Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cDNA-expressed human cytochrome P450

Drug Metabolism and Disposition

Volumn 24, Issue 9, 1996, Pages 940-947

  Ghosal, Anima ^a   Satoh, Hiroko ^a   Thomas, Paul E ^b   Bush, Ernest ^a   Moore, David ^a  

^a HOFFMANN LA ROCHE INC   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; DRUG METABOLITE; KETOCONAZOLE; MIDAZOLAM; NARINGENIN; POLYCLONAL ANTIBODY;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; KINETICS; LIVER MICROSOME METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANESTHETICS, INTRAVENOUS; ANIMALS; ANTI-ANXIETY AGENTS; ANTIBODIES; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; HUMANS; KINETICS; MALE; MICROSOMES, LIVER; MIDAZOLAM; MIXED FUNCTION OXYGENASES; OXIDOREDUCTASES, N-DEMETHYLATING; PIPERIDINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

ANIMALIA; CITRUS X PARADISI; STAPHYLOCOCCUS PHAGE 3A;

EID: 0029790347     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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