Immunohistochemical distribution and quantitative biochemical detection of advanced glycation end products in fetal to adult rats and in rats with streptozotocin-induced diabetes

Laboratory Investigation

Volumn 81, Issue 6, 2001, Pages 845-861

  Ling, Xia ^a   Nagai, Ryoji ^a   Sakashita, Naomi ^a   Takeya, Motohiro ^a   Horiuchi, Seikoh ^a   Takahashi, Kiyoshi ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY;

ADOLESCENT; AGING; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; DIABETES MELLITUS; ERYTHROCYTE; FETUS; GLYCATION; HYPERGLYCEMIA; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; LABORATORY DIAGNOSIS; LEYDIG CELL; LIVER CELL; MACROPHAGE; MESANGIUM CELL; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 0034979664     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780294     Document Type: Article

References (83)

1. ε-(Carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins
2. ε-(carboxymethyl)lysine as a degradation product of fructoselysine in glycated protein
3. ε-(carboxymethyl)lysine on protein: A mechanism for producing advanced glycation end products at sites of inflammation
4. Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging
5. Effect of acute ketosis on the endothelial function of type 1 diabetic patients: The role of nitric oxide
6. Increased serum levels of advanced glycation end products (AGEs) in children and adolescents with IDDM
7. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
8. Lipid advanced glycosylation: Pathway for lipid oxidation in vivo
9. Modification of DNA by reducing sugars: A possible mechanism for nucleic acid aging and age-related dysfunction in gene expression
10. Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease
11. Synthesis of a fluorescent derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, and its application for the analysis of hydrolysate amino acids via high-performance liquid chromatography
12. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
13. Chemical modification of proteins by methylglyoxal
14. Immunological determination of advanced glycosylation end-products in human blood and urine
15. Receptor for advanced glycation end products (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung
16. Presence of dopa and amino acid hydroperoxides in proteins modified with advanced glycation end products (AGEs): Amino acid oxidation products as a possible source of oxidative stress induced by AGE proteins
17. Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction
18. Cytochemical demonstration of peroxidase activity with 3-amino-9-ethylcarbazole
19. Rapid formation of advanced glycation end products by intermediate metabolites of glycolytic pathway and polyol pathway
20. The role of glycation in cataract lens in diabetic patients
21. Aging of proteins: Immunological detection of a glucose-derived pyrrole formed during Maillard reaction in vivo
22. Immunochemical approach to characterize advanced glycation end products of the Maillard reaction: Evidence for the presence of a common structure
23. A new fluorescent crosslinker (AGE-×1) isolated from AGE-lysine derivatives
24. Immunohistochemical study with anti-advanced glycation end-products antibody in murine amyloidosis
25. ε-(Carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction
26. Immunochemical approaches to AGE-structures: Characterization of anti-AGE antibodies
27. Studies on translocation of immunoglobulins across interstitial epithelium. I. Improvements in the peroxidase-labeled antibody method for application to study of human interstitial mucosa
28. Ketosis (acetoacetate) can generate oxygen radicals and cause increased lipid peroxidation and growth inhibition in human endothelial cells
29. Hyperketonemia can increase lipid peroxidation and lower glutathione levels in human erythrocytes in vitro and in type 1 diabetic patients
30. The liver cell histones of diabetic patients contain glycation endproducts (AGEs) which may be lipofuscin components
31. Use of animal models in the study of diabetes
32. Type II alveolar epithelial cells in lung express receptor for advanced glycation end products (RAGE) gene
33. Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic nephropathy
34. Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta with a novel specific monoclonal antibody
35. Effect of glycation of albumin on its renal clearance in normal and diabetic rats
36. Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus
37. Immunohistochemical distribution and subcellular localization of three distinct specific molecular structures of advanced glycation end products in human tissues
38. Action des acides amines sur les sucres: Formation des melanoidines par voie méthodique
39. Immunohistochemical localisation of advanced glycation end products in pulmonary fibrosis
40. Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications
41. Immunochemical detection of advanced glycation end products in renal cortex from STZ-induced diabetic rat
42. Standardizing the immunological measurement of advanced glycation endproducts using normal human serum
43. Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers
44. ε-(carboxymethyl)lysine, one of the glycoxidation products of the Maillard reaction
45. Localization of advanced glycation end products of Maillard reaction in bovine tissues and their endocytosis by macrophage scavenger receptors
46. Determination of advanced glycation end products in serum by fluorescence spectroscopy and competitive ELISA
47. ε(carboxymethyl)lysine formation from Amadori product
48. Glycolaldehyde, a reactive intermediate for advanced glycation endproducts, plays an important role in the generation of an active ligand for the macrophage scavenger receptor
49. Protein cross-linking by the Maillard reaction
50. Cross-lines A and B as candidates for the fluorophores in age- and diabetes-related cross-linked proteins, and their diacetates predicted by Maillard reaction of α-N-acetyl-L-lysine with D-glucose
51. Acid-stable fluorescent advanced glycation end products: Vesperlysines A, B, and C are formed as crosslinked products in the Maillard reaction between lysine or proteins with glucose
52. Immunochemical detection of advanced glycation end products in lens crystallins from streptozocin-induced diabetic rat
53. Myeloperoxidase deficiency
54. Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes
55. Formation of crossline as a fluorescent advanced glycation end product in vitro and in vivo
56. Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: Evidence for increased oxidative stress in uremia
57. Ultrastructural changes in Leydig cells of streptozotocin-induced diabetic rats
58. Leydig cell function in streptozotocin-induced diabetic rats
59. ε-(Carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins
60. Acetone metabolism in humans during diabetic keto-acidosis
61. Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance
62. The principal site of nonenzymatic glycosylation of human serum albumin in vivo
63. Localization of glycated proteins in the glomeruli of patients with diabetic nephropathy
64. Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases
65. Advanced glycation end-products (AGEs) induce oxidant stress in the gingiva: A potential mechanism underlying accelerated periodontal disease associated with diabetes
66. Effects of age and diabetes mellitus on the solubility and nonenzymatic glycosylation of human skin collagen
67. Advanced glycation end products in human penis: Elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS
68. Structure elucidation of a senescence cross-link from human extracellular matrix: Implication of pentoses in the aging process
69. Advanced glycation end products are eliminated by scavenger-receptor mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cells
70. Measurement of protein using bicinchoninic acid
71. Advanced glycation end products in vitreous: Structural and functional implications for diabetic vitreopathy
72. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
73. Pharmacology of methylglyoxal: Formation, modification of proteins and nucleic acids, and enzymatic detoxification: A role in pathogenesis and antiproliferative chemotherapy
74. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
75. Myeloperoxidase: Localization, structure and function
76. Protein modification by a Maillard reaction intermediate methylglyoxal: Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo
77. Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging
78. Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): A new member of the AGE-receptor complex
79. Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: A link between surface-associated AGEs and diabetic complications
80. New biomarkers of Maillard reaction damage to proteins
81. Pathways of formation of glycoxidation products during glycation of collagen
82. Investigation of the bicinchoninic acid protein assay: Identification of the groups responsible for color formation
83. Hepatic advanced glycation endproduct binding is increased in experimental diabetes