Loss of fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development

Laboratory Investigation

Volumn 81, Issue 7, 2001, Pages 977-986

  Seeberger, H ^a   Starostik, P ^a   Schwarz, S ^a   Knorr C ^a   Kalla, J ^a   Ott, G ^a   Muller Hermelink H K ^a   Greiner, A ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; FAS ANTIGEN;

ARTICLE; AUTOIMMUNE DISEASE; CARCINOGENESIS; CELL DEATH; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOMA; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0034931133     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780310     Document Type: Article

References (56)

1. Ligation of CD40 rescues Ramos-Bukitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP
2. Growing human B lymphocytes in the CD40 system
3. Missense mutations in the Fas gene resulting in autoimmune lympho-proliferative syndrome: A molecular and immunological analysis
4. Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing
5. Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis
6. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule
7. IAP family proteins: Suppressors of apoptosis
8. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
9. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa- associated lymphoid tissue lymphomas
10. Serum soluble Fas antigen in gastric MALT (mucosa-associated lymphoid tissue) lymphoma patients
11. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
12. Detection of polymorphisms within the Fas cDNA gene sequence by GC-clamp denaturing gradient gel electrophoresis
13. Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
14. CD40 ligand and autoantigen are involved in the pathogenesis of low-grade B-cell lymphomas of mucosa-associated lymphoid tissue
15. Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation
16. Recent advances in gastric extranodal B-cell lymphoma
17. Somatic Fas mutations in non-Hodgkin's lymphoma: Association with extranodal disease and autoimmunity
18. Immunoglobulin VH genes of high-grade mucosa-associated lymphoid tissue lymphomas show a high load of somatic mutations and evidence of antigen-dependent affinity maturation
19. A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
20. Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue
21. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
22. Identification of soluble APO-1 in supernatants of human B- and T-cell lines and increased serum levels in B- and T-cell leukemias
23. Expression of costimulatory molecules in low-grade mucosa-associated lymphoid tissue-type lymphomas in vivo
24. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
25. Alterations of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder
26. Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer
27. Resistance to apoptosis correlates with a highly proliferative phenotype and loss of Fas and CPP32 (caspase-3) expression in human leukemia cells
28. Elevated soluble Fas (sFas) levels in nonhematopoietic human malignancy
29. Somatic mutations of the CD95 gene in Hodgkin and Reed-Sternberg cells
30. Apoptosis by death factor
31. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT-) type
32. Fas/APO-1 expression and function on malignant cells of hematologic and nonhematologic origin
33. Nonimmunoglobulin gene hypermutation in germinal center B cells
34. The use of 7-amino actinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
35. Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis
36. Intraclonal offspring expansion of gastric low-grade MALT-type lymphoma: Evidence for the role of antigen-driven high-affinity mutation in lymphomagenesis
37. Gastro-intestinal malignant lymphomas of the mucosa-associated lymphoid tissue: Factors relevant to prognosis
38. Expansion or elimination of B cells in vivo: Dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor
39. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
40. Exclusive detection of the t(11;18)(q21;q21) in extranodal marginal zone B cell lymphomas (MZBL) of MALT type in contrast to other MZBL and extranodal large B cell lymphomas
41. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
42. DNA sequencing with chain-terminating inhibitors
43. Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
44. Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma
45. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
46. Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis
47. Genetic aberrations common in gastric high-grade large B-cell lymphoma
48. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
49. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
50. Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase
51. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
52. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
53. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types
54. In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes
55. Soluble Fas in the serum of patients with non-Hodgkin's lymphoma: Higher concentrations in angioimmunoblastic T-cell lymphoma