CD36 is a ditopic glycoprotein with the N-terminal domain implicated in intracellular transport

Biochemical and Biophysical Research Communications

Volumn 275, Issue 2, 2000, Pages 446-454

  Gruarin, Paola ^a   Thorne, Rick F ^b   Dorahy, Douglas J ^b   Burns, Gordon F ^b   Sitia, Roberto ^a   Alessio, Massimo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

CD36; Intracellular transport; Protein folding; Protein topology; Signal sequence

Indexed keywords

MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN; EXOCYTOSIS; HYDROPHOBICITY; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN TRANSPORT; SEQUENCE ANALYSIS;

EID: 0034726696     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3333     Document Type: Article

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5. Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site
6. Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36
7. Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL
8. Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake
9. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
10. Scavenger receptor in innate immunity
11. Regulation expression of CD36 during monocyte-to-macrophage differentiation: Potential role of CD36 in foam cell formation
12. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
13. Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion
14. Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding
15. CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction
16. CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
17. Identification of a platelet membrane glycoprotein as a falciparum malaria sequestration receptor
18. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes
19. Identification of an immunodominant functional domain on human CD36 antigen using human-mouse chimaeric proteins and homologue-replacement mutagenesis
20. Isolation and characterization of platelet glycoprotein IV (CD36)
21. Snmp-1, a novel membrane protein of olfactory neurons of the silk moth Antheraea polyphemus with homology to the CD36 family of membrane proteins
22. Cloning, sequencing, and expression of a cDNA encoding rat LIMP II, a novel 74-kDa lysosomal membrane protein related to the surface adhesion protein CD36
23. Analysis of CD36 binding domains: Ligand specificity controlled by dephosphorylation of an ectodomain
24. A carboxyl terminal truncation mutant of CD36 is secreted and binds thrombospondin: Evidence for a single transmembrane domain
25. CD36 is palmitoylated on both N- and C-terminal cytoplasmic tails
26. The biology and enzymology of eukaryotic protein acylation
27. Purification of the major substrate for palmitoylation in rat adipocytes: N-terminal homology with CD36 and evidence for cell surface acylation
28. Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07
29. Inhibition of Fc-receptor dependent platelet aggregation by monoclonal antibodies against the glycoprotein IIb-IIIa complex
30. Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa
31. CD36 forms covalently associated dimers and multimers in platelets and transfected COS-7 cells
32. pEF-BOS, a powerful mammalian expression vector
33. Formation of one or more intrachain disulphide bonds is required for the intracellular processing and transport of CD36
34. Synthesis, processing, and intracellular transport of CD36 during monocytic differentiation
35. CD36 folding revealed by conformational epitope expression is essential for cytoadherence of Plasmodium falciparum-infected red blood cells
36. Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36
37. Molecular chaperones and the biosynthesis of antigen receptors
38. Isolation of intracellular membranes by means of sodium carbonate treatment: Application to endoplasmic reticulum
39. Antigenic and functional differences in adhesion of Plasmodium falciparum-infected erythrocytes to human and bovine CD36
40. Brefeldin A: Insights into the control of membrane traffic and organelle structure