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Volumn 20, Issue 12, 1999, Pages 2361-2365

O6-methylguanine-DNA methyltransferase activity, p53 gene status and BCNU resistance in mouse astrocytes

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NITROSOUREA; PROTEIN P53;

EID: 0033377369     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.12.2361     Document Type: Article
Times cited : (16)

References (63)
  • 2
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S.J., Plunkett, B.S., Walsh, W.V. and Kastan, M.B. (1992) Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl Acad. Sci. USA, 89, 7491-7495.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.J.1    Plunkett, B.S.2    Walsh, W.V.3    Kastan, M.B.4
  • 3
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone, L.R., White, A., Sprouse, J., Livanos, E., Jacks, T. and Tlsty, T.D. (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell. 70, 923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 4
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin, Y., Tainsky, M.A., Bischoff, F.Z., Strong, L.C. and Wahl, G.M. (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell, 70, 937-948.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 6
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S.W., Ruley, H.E., Jacks, T. and Housman, D.E. (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74, 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 7
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A. and Jacks, T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes [see comments]. Nature, 362, 847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 9
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDRI gene by Ras and p53
    • Chin, K.V., Ueda, K., Pastan, I. and Gottesman, M.M. (1992) Modulation of activity of the promoter of the human MDRI gene by Ras and p53. Science, 255, 459-462.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 10
    • 0027191153 scopus 로고
    • The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53
    • Zastawny, R.L., Salvino, R., Chen, J., Benchimol, S. and Ling, V. (1993) The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. Oncogene, 8, 1529-1535.
    • (1993) Oncogene , vol.8 , pp. 1529-1535
    • Zastawny, R.L.1    Salvino, R.2    Chen, J.3    Benchimol, S.4    Ling, V.5
  • 11
    • 0028109125 scopus 로고
    • Transactivation of the human multidrug resistance (MDRI) gene promoter by p53 mutants
    • Nguyen, K.T., Liu, B., Ueda, K., Gottesman, M.M., Pastan, I. and Chin, K.-V. (1994) Transactivation of the human multidrug resistance (MDRI) gene promoter by p53 mutants. Oncol. Res., 6, 71-77.
    • (1994) Oncol. Res. , vol.6 , pp. 71-77
    • Nguyen, K.T.1    Liu, B.2    Ueda, K.3    Gottesman, M.M.4    Pastan, I.5    Chin, K.-V.6
  • 14
    • 0028939453 scopus 로고
    • Wild-type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line
    • Goldsmith, M.E., Gudas, J.M., Schneider, E. and Cowan, K.H. (1995) Wild-type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line. J. Biol. Chem., 270, 1894-1898.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1894-1898
    • Goldsmith, M.E.1    Gudas, J.M.2    Schneider, E.3    Cowan, K.H.4
  • 15
    • 0029587415 scopus 로고
    • The region 3′ to the major transcriptional start site of the MDRI downstream promoter mediates activation by a subset of mutant p53 proteins
    • Strauss, B.E. and Haas, M. (1995) The region 3′ to the major transcriptional start site of the MDRI downstream promoter mediates activation by a subset of mutant p53 proteins. Biochem. Biophys. Res. Commun., 217, 333-340.
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 333-340
    • Strauss, B.E.1    Haas, M.2
  • 18
    • 0029880959 scopus 로고    scopus 로고
    • Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations
    • Leveillard, T., Andera, L., Bissonnette, N., Schaeffer, L., Bracco, L., Egly, J.M. and Wasylyk, B. (1996) Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J., 15, 1615-1624.
    • (1996) EMBO J. , vol.15 , pp. 1615-1624
    • Leveillard, T.1    Andera, L.2    Bissonnette, N.3    Schaeffer, L.4    Bracco, L.5    Egly, J.M.6    Wasylyk, B.7
  • 20
    • 0029945772 scopus 로고    scopus 로고
    • Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2
    • Scherer, S.J., Welter, C., Zang, K.D. and Dooley, S. (1996) Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2. Biochem. Biophys. Res. Commun., 221, 722-728.
    • (1996) Biochem. Biophys. Res. Commun. , vol.221 , pp. 722-728
    • Scherer, S.J.1    Welter, C.2    Zang, K.D.3    Dooley, S.4
  • 21
    • 0030853074 scopus 로고    scopus 로고
    • Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts
    • Ford, J.M. and Hanawalt, P.C. (1997) Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J. Biol. Chem., 272, 28073-28080.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28073-28080
    • Ford, J.M.1    Hanawalt, P.C.2
  • 22
    • 0032552021 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents
    • 6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents. Oncogene, 17, 845-851.
    • (1998) Oncogene , vol.17 , pp. 845-851
    • Grombacher, T.1    Eichhorn, U.2    Kaina, B.3
  • 23
    • 0032535308 scopus 로고    scopus 로고
    • Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53
    • Wang, Q. and Beck, W.T. (1998) Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53. Cancer Res., 58, 5762-5769.
    • (1998) Cancer Res. , vol.58 , pp. 5762-5769
    • Wang, Q.1    Beck, W.T.2
  • 27
    • 0028123442 scopus 로고
    • The p53 gene and protein in human brain tumors
    • Louis, D.N. (1994) The p53 gene and protein in human brain tumors. J. Neuropathol. Exp. Neurol., 53, 11-21.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 11-21
    • Louis, D.N.1
  • 29
    • 0020517665 scopus 로고
    • Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study
    • Chang, C.H., Horton, J., Schoenfeld, D., Salazer, O., Perez Tamayo, R., Kramer, S., Weinstein, A., Nelson, J.S. and Tsukada, Y. (1983) Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study. Cancer, 52, 997-1007.
    • (1983) Cancer , vol.52 , pp. 997-1007
    • Chang, C.H.1    Horton, J.2    Schoenfeld, D.3    Salazer, O.4    Perez Tamayo, R.5    Kramer, S.6    Weinstein, A.7    Nelson, J.S.8    Tsukada, Y.9
  • 30
    • 0023829993 scopus 로고
    • Combined modality approach to treatment of malignant gliomas - Re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: A joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group
    • Nelson, D.F., Diener West, M., Horton, J., Chang, C.H., Schoenfeld, D. and Nelson, J.S. (1988) Combined modality approach to treatment of malignant gliomas - re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology Group. Natl Cancer Inst. Monogr., 6, 279-284.
    • (1988) Natl Cancer Inst. Monogr. , vol.6 , pp. 279-284
    • Nelson, D.F.1    Diener West, M.2    Horton, J.3    Chang, C.H.4    Schoenfeld, D.5    Nelson, J.S.6
  • 32
    • 0023108382 scopus 로고
    • Astrocytes induce blood-brain barrier properties in endothelial cells
    • Janzer, R.C. and Raff, M.C. (1987) Astrocytes induce blood-brain barrier properties in endothelial cells. Nature, 325, 253-257.
    • (1987) Nature , vol.325 , pp. 253-257
    • Janzer, R.C.1    Raff, M.C.2
  • 33
    • 0029885315 scopus 로고    scopus 로고
    • Wild-type p53 renders mouse astrocytes resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea despite the absence of a p53-dependent cell cycle arrest
    • Nutt, C.L., Chambers, A.F. and Cairncross, J.G. (1996) Wild-type p53 renders mouse astrocytes resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea despite the absence of a p53-dependent cell cycle arrest. Cancer Res., 56, 2748-2751.
    • (1996) Cancer Res. , vol.56 , pp. 2748-2751
    • Nutt, C.L.1    Chambers, A.F.2    Cairncross, J.G.3
  • 36
  • 37
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl Acad. Sci. USA, 87, 5368-5372.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 5368-5372
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 38
    • 0025941670 scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) cDNA in chinese hamster cells: The role of MGMT in protection against the genotoxic effects of alkylating agents
    • 6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. Carcinogenesis, 12, 1857-1867.
    • (1991) Carcinogenesis , vol.12 , pp. 1857-1867
    • Kaina, B.1    Fritz, G.2    Mitra, S.3    Coquerelle, T.4
  • 41
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • McCarthy, K.D. and De Vellis, J. (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol., 85, 890-902.
    • (1980) J. Cell Biol. , vol.85 , pp. 890-902
    • McCarthy, K.D.1    De Vellis, J.2
  • 42
    • 0027981995 scopus 로고
    • Rapid allelotype analysis of p53 knockout mice
    • Timme, T.L. and Thompson, T.C. (1994) Rapid allelotype analysis of p53 knockout mice. Biotechniques, 17, 460, 462-463.
    • (1994) Biotechniques , vol.17 , pp. 460
    • Timme, T.L.1    Thompson, T.C.2
  • 43
    • 0025571828 scopus 로고
    • 6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
    • 6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea. Cancer Commun., 2, 371-377.
    • (1990) Cancer Commun. , vol.2 , pp. 371-377
    • Dolan, M.E.1    Stine, L.2    Mitchell, R.B.3    Moschel, R.C.4    Pegg, A.E.5
  • 44
    • 0022556526 scopus 로고
    • 6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents
    • 6-alkylguanine pretreatment on the sensitivity of human colon tumor cells to the cytotoxic effects of chloroethylating agents. Cancer Res., 46, 4500-4504.
    • (1986) Cancer Res. , vol.46 , pp. 4500-4504
    • Dolan, M.E.1    Young, G.S.2    Pegg, A.E.3
  • 46
    • 0022389146 scopus 로고
    • A study of mitochondrial and nuclear transcription with cloned cDNA probes
    • Edwards, D.R. and Denhardt, D.T. (1985) A study of mitochondrial and nuclear transcription with cloned cDNA probes. Exp. Cell Res., 157, 127-143.
    • (1985) Exp. Cell Res. , vol.157 , pp. 127-143
    • Edwards, D.R.1    Denhardt, D.T.2
  • 47
    • 0022218334 scopus 로고
    • Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: Equivalence of one species to B2 repetitive elements
    • Edwards, D.R., Parfett, C.L.J. and Denhardt, D.T. (1985) Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol. Cell. Biol., 5, 3280-3288.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 3280-3288
    • Edwards, D.R.1    Parfett, C.L.J.2    Denhardt, D.T.3
  • 49
    • 0031003552 scopus 로고    scopus 로고
    • Transgenic mice with p53-responsive lacZ: P53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo
    • Komarova, E.A., Chernov, M.V., Franks, R., Wang, K., Armin, G., Zelnick, C.R., Chin, D.M., Bacus, S.S., Stark, G.R. and Gudkov, A.V. (1997) Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo. EMBO J., 16, 1391-1400.
    • (1997) EMBO J. , vol.16 , pp. 1391-1400
    • Komarova, E.A.1    Chernov, M.V.2    Franks, R.3    Wang, K.4    Armin, G.5    Zelnick, C.R.6    Chin, D.M.7    Bacus, S.S.8    Stark, G.R.9    Gudkov, A.V.10
  • 50
    • 0022506890 scopus 로고
    • Rapid chemosensitivity testing of human lung tumor cells using the MTT assay
    • Cole, S.P.C. (1986) Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother. Pharmacol., 17, 259-263.
    • (1986) Cancer Chemother. Pharmacol. , vol.17 , pp. 259-263
    • Cole, S.P.C.1
  • 51
    • 0022271990 scopus 로고
    • 6-methylguanine methyltransferase activity is increased in rat tissues by ionising radiation
    • 6-Methylguanine methyltransferase activity is increased in rat tissues by ionising radiation. Carcinogenesis, 6, 1699-1702.
    • (1985) Carcinogenesis , vol.6 , pp. 1699-1702
    • Margison, G.P.1    Butler, J.2    Hoey, B.3
  • 52
    • 0025055581 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity in fetal rat brain and liver and the induction of CNS tumours
    • 6-alkylguanine-DNA alkyltransferase activity in fetal rat brain and liver and the induction of CNS tumours. Carcinogenesis, 11, 219-222.
    • (1990) Carcinogenesis , vol.11 , pp. 219-222
    • Stammberger, I.1    Schmahl, W.2    Nice, L.3
  • 53
    • 0025767132 scopus 로고
    • 6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments
    • 6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. Mol. Cell. Biol., 11, 4660-4668.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4660-4668
    • Fritz, G.1    Tano, K.2    Mitra, S.3    Kaina, B.4
  • 55
    • 0027196815 scopus 로고
    • 6-alkylguanine-DNA-alkyltransferase mRNA and activity in mouse tissues
    • 6-alkylguanine-DNA-alkyltransferase mRNA and activity in mouse tissues. Carcinogenesis, 14, 679-683.
    • (1993) Carcinogenesis , vol.14 , pp. 679-683
    • Wilson, R.E.1    Hoey, B.2    Margison, G.P.3
  • 56
    • 0029803785 scopus 로고    scopus 로고
    • Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes
    • Grombacher, T., Mitra, S. and Kaina, B. (1996) Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes. Carcinogenesis, 17, 2329-2336.
    • (1996) Carcinogenesis , vol.17 , pp. 2329-2336
    • Grombacher, T.1    Mitra, S.2    Kaina, B.3
  • 57
    • 0028980765 scopus 로고
    • 6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor-derived cell lines
    • 6-methylguanine-DNA methyltransferase to resistance to 1,3-(2-chloroethyl)-1-nitrosourea in human brain tumor-derived cell lines. Mol. Carcinog., 13, 81-88.
    • (1995) Mol. Carcinog. , vol.13 , pp. 81-88
    • Bobola, M.S.1    Berger, M.S.2    Silber, J.R.3
  • 58
    • 0028980769 scopus 로고
    • 6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines
    • 6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines. Mol. Carcinog., 13, 70-80.
    • (1995) Mol. Carcinog. , vol.13 , pp. 70-80
    • Bobola, M.S.1    Blank, A.2    Berger, M.S.3    Silber, J.R.4
  • 59
    • 0029657595 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin
    • 6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin. Clin. Cancer Res., 2, 735-741.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 735-741
    • Bobola, M.S.1    Tseng, S.H.2    Blank, A.3    Berger, M.S.4    Silber, J.R.5
  • 61
    • 0033090363 scopus 로고    scopus 로고
    • Characterization of cellular pathways involved in glioblastoma response to the chemotherapeutic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) by gene expression profiling
    • Hun Rhee, C. Ruan, S., Chen, S., Chenchik, A., Levin, V.A., Yung, A.W.K., Fuller, G.N. and Zhang, W. (1999) Characterization of cellular pathways involved in glioblastoma response to the chemotherapeutic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) by gene expression profiling. Oncol. Rep., 6, 393-401.
    • (1999) Oncol. Rep. , vol.6 , pp. 393-401
    • Hun Rhee, C.1    Ruan, S.2    Chen, S.3    Chenchik, A.4    Levin, V.A.5    Yung, A.W.K.6    Fuller, G.N.7    Zhang, W.8


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