Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT- type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation

American Journal of Pathology

Volumn 150, Issue 5, 1997, Pages 1583-1593

  Greiner, Axel ^a,d   Knörr, Constanze ^a   Qin, Yufen ^a   Sebald, Walter ^a   Schimpl, Anneliese ^b   Banchereau, Jacques ^c   Müller Hermelink, Hans Konrad ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MERCK RESEARCH LABORATORIES   (United States)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN;

ARTICLE; B CELL LYMPHOMA; CANCER GRADING; CANCER GROWTH; CELL DIFFERENTIATION; HELPER CELL; HUMAN; HUMAN TISSUE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 1842370945     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Isaacson PG: Pathogenesis and early lesions in extranodal lymphoma. Toxicol Lett 1993, 67:237-247
2. Isaacson PG: Gastrointestinal lymphoma. Hum Pathol 1994, 25:1020-1029
3. Isaacson PG, Wotherspoon AC, Diss T, Pan LX: Follicular colonization in B-cell lymphoma of mucosa-associated lymphoid tissue. Am J Surg Pathol 1991, 15: 819-828
4. Hussell T, Isaacson PG, Crabtree JE, Dogan A, Spencer J: Immunoglobulin specificity of low grade B cell gastrointestinal lymphoma of mucosa-associated lymphoid tissue (MALT) type. Am J Pathol 1993, 142: 285-292
5. Greiner A, Marx A, Heesemann J, Leebmann J, Schmausser B, Müller-Hermelink HK: Idiotype identity in a MALT-type lymphoma and B cells in Helicobacter pylori-associated chronic gastritis. Lab Invest 1994, 70: 572-578
6. Hussell T, Isaacson PG, Spencer J: Proliferation and differentiation of tumour cells from B-cell lymphoma of mucosa-associated lymphoid tissue in vitro. J Pathol 1993, 169:221-227
7. Greiner A, Marx A, Schmausser B, Müller-Hermelink HK: The pivotal role of the immunoglobulin receptor of tumor cells from B cell lymphomas of mucosa associated lymphoid tissue (MALT). Adv Exp Med Biol 1994, 355:189-193
8. Qin Y, Greiner A, Trunk MJ, Schmausser B, Ott MM, Müller-Hermelink HK: Somatic hypermutation in low-grade mucosa-associated lymphoid tissue-type B-cell lymphoma. Blood 1995, 86:3528-534
9. Hussell T, Isaacson PG, Crabtree JE, Spencer J: The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 1993, 342:571-574
10. Funakoshi S, Longo DL, Beckwith M, Conley DK, Tsarfaty G, Tsarfaty I, Armitage RJ, Fanslow WC, Spriggs MK, Murphy WJ: Inhibition of human B-cell lymphoma growth by CD40 stimulation. Blood 1994, 83:2787-2794
11. Carbone A, Gloghini A, Gattei V, Aldinucci D, Degan M, De Paoli P, Zagonel V, Pinto A: Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. Blood 1995, 85:780-789
12. Johnson PW, Watt SM, Betts DR, Davies D, Jordan S, Norton AJ, Lister TA: Isolated follicular lymphoma cells are resistant to apoptosis and can be grown in vitro in the CD40/stromal cell system. Blood 1993, 82:1848-1857
13. Dunn Walters DK, Isaacson PG, Spencer J: Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J Exp Med 1995, 182: 559-566
14. Graf D, Korthauer U, Mages HW, Senger G, Kroczek RA: Cloning of TRAP, a ligand for CD40 on human T cells. Eur J Immunol 1992, 22:3191-3194
15. Banchereau J, Bazan F, Blanchard D, Briers F, Galizzi JP, van Kooten C, Liu YJ, Rousset F, Saeland S: The CD40 antigen and its ligand. Annu Rev Immunol 1994, 12:881-922
16. Armitage RJ, Macduff BM, Spriggs MK, Fanslow WC: Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. J Immunol 1993, 150:3671-3680
17. Durie FH, Foy TM, Masters SR, Laman JD, Noelle RJ: The role of CD40 in the regulation of humoral and cell-mediated immunity. Immunol Today 1994, 15: 406-411
18. MacLennan IC: Germinal centers. Annu Rev Immunol 1994, 12:117-139
19. Man S, Hathcock K, Zheng B, Kepler TB, Modes R, Kelsoe G: Cellular interaction in germinal centers: roles of CD40 ligand and B7-2 in established germinal centers. J Immunol 1995, 155:556-567
20. Arpin C, Dechanet J, van Kooten C, Merville P, Grouard G, Briere F, Banchereau J, Liu YJ: Generation of memory B cells and plasma cells In vitro. Science 1995, 268:720-722
21. Burdin N, van Kooten C, Galibert L, Abrams JS, Wijdenes J, Banchereau J, Rousset F: Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 1995, 154: 2533-2544
22. +) B cells to secrete lgG1 and lgG3. J Exp Med 1994, 179:757-762
23. Fluckiger AC, Garrone P, Durand I, Galizzi JP, Banchereau J: Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. J Exp Med 1993, 178:1473-1481
24. Hsu SM, Waldron JW Jr, Hsu PL, Hough AJ Jr: Cytokines in malignant lymphomas: review and prospective evaluation. Hum Pathol 1993, 24:1040-1057
25. Bayerdorffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S, Stolte M: Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection: MALT Lymphoma Study Group. Lancet 1995, 345:1591-1594
26. Wotherspoon AC, Doglioni C, Diss TC, Pan L, Moschini A, de Boni M, Isaacson PG: Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 1993, 342:575-577
27. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, Delsol G, De Wolf Peeters C, Falini B, Gatter KG, et al: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group, Blood 1994, 84:1361-1392
28. Greiner A, Müller-Hermelink HK: Recent advances in gastric extranodal B-cell lymphoma. Curr Diagn Pathol 1996, 3:91-98
29. Radaszkiewicz T, Dragosics B, Bauer P: Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Gastroenterology 1992, 102:1628-1638
30. Schmid I, Krall WJ, Uittenbogaart CH, Braun J, Giorgi JV: Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry 1992, 13: 204-208
31. Banchereau J, Rousset F: Growing human B lymphocytes in the CD40 system. Nature 1991, 353:678-679
32. Küppers R, Zhao M, Hansmann ML, Rajewsky K. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J 1993, 12:4955-4967
33. Malisan F, Fluckiger AC, Ho S, Guret C, Banchereau J, Martinez Valdez H: B-chronic lymphocytic leukemias can undergo isotype switching in vivo and can be induced to differentiate and switch in vitro. Blood 1996, 87:717-724
34. Grouard G, de Bouteiller O, Banchereau J, Liu YJ: Human follicular dendritic cells enhance cytokine-dependent growth and differentiation of CD40-activated B cells. J Immunol 1995, 155:3345-3352
35. Liu YJ, Malisan F, de Bouteiller O, Guret C, Lebecque S, Banchereau J, Mills FC, Max EE, Martinez Valdez H: Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity 1996, 4:241-250
36. Bateman AC, Wright DH: Epitheliotropism in high-grade lymphomas of mucosa-associated lymphoid tissue. Histopathology 1993, 23:409-415
37. Rousset F, Garcia E, Defrance T, Peronne C, Vezzio N, Hsu DH, Kastelein R, Moore KW, Banchereau J. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992, 89:1890-1893
38. Racke MK, Bonomo A, Scott DE, Cannella B, Levine A, Raine CS, Shevach EM, Rocken M: Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 1994, 180:1961-1966
39. Fox RI, Kang HI, Ando D, Abrams J, Pisa E: Cytokine mRNA expression in salivary gland biopsies of Sjogren's syndrome. J Immunol 1994, 152:5532-5539
40. Kindler V, Matthes T, Jeannin P, Zubler RH: Interleukin-2 secretion by human B lymphocytes occurs as a late event and requires additional stimulation after CD40 cross-linking. Eur J Immunol 1995, 25:1239-1243
41. Vajdy M, Kosco Vilbois MH, Kopf M, Kohler G, Lycke N: Impaired mucosal immune responses in interleukin 4-targeted mice. J Exp Med 1995, 181:41-53
42. Hiroi T, Fujihashi K, McGhee JR, Kiyono H: Polarized Th2 cytokine expression by both mucosal γδ and αβ T cells. Eur J Immunol 1995, 25:2743-2751
43. Morikawa Y, Tohya K, Ishida H, Matsuura N, Kakudo K: Different migration patterns of antigen-presenting cells correlate with Th1/Th2-type responses in mice. Immunology 1995, 85:575-581
44. Romagnani S: Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994, 12: 227-257
45. Hodgkin PD, Basten A: B cell activation, tolerance and antigen-presenting function. Curr Opin Immunol 1995, 7:121-129
46. Wotherspoon AC, Finn TM, Isaacson PG: Trisomy 3 in low-grade B-cell lymphomas of mucosa-associated lymphoid tissue. Blood 1995, 85:2000-2004
47. Roblick U, Ott G, Kalla J, Hahn U, Ott MM, Müller-Hermelink HK: Nachweis numerischer Chromosome-nabberationen in primären gastralen Non-Hodgkin-Lymphomen durch in-situ-Hybridisierung mit centromerspezifischen DNA-Proben am Gefrierschnitt. Verh Dtsch Ges Pathol 1993, 77:487
48. Marin MC, Hsu B, Stephens LC, Brisbay S, McDonnell TJ: The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis In vivo. Exp Cell Res 1995, 217:240-247
49. Ott G, Kirchner T, Seidl S, Müller-Hermelink HK: Primary gastric lymphoma is rarely associated with Epstein-Barr virus, Virchows Arch B Cell Pathol Incl Mol Pathol 1993, 64:287-291
50. Greiner A, Kirchner T, Ott G, Marx A, Fischbach W, Müller-Hermelink HK: Occurrence of multiple lymphoepithelioma-like carcinomas and MALT-type lymphoma in the stomach: detection of EBV in carcinomas but not in lymphoma. Histopathology 1996, 29:51-56
51. Miyazaki T, Liu ZJ, Kawahara A, Minami Y, Yamada K, Tsujimoto Y, Barsoumian EL, Permutter RM, Taniguchi T: Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and Ick cooperate in hematopoietic cell proliferation. Cell 1995, 81:223-231
52. Cheng G, Cleary AM, Ye ZS, Hong DI, Lederman S, Baltimore D: Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science 1995, 267:1494-1498
53. Morio T, Hanissian S, Geha RS: Characterization of a 23-kDa protein associated with CD40. Proc Natl Acad Sci USA 1995, 92:11633-11636