Characterization of NF-κB expression in Hodgkin's disease: Inhibition of constitutively expressed NF-κB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells

Modern Pathology

Volumn 14, Issue 4, 2001, Pages 297-310

  Izban, Keith F ^a   Ergin, Melek ^a   Huang, Qin ^a   Qin, Jian Zhong ^a   Martinez, Robert L ^a   Schnitzer, Bertram ^b   Ni, Hongyu ^a   Nickoloff, Brian J ^a   Alkan, Serhan ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Gliotoxin; MG132; P65(Rel A); Rel NF B transcription factors; Ubiquitin proteasome

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CASPASE INHIBITOR; GLIOTOXIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; VIRUS VECTOR; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CASP3 PROTEIN, HUMAN; CASPASE; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; ENZYME INHIBITOR; LEUPEPTIN; MULTIENZYME COMPLEX; OLIGOPEPTIDE; PROTEASOME; TRANSCRIPTION FACTOR RELA; UBIQUITIN;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HODGKIN DISEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REED STERNBERG CELL; ADENOVIRUS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; GENE VECTOR; GENETICS; IMMUNOHISTOCHEMISTRY; LEUKEMIA CELL LINE; METABOLISM; PATHOLOGY;

ADENOVIRIDAE; APOPTOSIS; CASPASE 3; CASPASES; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLOW CYTOMETRY; GENETIC VECTORS; GLIOTOXIN; HODGKIN DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; JURKAT CELLS; LEUPEPTINS; MULTIENZYME COMPLEXES; NF-KAPPA B; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; REED-STERNBERG CELLS; TRANSCRIPTION FACTOR RELA; UBIQUITINS;

EID: 0034744586     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880306     Document Type: Article

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