Mutations in the RNA Polymerase II transcription machinery suppress the hyperrecombination Mutant hpr1Δ of Saccharomyces cerevisiae

Genetics

Volumn 142, Issue 3, 1996, Pages 749-759

  Fan, Hua Ying ^a   Cheng, Kenneth K ^a   Klein, Hannah L ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DNA; INITIATION FACTOR 2; MESYLIC ACID METHYL ESTER; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RNA POLYMERASE II;

ARTICLE; CONTROLLED STUDY; DNA REPAIR; ENZYME SUBUNIT; FUNGUS MUTANT; GENE MUTATION; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE; SUPPRESSOR GENE;

ADENOSINE TRIPHOSPHATASES; DNA REPAIR; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MUTATION; RECOMBINATION, GENETIC; REPRESSOR PROTEINS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTOR TFIIB; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0029670585     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. AGUILERA, A., and H. L. KLEIN, 1988 Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics 119: 779-790.
2. AGUILERA, A., and H. L. KLEIN, 1990 HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxyl-terminal homology to the Saccharomyces cerevisiae TOP1 gene. Mol. Cell. Biol. 10: 1439-1451.
3. ARNDT, K. T., C. A. STYLES and G. R. FINK, 1989 A suppressor of a HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases. Cell 56: 527-537.
4. 35S label as an aid to rapid DNA sequence determination. Proc. Natl. Acad. Sci. USA 80: 3963-3965.
5. FAN, H.-Y., and H. L. KLEIN, 1994 Characterization of mutations that suppress the temperature-sensitive growth of the hpr1Δ mutant of Saccharomyces cerevisiae Genetics 137: 945-956.
6. FEAVER, W. J., J. Q. SVEJSTRUP, L. BARDWELL, A. J. BARDWELL, S. BURATOWSKI et al., 1993 Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell 75: 1379-1387.
7. FEINBERG, A. P., and B. VOGELSTEIN, 1984 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity (Addendum). Anal. Biochem. 137: 266-267.
8. GUZDER, S. N., H. QIU, C. H. SOMMERS, P. SUNG, L. PRAKASH et al., 1994a DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II. Nature 367: 91-94.
9. GUZDER, S. N , P SUNG, V. BAILLY, L. PRAKASH and S. PRAKASH, 1994b Rad25 is a DNA helicase required for DNA repair and RNA polymerase II transcription [see comments]. Nature 369: 578-581.
10. GYURIS, J., E. GOLEMIS, H. CHERTKOV and R. BRENT, 1993 Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2 Cell 75: 791-803.
11. HAMPSEY, M., 1991 A tester system for detecting each of the six base-pair substitutions in Saccharomyces cerevisiae by selecting for an essential cysteine in iso-I-cytochrome c. Genetics 128: 59-67.
12. HEKMATPANAH, D. S., and R. A. YOUNG, 1991 Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection. Mol. Cell. Biol. 11: 5781-5791
13. HILL, J., K. A. DONALD, D. E. GRIFFITHS and K. A. DONALD, 1991 DMSO-enhanced whole cell yeast transformation [published erratum appears in Nucleic Acids Res. 1991 Dec 11;19(23):6688]. Nucleic Acids Res 19: 5791.
14. HOFFMAN, C. S., and F. WINSTON, 1987 A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57: 267-272.
15. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact yeast cells treated with alkali cations. J. Bacteriol 153: 163-168.
16. JOHNSON, R. E., S. T. HENDERSON, T. D. PETES, S. PRAKASH, M. BANKMANN et al., 1992 Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome. Mol. Cell. Biol. 12: 3807-3818.
17. JOHNSON, R. E., S. PRAKASH and L. PRAKASH, 1994 Yeast DNA repair protein Rad5 that promotes instability of simple repetitive sequences is a DNA-dependent ATPase. J. Biol. Chem. 269: 28259-28262.
18. KLEIN, H. L., 1995 Genetic control of intrachromosomal recombination. Bioassays 17: 147-159.
19. LAURENT, B. C., M. A. TREITEL and M. CARLSON, 1991 Functional interdependence of the yeast Snf2, Snf5, and Snf6 proteins in transcriptional activation. Proc. Natl. Acad. Sci. USA 88: 2687-91.
20. LEA, D. E., and C. A. COULSON, 1948 The distribution of the numbers of mutants in bacterial populations. J. Genet. 49: 264-284.
21. MILLER, J. L., 1972 Experiments in Molecular Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
22. NONET, M. L., and R. A. YOUNG, 1989 Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123: 715-724.
23. NONET, M , D. SWEETSER and R. A. YOUNG, 1987 Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell 50: 909-915.
24. ORR-WEAVER, T. L., and J. W. SZOSTAK, 1983 Yeast recombination: the association between double-strand gap repair and crossing-over. Proc. Natl. Acad. Sci. USA 80: 4417-4421.
25. PINTO, I., D. E. WARE and M. HAMPSEY, 1992 The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo. Cell 68: 977-988.
26. ROSE, M. D., F. WINSTON and P. HIETER, 1990 In Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
27. SAMBROOK, J., E. F. FRITSCH and T. MANIATIS, 1989 In Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
28. SANGER, F., S. NICKLEN and A. R. COULSON, 1977 DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. SCc. USA 74: 5463-5467.
29. SCAFE, C., D. CHAO, J. LOPES, J. P. HIRSCH, S HENRY et al., 1990 RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals. Nature 347: 491-494.
30. SHERMAN, F., G. R. FINK and J. B. HICKS, 1986 Methods in Yeast Genetics. Cold Spring Harbor Press, Cold Spring Harbor, NY.
31. SUNG, P., D. HIGGINS, L. PRAKASH and S. PRAKASH, 1988 Mutation of lysine-48 to arginine in the yeast Rad3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP. EMBO J. 7: 3263-3269.
32. SVEJSTRUP, J. Q., W. J. FEAVER, J. LAPOINT and R. D. KORNBERG, 1994 RNA polymerase transcription factor IIH from yeast. J. Biol. Chem. 269: 28044-28048.
33. TABOR, S., and C. C. RICHARDSON, 1987 DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Proc. Natl. Acad. Sci. USA 84: 4767-4771.
34. THOMAS, B. J., and R. ROTHSTEIN, 1989 The genetic control of direct-repeat recombination in Saccharomyces: the effect of rad52 and rad1 on mitotic recombination at GAL10, a transcriptionally regulated gene. Genetics 123: 725-738.
35. THOMPSON, C. M., A. J. KOLESKE, D. M. CHAO and R. A. YOUNG, 1993 A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73: 1361-1375.
36. VOELKEL-MEIMAN, K., and G. S. ROEDER, 1990 A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversion. Genetics 124: 561-572.
37. ZHU, Y., C. L. PETERSON and M. F. CHRISTMAN, 1995 HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae Mol. Cell. Biol. 15: 1698-1708.