Nuclear dynamics: Where genes are and how they got there

Genome Biology

Volumn 2, Issue 3, 2001, Pages

  Swedlow, J R ^a   Lamond, A I ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CHROMATIN; CHROMOSOME; DNA REPLICATION; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; GENE REPLICATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PROTEIN DOMAIN; REVIEW;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CELL NUCLEUS STRUCTURES; CHROMATIN; GENE EXPRESSION REGULATION; GENES; HUMANS; MODELS, BIOLOGICAL;

EID: 0035087415     PISSN: 14656906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (56)

1. Visualization of gene activity in living cells
2. Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain
3. Signaling to chromatin through histone modifications
4. The Swi/Snf family nucleosome-remodeling complexes and transcriptional control
5. Polycombing the genome: PcG, trxG, and chromatin silencing
6. Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries
7. Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories
8. Nuclear compartments and gene regulation
9. Structure and dynamics of human interphase chromosome territories in vivo
10. Structure and function in the nucleus
11. Nuclear bodies: Multifaceted subdomains of the interchromatin space
12. Chromatin unfolds
13. Differences in the localization and morphology of chromosomes in the human nucleus
14. The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells
15. Spatial organization of large-scale chromatin domains in the nucleus: A magnified view of single chromosome territories
16. Nuclear organization of mammalian genomes. Polar chromosome territories build up functionally distinct higher order compartments
17. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
18. Variegation in Drosophila and the inert chromosome regions
19. A structural basis for variegating position effects
20. A reconsideration of the mechanism of position effect
21. Dominant heterochromatic element in Drosophila
22. Genetic modification of heterochromatic association and nuclear organization in Drosophila
23. Perturbation of nuclear architecture by long-distance chromosome interactions
24. A reexamination of spreading of position-effect variegation in the white-roughest region of Drosophila melanogaster
25. Chromatin opening of DNA satellites by targeted sequence-specific drugs
26. Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster
27. Yeast heterochromatin: Regulation of its assembly and inheritance by histones
28. Transcriptional regulation of early B-lymphocyte differentiation
29. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
30. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
31. Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
32. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin
33. An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells
34. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
35. In vivo visualization of chromosomes using lac operator-repressor binding
36. Interphase chromosomes undergo constrained diffusional motion in living cells
37. Cell nucleus: Chromosome dynamics in nuclei of living cells
38. Quantitative motion analysis of subchromosomal foci in living cells using four-dimensional microscopy
39. Nopp 140 shuttles on tracks between nucleolus and cytoplasm
40. High mobility of proteins in the mammalian cell nucleus
41. Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells
42. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator
43. Transport between the cell nucleus and the cytoplasm
44. Large-scale chromosomal movements during interphase progression in Drosophila
45. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: Precise choreography of condensation/decondensation and nuclear positioning
46. The positioning and dynamics of origins of replication in the budding yeast nucleus
47. The dynamics of a pre-mRNA splicing factor in living cells
48. Quantitative imaging of pre-mRNA splicing factors in living cells
49. In vivo analysis of Cajal body movement, separation and joining in live human cells
50. Mutational analysis of fibrillarin and its mobility in living human cells
51. The movement of coiled bodies visualized in living plant cells by the green fluorescent protein
52. Interactions of U2 gene loci and their nuclear transcripts with Cajal (coiled) bodies: Evidence for PreU2 within cajal bodies
53. U2 and U1 snRNA gene loci associate with coiled bodies
54. Coiled bodies preferentially associate with U4, U11, and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes
55. Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts
56. Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells