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Biochemical and Biophysical Research Communications

Volumn 278, Issue 3, 2000, Pages 590-598

GPI 6150 prevents H2O2 cytotoxicity by inhibiting poly(ADP-ribose) polymerase

(6) Zhang, Jie a Lautar, Susan a Huang, Shirley a Ramsey, Cynthia a Cheung, Anissa a Li, Jia He a

a GUILFORD PHARMACEUTICALS INC (United States)

Author keywords

NAD+ depletion; Reactive oxygen species damage; Small molecule PARP inhibitor; Specificity of GPI 6150

Indexed keywords

1,11B DIHYDRO[2H]BENZOPYRANO[4,3,2 DE]ISOQUINOLIN 3 ONE; 3 AMINOBENZAMIDE; BENZAMIDE; BENZOPYRAN DERIVATIVE; GPI 6150; HYDROGEN PEROXIDE; ISOQUINOLINE DERIVATIVE; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTHRITIS; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; DRUG POTENCY; HEART MUSCLE ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; STREPTOZOCIN DIABETES;

ANIMALIA; RODENTIA;

EID: 0034735993 PISSN: 0006291X EISSN: None Source Type: Journal
DOI: 10.1006/bbrc.2000.3816 Document Type: Article

Times cited : (50)

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