메뉴 건너뛰기




Volumn 13, Issue 11, 1999, Pages 1881-1892

Expression of Bcl-2-related genes in normal and AML progenitors: Changes induced by chemotherapy and retinoic acid

Author keywords

AML; Apoptosis; BAD; Bcl 2; Bcl X(L); Minimal residual disease

Indexed keywords

ANTINEOPLASTIC AGENT; CD34 ANTIGEN; CYTARABINE; MESSENGER RNA; PROTEIN BCL 2; PROTEIN BCL X; RETINOIC ACID;

EID: 0032721858     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401573     Document Type: Conference Paper
Times cited : (138)

References (49)
  • 1
    • 0031464448 scopus 로고    scopus 로고
    • Bcl-2 family proteins: Regulators of apoptosis and chemoresistance in hematologic malignancies
    • Reed JC. Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies. Semin Hematol 1997; 34:9-19.
    • (1997) Semin Hematol , vol.34 , pp. 9-19
    • Reed, J.C.1
  • 2
    • 0026781986 scopus 로고
    • Bcl-2 gene transfer increases relative resistance of S49.1 and WEH17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
    • Miyashita T, Reed JC. Bcl-2 gene transfer increases relative resistance of S49.1 and WEH17.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 1992; 52: 5407-5411.
    • (1992) Cancer Res , vol.52 , pp. 5407-5411
    • Miyashita, T.1    Reed, J.C.2
  • 3
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 1993; 81: 151-157.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 4
    • 0027196091 scopus 로고
    • Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
    • Walton WI, Whysong D, O'Connor PM, Hockenberry D, Korsmyer SJ, Kohn KW. Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. Cancer Res 1993; 53: 151-157.
    • (1993) Cancer Res , vol.53 , pp. 151-157
    • Walton, W.I.1    Whysong, D.2    O'Connor, P.M.3    Hockenberry, D.4    Korsmyer, S.J.5    Kohn, K.W.6
  • 5
    • 0027892521 scopus 로고
    • Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
    • Kamesaki S, Kamesaki H, Jorgensen TJ, Tanizawa A, Pommier Y, Cossman J. Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res 1993; 53: 4251-4256.
    • (1993) Cancer Res , vol.53 , pp. 4251-4256
    • Kamesaki, S.1    Kamesaki, H.2    Jorgensen, T.J.3    Tanizawa, A.4    Pommier, Y.5    Cossman, J.6
  • 7
    • 0028060247 scopus 로고
    • Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression
    • Kitada S, Takayama S, DeRiel K, Tanaka S, Reed JC. Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression. Antisense Res Dev 1994; 4: 71-79.
    • (1994) Antisense Res Dev , vol.4 , pp. 71-79
    • Kitada, S.1    Takayama, S.2    DeRiel, K.3    Tanaka, S.4    Reed, J.C.5
  • 8
    • 0028284281 scopus 로고
    • Effects of Bcl-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells
    • Campos L, Sabido O, Rouault J-P, Guyotat D. Effects of Bcl-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells. Blood 1994; 84: 595-600.
    • (1994) Blood , vol.84 , pp. 595-600
    • Campos, L.1    Sabido, O.2    Rouault, J.-P.3    Guyotat, D.4
  • 10
    • 0029157380 scopus 로고
    • Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells
    • Teixeira C, Reed JC, Pratt MAC. Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 protooncogene expression in human breast cancer cells. Cancer Res 1995; 55: 3902-3907.
    • (1995) Cancer Res , vol.55 , pp. 3902-3907
    • Teixeira, C.1    Reed, J.C.2    Pratt, M.A.C.3
  • 11
    • 8944230657 scopus 로고    scopus 로고
    • Overexpression of the death-promoting gene bax-a which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice
    • Bargou RC, Wagener C, Bommert K, Mapara MY, Daniel PT, Arnold W, Dietel M, Guski H, Feller A, Royer HD, Dorken B. Overexpression of the death-promoting gene bax-a which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice. J Clin Invest 1996; 97: 2651-2659.
    • (1996) J Clin Invest , vol.97 , pp. 2651-2659
    • Bargou, R.C.1    Wagener, C.2    Bommert, K.3    Mapara, M.Y.4    Daniel, P.T.5    Arnold, W.6    Dietel, M.7    Guski, H.8    Feller, A.9    Royer, H.D.10    Dorken, B.11
  • 12
    • 0028979438 scopus 로고
    • Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis
    • Sumantran VN, Ealogeva MW, Nunez G, Clarke MF, Wicha MS. Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res 1995; 55: 2507-2510.
    • (1995) Cancer Res , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealogeva, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 14
    • 0028326980 scopus 로고
    • Cloning and sequencing of cDNA encoding rat bcl-2 protein
    • Sato T, Irie S, Krajewski S, Reed JC. Cloning and sequencing of cDNA encoding rat bcl-2 protein. Gene 1994; 140: 291-292.
    • (1994) Gene , vol.140 , pp. 291-292
    • Sato, T.1    Irie, S.2    Krajewski, S.3    Reed, J.C.4
  • 16
    • 0029964257 scopus 로고    scopus 로고
    • Taxol induces bcl-2 phosphorylation and death of prostate cancer cells
    • Haldar S, Chintapalli J, Croce CM. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res 1996; 56: 1851-1854.
    • (1996) Cancer Res , vol.56 , pp. 1851-1854
    • Haldar, S.1    Chintapalli, J.2    Croce, C.M.3
  • 17
    • 0028972011 scopus 로고
    • Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 transduction pathway
    • Blagosklonny M, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J, Neckers L. Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 transduction pathway. Cancer Res 1995; 55: 4623-4626.
    • (1995) Cancer Res , vol.55 , pp. 4623-4626
    • Blagosklonny, M.1    Schulte, T.W.2    Nguyen, P.3    Mimnaugh, E.G.4    Trepel, J.5    Neckers, L.6
  • 18
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL
    • Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL. Cell 1996; 87: 619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 19
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
    • Wang H-G, Takayama S, Rapp UR, Reed JC Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci USA 1996; 93: 7063-7068.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7063-7068
    • Wang, H.-G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4
  • 21
    • 0029942921 scopus 로고    scopus 로고
    • The p53-binding protein 53BP2 also interacts with Bcl-2 and impedes cell cycle progression at G2/M
    • Naumovski L, Cleary ML. The p53-binding protein 53BP2 also interacts with Bcl-2 and impedes cell cycle progression at G2/M. Mol Cell Biol 1996; 16: 3884-3892.
    • (1996) Mol Cell Biol , vol.16 , pp. 3884-3892
    • Naumovski, L.1    Cleary, M.L.2
  • 22
    • 15844397398 scopus 로고    scopus 로고
    • Diminished cell proliferation associated with the death-protective activity of Bcl-2
    • Borner C. Diminished cell proliferation associated with the death-protective activity of Bcl-2. J Biol Chem 1996; 271: 12695-12698.
    • (1996) J Biol Chem , vol.271 , pp. 12695-12698
    • Borner, C.1
  • 23
    • 0029938724 scopus 로고    scopus 로고
    • Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism tor inhibition of programmed cell death
    • Mazel S, Burtrum D, Petrie HT. Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism tor inhibition of programmed cell death. J Exp Med 1996; 183: 2219-2226.
    • (1996) J Exp Med , vol.183 , pp. 2219-2226
    • Mazel, S.1    Burtrum, D.2    Petrie, H.T.3
  • 24
    • 0029843941 scopus 로고    scopus 로고
    • Cross talk between cell death and cell cycle progression. BCL-2 regulates NFAT-mediated activation
    • Linette GP, Li Y, Roth K, Korsmeyer SJ. Cross talk between cell death and cell cycle progression. BCL-2 regulates NFAT-mediated activation. Proc Natl Acad Sci USA 1996; 93: 9545-9552.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9545-9552
    • Linette, G.P.1    Li, Y.2    Roth, K.3    Korsmeyer, S.J.4
  • 25
    • 0030794452 scopus 로고    scopus 로고
    • The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
    • Huang D, O'Reilly L, Strasser A, Cory S. The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J 1997; 16: 4628-4638.
    • (1997) EMBO J , vol.16 , pp. 4628-4638
    • Huang, D.1    O'Reilly, L.2    Strasser, A.3    Cory, S.4
  • 26
    • 0029156492 scopus 로고
    • Primitive human hematopoietic precursors express Bcl-x but not Bcl-2
    • Park JR, Bernstein ID, Hockenberry DM. Primitive human hematopoietic precursors express Bcl-x but not Bcl-2. Blood 1995; 86: 868-876.
    • (1995) Blood , vol.86 , pp. 868-876
    • Park, J.R.1    Bernstein, I.D.2    Hockenberry, D.M.3
  • 27
    • 0028881958 scopus 로고
    • Comparative quantitative expression of bcl-2 by normal and leukaemic myeloid cells
    • Bradbury DA, Russel NH. Comparative quantitative expression of bcl-2 by normal and leukaemic myeloid cells. Br J Haematol 1995; 91: 374-379.
    • (1995) Br J Haematol , vol.91 , pp. 374-379
    • Bradbury, D.A.1    Russel, N.H.2
  • 28
    • 0029111391 scopus 로고
    • Bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukemia
    • Porwit MacDonald A, Ivory K, Wilkinson S, Wheayley K, Wong L, Janossy G. Bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukemia. Leukemia 1995; 9: 1191-1196.
    • (1995) Leukemia , vol.9 , pp. 1191-1196
    • Porwit MacDonald, A.1    Ivory, K.2    Wilkinson, S.3    Wheayley, K.4    Wong, L.5    Janossy, G.6
  • 31
    • 0029846602 scopus 로고    scopus 로고
    • Association of bcl-2, bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia
    • Stoetzer OJ, Nussler V, Darsow M, Gullis E, Pelka-Fleischer R, Scheel U, Wilmanns W. Association of bcl-2, bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia. Leukemia 1996; 10 (Suppl. 3): S18-S22.
    • (1996) Leukemia , vol.10 , Issue.SUPPL. 3
    • Stoetzer, O.J.1    Nussler, V.2    Darsow, M.3    Gullis, E.4    Pelka-Fleischer, R.5    Scheel, U.6    Wilmanns, W.7
  • 32
    • 0031889769 scopus 로고    scopus 로고
    • High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia
    • Karakas T, Maurer U, Weidmann E, Miething CC. High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia. Ann Oncol 1998; 9: 159-165.
    • (1998) Ann Oncol , vol.9 , pp. 159-165
    • Karakas, T.1    Maurer, U.2    Weidmann, E.3    Miething, C.C.4
  • 33
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge SJ. Cell cycle checkpoints: preventing an identity crisis. Science 1996; 274: 1664-1667.
    • (1996) Science , vol.274 , pp. 1664-1667
    • Elledge, S.J.1
  • 35
    • 0032523945 scopus 로고    scopus 로고
    • Modulation of bcl-2 protein levels by an intracellular anti-bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7
    • Piche A, Grim J, Rancourt C, Gomez-Navarro J, Reed JC, Curiel DT. Modulation of bcl-2 protein levels by an intracellular anti-bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7. Cancer Res 1998; 58: 2134-2140.
    • (1998) Cancer Res , vol.58 , pp. 2134-2140
    • Piche, A.1    Grim, J.2    Rancourt, C.3    Gomez-Navarro, J.4    Reed, J.C.5    Curiel, D.T.6
  • 37
    • 0028064668 scopus 로고
    • Sensitive detection and enumeration of CD34+ cells in peripheral and cord blood by flow cytometry
    • Sutherland DR, Keating A, Nayar R, Anania S, Stewart AK. Sensitive detection and enumeration of CD34+ cells in peripheral and cord blood by flow cytometry. Exp Hematol 1994; 22: 1003-1010.
    • (1994) Exp Hematol , vol.22 , pp. 1003-1010
    • Sutherland, D.R.1    Keating, A.2    Nayar, R.3    Anania, S.4    Stewart, A.K.5
  • 38
    • 0030780127 scopus 로고    scopus 로고
    • Minimal residual disease in acute rnyelogenous leukemia and myelodysplastic syndromes: A follow-up of patients in clinical remission
    • Engel H, Goodacre A, Keyhani A, Jiang S, Van NT, Kimmel M, Sanchez-Williams G, Andreeff M. Minimal residual disease in acute rnyelogenous leukemia and myelodysplastic syndromes: a follow-up of patients in clinical remission. Br J Haematot 1997; 99: 64-75.
    • (1997) Br J Haematot , vol.99 , pp. 64-75
    • Engel, H.1    Goodacre, A.2    Keyhani, A.3    Jiang, S.4    Van, N.T.5    Kimmel, M.6    Sanchez-Williams, G.7    Andreeff, M.8
  • 40
    • 0029045784 scopus 로고
    • Reduced expression of proapoptotic gene BAX is associated with poor response rates to com-bination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
    • Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, Nordling S, Reed JC. Reduced expression of proapoptotic gene BAX is associated with poor response rates to com-bination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res 1995; 55: 4471-4478.
    • (1995) Cancer Res , vol.55 , pp. 4471-4478
    • Krajewski, S.1    Blomqvist, C.2    Franssila, K.3    Krajewska, M.4    Wasenius, V.M.5    Niskanen, E.6    Nordling, S.7    Reed, J.C.8
  • 41
    • 4243783793 scopus 로고    scopus 로고
    • Proliferation and apoptosis regulating proteins and cytogenetics predict prognosis in acute myelogenous leukemia
    • Kornblau SM, Thall P, Estrov Z, Kantarjian H, Estey E, Andreeff M. Proliferation and apoptosis regulating proteins and cytogenetics predict prognosis in acute myelogenous leukemia. Blood 1997; 90 (Suppl. 1): 308, 71a.
    • (1997) Blood , vol.90 , Issue.SUPPL. 1 , pp. 308
    • Kornblau, S.M.1    Thall, P.2    Estrov, Z.3    Kantarjian, H.4    Estey, E.5    Andreeff, M.6
  • 42
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997; 90: 405.
    • (1997) Cell , vol.90 , pp. 405
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 44
    • 0032543578 scopus 로고    scopus 로고
    • The kit receptor promotes cell survival via activation of Pl 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136
    • Blume-Jensen P, Janknecht R, Hunter T. The kit receptor promotes cell survival via activation of Pl 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136. Curr Biol 1998; 8: 779-782.
    • (1998) Curr Biol , vol.8 , pp. 779-782
    • Blume-Jensen, P.1    Janknecht, R.2    Hunter, T.3
  • 45
    • 85038133183 scopus 로고    scopus 로고
    • Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize AML to cytosine-arabinoside, and induce apoptosis independent of other anti-apoptotic proteins
    • submitted
    • Konopleva M, Tari A, Estrov Z, Harris D, Xie Z, Zhao S, Lopez-Berestein G, Andreeff M. Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize AML to cytosine-arabinoside, and induce apoptosis independent of other anti-apoptotic proteins. Blood (submitted).
    • Blood
    • Konopleva, M.1    Tari, A.2    Estrov, Z.3    Harris, D.4    Xie, Z.5    Zhao, S.6    Lopez-Berestein, G.7    Andreeff, M.8
  • 47
    • 0033028310 scopus 로고    scopus 로고
    • Regulatory pathways in programmed cell death
    • Konopleva M, Andreeff M. Regulatory pathways in programmed cell death. Cancer Mol Biol 1999; 6: 1229-1260.
    • (1999) Cancer Mol Biol , vol.6 , pp. 1229-1260
    • Konopleva, M.1    Andreeff, M.2
  • 48
    • 0000984457 scopus 로고    scopus 로고
    • All-traps retinoic acid (ATRA) may improve results of chemotherapy in poor prognosis non-APL AML and MDS: A randomized study
    • Estey E, Beran M, Pierce S, Kantarjian H, Keating M. All-traps retinoic acid (ATRA) may improve results of chemotherapy in poor prognosis non-APL AML and MDS: a randomized study. Blood 1997; 90 (Suppl. 1): 1851, 416a.
    • (1997) Blood , vol.90 , Issue.SUPPL. 1 , pp. 1851
    • Estey, E.1    Beran, M.2    Pierce, S.3    Kantarjian, H.4    Keating, M.5
  • 49
    • 0033560841 scopus 로고    scopus 로고
    • Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin ± all-trans retionic acid ± granulocyte-colony stimulating factor in poor prognosis newly-diagnosed non-APL AML and MDS
    • Estey EH, Thall PF, Pierce S, Cortes J, Beran M, Kantarjian H, Keating MJ, Andreeff M, Freireich E. Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin ± all-trans retionic acid ± granulocyte-colony stimulating factor in poor prognosis newly-diagnosed non-APL AML and MDS. Blood 1999; 93: 2478-2484.
    • (1999) Blood , vol.93 , pp. 2478-2484
    • Estey, E.H.1    Thall, P.F.2    Pierce, S.3    Cortes, J.4    Beran, M.5    Kantarjian, H.6    Keating, M.J.7    Andreeff, M.8    Freireich, E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.