Anxiolytic and anticonvulsant activity of a synthetic neuroactive steroid Co 3-0593

Psychopharmacology

Volumn 134, Issue 1, 1997, Pages 46-54

  Wieland, Scott ^a   Belluzzi, James ^b   Hawkinson, Jon E ^a   Hogenkamp, Derk ^a   Upasani, Ravi ^a   Stein, Larry ^b   Wood, Paul L ^a   Gee, Kelvin W ^b   Lan, Nancy C ^a  

^a Department of Pharmacokinetics and Drug Metabolism   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anticonvulsant; Anxiolytic; GABA(A) receptor; Neuroactive steroid; Neurosteroid

Indexed keywords

3BETA ETHENYL 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; CO 3 0593; DIAZEPAM; FLUNITRAZEPAM; LORAZEPAM; MUSCIMOL; NEUROSTEROID; PENTETRAZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANXIETY; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; MAZE TEST; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; SEIZURE; SUBCUTANEOUS DRUG ADMINISTRATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; AVOIDANCE LEARNING; BINDING, COMPETITIVE; CEREBRAL CORTEX; FLUNITRAZEPAM; GABA AGONISTS; GABA MODULATORS; MALE; MICE; MUSCIMOL; MUSCULOSKELETAL EQUILIBRIUM; PHENOLSULFONPHTHALEIN; PREGNANOLONE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 0030656601     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050424     Document Type: Article

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