Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development

European Journal of Pharmacology

Volumn 351, Issue 3, 1998, Pages 377-382

  Endres, Matthias ^a   Scott, Gwen S ^b   Salzman, Andrew L ^b   Kun, Ernest ^c   Moskowitz, Michael A ^a   Szabó, Csaba ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c SAN FRANCISCO STATE UNIVERSITY   (United States)

Author keywords

Glia; Inflammation; Nitric oxide (NO); Reperfusion; Superoxide

Indexed keywords

5 IODO 6 AMINO 1,2 BENZOPYRONE; COUMARIN; ENZYME INHIBITOR; LACTATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXYNITRITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ELECTRON TRANSPORT; GLIA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; STROKE;

ANIMALS; CELL DEATH; CEREBRAL INFARCTION; COUMARINS; ENZYME INHIBITORS; ISCHEMIA; L-LACTATE DEHYDROGENASE; MALE; MICE; MITOCHONDRIA; NEUROGLIA; NEURONS; NITRATES; POLY(ADP-RIBOSE) POLYMERASES; RATS; TUMOR CELLS, CULTURED;

EID: 0031856719     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00381-1     Document Type: Article

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