First-pass midazolam metabolism catalyzed by 1α,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 2, 1999, Pages 1134-1142

  Fisher, Jeannine M ^d   Wrighton, Steven A ^d   Watkins, Paul B ^c   Schmiedlin Ren, Phyllissa ^c   Calamia, Justina C ^a   Shen, Danny D ^a   Kunze, Kent L ^b   Thummel, Kenneth E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CYCLOSPORIN; CYTOCHROME P450; MIDAZOLAM; SAQUINAVIR;

CONFERENCE PAPER; DOSE RESPONSE; DRUG ABSORPTION; DRUG PENETRATION; DRUG UPTAKE; FIRST PASS EFFECT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BIOTRANSFORMATION; BLOOD PROTEINS; BLOTTING, WESTERN; CACO-2 CELLS; CALCITRIOL; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRIC CONDUCTIVITY; EXTRACELLULAR SPACE; HUMANS; KINETICS; MIDAZOLAM; MIXED FUNCTION OXYGENASES; PERMEABILITY; REPRODUCIBILITY OF RESULTS;

EID: 0032903499     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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