tumor growth in vivo
23. Ectopic expression of pRB2/p130 suppresses the tumorigenicity of the c-erbB- 2 overexpressing SKOV3 tumor cell line
24. Retinoblastoma-related gene Rb2/p130 expression in normal, hyperplastic and malignant endometrium
25. Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130
26. Genetic origin of mutations predisposing to retinoblastoma
27. The p53 proto-oncogene can act as a suppressor of transformation
28. Genetic alterations disrupting the nuclear localization of the retinoblastoma related gene RB2/p 130 in human cell lines and primary tumors
29. Loss of the cyclin-dependent kinase inhibitor p27 (Kip1) protein in human prostate cancer correlates with tumor grade
30. KP1 in multistage colorectal carcinogenesis