Deletion of a direct repeat element has no effect on Igf2 and H19 imprinting

Mammalian Genome

Volumn 12, Issue 11, 2014, Pages 873-876

  Reed, Michael R ^a   Riggs, Arthur D ^a   Mann, Jeffrey R ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE; SOMATOMEDIN B;

ALLELE; ANIMAL CELL; ARTICLE; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENOME IMPRINTING; METHYLATION; MOUSE; NONHUMAN; NUCLEOTIDE REPEAT; TRANSGENE;

EID: 0034751659     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-001-2027-9     Document Type: Article

References (35)

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3. Peg1/Mest locates distal to the currently defined imprinting region on mouse proximal chromosome 6 and identifies a new imprinting region affecting growth
4. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
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6. Cytosine methylation and the unequal developmental potentials of the oocyte and sperm genomes
7. Creation of genomic methylation patterns
8. Aquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis
9. Deletion of a silencer element disrupts H19 imprinting independently of a DNA methylation epigenetic switch
10. Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting
11. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
12. A transcriptional insulator at the imprinted H19/Igf2 locus
13. The 5′ flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication
14. Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
15. Methylated DNA sequences in genomic imprinting
16. Mouse U2af1-rs1 is a neomorphic imprinted gene
17. Characteristics of imprinted genes
18. Absence of imprinting in U2AFBPL, a human homologue of the imprinted mouse gene U2afbp-rs
19. A direct repeat sequence at the Rasgrf1 locus and imprinted expression
20. Nucleic acid hybridizations with positive charge-modified nylon membrane
21. Novel neural network algorithms for improved eukaryotic promoter site recognition
22. Large scale sequencing specific neural networks for promoter and splice site recognition
23. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission
24. Enhancer competition between H19 and Igf2 does not mediate their imprinting
25. RNA-mediated gene duplication: The rat preproinsulin I gene is a functional retroposon
26. H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19
27. Role of a 461-bp G-rich repetitive element in H19 transgene imprinting
28. Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines
29. Allele-specific expression and total expression levels of imprinted genes during early mouse development: Implications for imprinting mechanisms
30. Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function
31. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
32. A 5′ 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development
33. The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development
34. Inner ear defects induced by null mutation of the isk gene
35. Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice