CD95 (Fas)-induced caspase-mediated proteolysis of NF-κB

Cancer Research

Volumn 58, Issue 5, 1998, Pages 882-886

  Ravi, Rajani ^a   Bedi, Asheesh ^a   Fuchs, Ephraim J ^a   Bedi, Atul ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE REPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASES; CYSTEINE ENDOPEPTIDASES; HUMANS; JURKAT CELLS; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 0032032627     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Fuchs, E. J. Cellular immunology. In: J. F. Hoffman and J. D. Jamieson (eds.), Handbook of Physiology, pp. 743-787. New York: Oxford University Press, Inc., 1997.
2. Allison, J. P., and Krummel, M. F. The yin and yang of T cell costimulation. Science (Washington DC), 270: 932-933, 1995.
3. Lenschow, D. J., Walunas, T. L., and Bluestone, J. A. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol., 14: 233-258, 1996.
4. Nagata, S. Apoptosis by death factor. Cell, 88: 355-365, 1997.
5. Wong, B., and Choi, Y. Pathways leading to cell death in T cells. Curr. Opin. Immunol., 9: 365-370, 1997.
6. Winoto, A. Cell death in the regulation of immune responses. Curr. Opin. Immunol., 9: 358-364, 1997.
7. Barnes, P. J., and Karin, M. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med., 336: 1066-1071, 1997.
8. Thanos, D., and Maniatis, T. NF-κB. A lesson in family values. Cell, 80: 529-532, 1995.
9. Baldwin, A. S. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol., 14: 649-681, 1996.
10. Baeuerle, P. A., and Baltimore, D. NF-κB: ten years after. Cell, 87: 13-20, 1996.
11. Ghosh, S., and Baltimore, D. Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature (Lond.), 344: 678-682, 1990.
12. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. Control of IκBα proteolysis by site-specific, signal-induced phosphorylation. Science (Washington DC), 267: 1485-1488, 1995.
13. Whiteside, S., Enst, M., LeBail, O., Laurent Winter, C., Rice, N., and Israel, A. N- and C-terminal sequences control the degradation of MAD3/IκBα in response to inducers of NF-κB activity. Mol. Cell. Biol., 15: 5339-5345, 1995.
14. Harhaj, E. W., Maggirwar, S. B., Good, L., and Sun, S-C. CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers. Mol. Cell. Biol., 16: 6736-6743, 1996.
15. Lai, J-H., and Tan, T-H. CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin. J. Biol. Chem., 269: 30077-30080, 1994.
16. Ju, S. T., Panka, D. J., Cui, H., Ettinger, R., el-Kathib, M., Sherr, D. H., Stanger, B. Z., and Marshak-Rothstein, A. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature (Lond.), 373: 444-448, 1995.
17. Dhein, J., Walczak, H., Baumler, C., Debatin, K. M., and Krammer, P. H. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature (Lond.), 373: 438-441, 1995.
18. Brunner, T., Mogil, R. J., LaFace, D., Yoo, N. J., Mahboubi, A., Echeverri, F., Martin, S. J., Force, W. R., Lynch, D. H., Ware, C. F., et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature (Lond.), 373: 441-444, 1995.
19. Nagata, S., and Golstein, P. The Fas death factor. Science (Washington DC), 267: 1449-1456, 1995.
20. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the C95 (Fas/APO-1) death-inducing signalling complex. Cell, 85: 817-827, 1996.
21. Enari, M., Hug, H., and Nagata, S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (Lond.), 380: 723-726, 1996.
22. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Rojir, S. M., Smulson, M. E., Yamin, T-T., Yu, V. L., and Miller, D. K. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature (Lond.), 376: 37-43, 1995.
23. Nolan, G. P., Ghosh, S., Liou, H-C., Tempst, P., and Baltimore, D. DNA binding and IκBα inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell, 64: 961-969, 1991.
24. Ghosh, S., Gifford, A. M., Riviere, L. R., Tempst, P., Nolan, G. P., and Baltimore, D. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell, 62: 1019-1029, 1990.
25. Wang, C., Mayo, M. W., and Baldwin, A., Jr. TNF and cancer therapy-induced apoptosis. Potentiation by inhibition of NF-κB. Science (Washington DC), 274: 784-787, 1996.
26. Van Antwerp, D. J., Martin, S. J., Kafri, T., Green, D. R., and Verma, I. M. Suppression of TNF-α-induced apoptosis by NF-κB. Science (Washington DC), 274: 787-789, 1996.
27. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11: 1475-1489, 1983.
28. Beg, A. A., and Baltimore, D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science (Washington DC), 274: 782-784, 1996.
29. Liu, Z-G., Hsu, H., Goeddel, D., and Karin, M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell, 87: 565-576, 1996.
30. White, D. W., and Gilmore, T. D. Bcl-2 and CrmA have different effects on transformation, apoptosis and the stability of IκBα in chicken spleen cells transformed by temperature-sensitive v-Rel oncoproteins. Oncogene, 13: 891-899, 1996.
31. Rothe, M., Wong, S. C., Henzel, W. J., and Goeddel, D. V. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor. Cell, 78: 681-692, 1994.