The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy suppressor of mec1 telomeric silencing defects

Genetics

Volumn 158, Issue 1, 2001, Pages 145-154

  Craven, Rolf J ^a   Petes, Thomas D ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CHOLINE; INOSITOL; PROTEIN KINASE;

ARTICLE; CELL AGING; GENE DELETION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SUPPRESSOR GENE; TELOMERE;

BASE SEQUENCE; DNA PRIMERS; FUNGAL PROTEINS; GENE SILENCING; GENES, FUNGAL; GENES, SUPPRESSOR; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERE;

EID: 0035024077     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
2. Modifiers of position effect are shared between telomeric and silent mating-type loci of S. cerevisiae
3. Components of the Ku-dependent non-homologous end joining pathway are involved in telomeric length maintanance and telomeric silencing
4. Multifunctional yeast high-copy-number shuttle vectors
5. Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae
6. Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae
7. Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe
8. Biosynthesis of inositol in yeast. Primary structure of myo-inositol-1-phosphate synthase (EC 5.5.1.4) and functional analysis of its structural gene, the INO1 locus
9. A septin-based hierarchy of proteins required for localized deposition of chitin in the Saccharomyces cerevisiae cell wall
10. Recovery from DNA replication stress is the essential function of the S-phase checkpoint pathway
11. Mutations in the RNA polymerase II transcription machinery suppress the hyperrecombination mutant hpr1 delta of Saccharomyces cerevisiae
12. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
13. Distortion of the DNA double helix by RAP1 at silencers and multiple telomere binding sites
14. The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae
15. Position effect at S. cerevisiae telomeres: Reversible effect of Pol II transcription
16. TEL1, a gene involved in controlling telomere length in S. cerevisciae, is homologous to the human Ataxia telengiectasia gene
17. Telomere length regulation
18. The role of phosphatidylcholine biosynthesis in the regulation of the INO1 gene of yeast
19. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation
20. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
21. Spreading of transcriptional repressor SIR3 from telomeric heterochromatin
22. Expression of the Saccharomyces cerevisiae Inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis
23. The Saccharomyces cerevisiae SCS2 gene product, a homolog of a Synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for Inositol metabolism
24. RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae
25. VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction
26. Checkpoint mutants influence telomeric silencing and length maintenance in budding yeast
27. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
28. Sensing and responding to DNA damage
29. Mechanisms of silencing in Saccharomyces cerevisiae
30. Identification of yeast mutants with altered telomere structure
31. Protein kinase activity of Tel1p and Mec1p, two S. cerevisiae proteins related to the human ATM protein kinase
32. +
33. Budding yeast centromere composition and assembly as revealed by in vino cross-linking
34. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
35. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1
36. Circular chromosome formation in a fission yeast mutant deficient in two ATM homologues
37. SET1, a member of the Trithorax family, functions in transcriptional silencing and diverse cellular processes
38. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
39. The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae
40. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
41. Interactions of TLC1 (which encodes the RNA sub-unit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
42. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
43. A VAMP-binding protein from Aplysia required for neurotransmittor release
44. Activation of an MAP kinase cascade leads to Sir3p hyperphosphorylation and strengthens transcriptional silencing
45. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
46. Elevated recombination rates in transcriptionally active DNA
47. Characterization of the yeast transcriptome
48. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
49. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
50. Saccharomyces telomeres assume a non-nucleosomal chromatin structure
51. A suppressor of two essential checkpoint genes identifies a protein that negatively effects dNTP pools
52. DUN1 encodes a protein kinase that controls the DNA damage response in yeast