Regulation of Id gene expression by type 1 insulin-like growth factor: Roles of STAT3 and the tyrosine 950 residue of the receptor

Molecular and Cellular Biology

Volumn 21, Issue 16, 2001, Pages 5447-5458

  Prisco, M ^a   Peruzzi, F ^a   Belletti, B ^a   Baserga, R ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR; STAT3 PROTEIN; TYROSINE;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; DNA-BINDING PROTEINS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; INSULIN-LIKE GROWTH FACTOR I; MICE; RECEPTOR, IGF TYPE 1; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TYROSINE;

EID: 0034934621     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.16.5447-5458.2001     Document Type: Article

References (69)

1. Immortalization of primary human keratinocytes by the helix-loop-helix protein
2. Id proteins control growth induction in mammalian cells
3. Differentiation and malignant transformation: Two roads diverged in a wood
4. IGFs and cell growth
5. Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor
6. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
7. IGF-I receptor function: Transducing the IGF-I signal into intracellular events
8. Monocytically differentiating HL60 cells proliferate rapidly before they mature
9. Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs
10. An Id-related helix-loop-helix protein encoded by a growth factor inducible gene
11. Differential expression of Id genes in multipotent myeloid progenitor cells: Id1 is induced by early- and late-acting cytokines while Id2 is selectively induced by cytokines that drive terminal granulocytic differentiation
12. Expression of the Id family helix-loop-helix regulators during growth and development in the hematopoietic system
13. Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor-I receptor
14. Co-operative transformation of 32D cells by the combined expression of IRS-1 and v-Ha-Ras
15. Kip1.
16. Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1
17. A novel pathway for mammary epithelial cell invasion by the helix-loop-helix protein Id-1
18. Domains of the IGF-I receptor required for the activation of extracellular signal-regulated kinases
19. Regulation of neuronal survival by the serine-threonine protein kinase Akt
20. Ribosomal S6 kinase signaling and the control of translation
21. SOCS-3 is an insulin-induced negative regulator of insulin signaling
22. New insights into the control of MAP kinase pathways
23. Id2 promotes apoptosis by a novel mechanism independent of dimerization to basic helix-loop-helix factors
24. Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells
25. Organization and regulation of mitogen-activated protein kinase signaling pathways
26. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
27. Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor 1 receptor
28. Id related genes encoding HLH proteins are required for G1 progression and are repressed in senescent human fibroblasts
29. Versatile retroviral vectors for potential use in gene therapy
30. The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein
31. Id2 expression increases with differentiation of human myeloid cells
32. Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis
33. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
34. Matrix adhesion and ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/AAkt cellular survival pathway
35. Interaction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor 1 receptor
36. Inhibition of myeloid differentiation by the helix-loop-helix protein Id
37. Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor 1
38. Id2 is a retinoblasoma protein target and mediates signaling by Myc oncoproteins
39. A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells
40. Inhibition of an erythroid differentiation switch by the helix-loop-helix protein Id1
41. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
42. STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line
43. A central role of Stat3 on IL-6-induced regulation of growth and differentiation in M1 leukemia cells
44. Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor
45. Id-1 delays senescence but does not immortalize keratinocytes
46. Id helix-loop-helix proteins in cell growth and differentiation
47. STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
48. Multiple signaling pathways of the IGF-I receptor in protection from apoptosis
49. Insulin and IGF-I receptor signaling in protection from apoptosis
50. Essential role of STAT3 for embryonic stem cell pluripotency
51. Insulin-like growth factor I inhibits apoptosis in IL-3 dependent hemopoietic cells
52. ras-GTP formation
53. Platelet derived growth factor and the regulation of the mammalian fibroblast cell cycle
54. Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells
55. Insulin-like growth factor 1 synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression
56. Suppression of G-CSF-mediated Stat signalling by IL-3
57. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins
58. Evidence for a differential interaction of SHC and the insulin receptor substrate-1 (IRS-1) with the insulin-like growth factor-I (IGF-I) receptor in the yeast two-hybrid system
59. Insulin receptor substrate-1, p70S6K and cell size in transformation and differentiation of hemopoietic cells
60. Growth and differentiation signals by the insulin-like growth factor I receptor in hemopoietic cells are mediated through different pathways
61. Cytokine dependent granulocytic differentiation
62. IRS-1: Essential for insulin- and IL-4-stimulated mitogenesis in hemopoietic cells
63. Multiple signals mediate proliferation, differentiation and survival from the granulocyte-colony stimulating factor receptor in myeloid 32D cells
64. The IRS-signalling system: A network of docking proteins that mediate insulin action
65. Activation of Stat3 signaling pathway is required for differentiation by interleukin-6 in OC12-E2 cells
66. The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin
67. Activation of Stat3 in v-src transformed fibroblasts requires cooperation of Jak1 kinase activity
68. Mechanism of STAT3 activation by insulin-like growth factor I receptor
69. Stat3 plays an important role in oncogenic ros- and insulin-like growth factor 1 receptor-induced anchorage-independent growth