The conformation of bound GMPPNP suggests a mechanism for gating the active site of the SRP GTPase

Structure

Volumn 9, Issue 9, 2001, Pages 859-867

  Padmanabhan, Savita ^a   Freymann, Douglas M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Ffh; GMPPNP; GTPase; NG domain; SRP; X ray crystallography

Indexed keywords

BACTERIAL ENZYME; DOCKING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE DERIVATIVE; MAGNESIUM; PHOSPHATE; SIGNAL RECOGNITION PARTICLE;

AMINO ACID SEQUENCE; ARTICLE; BETA CHAIN; BINDING SITE; CHANNEL GATING; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; THERMUS AQUATICUS;

AMINO ACID MOTIFS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; GTP PHOSPHOHYDROLASES; GUANYLYL IMIDODIPHOSPHATE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; SIGNAL RECOGNITION PARTICLE; THERMUS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PROKARYOTA; THERMUS AQUATICUS;

EID: 0034808131     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00641-4     Document Type: Article

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