Protection against hypoxia-reoxygenation in the absence of poly (ADP ribose) synthetase in isolated working hearts

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 1, 1999, Pages 297-303

  Grupp, Ingrid L ^a   Jackson, Traci M ^a   Hake, Paul ^b   Grupp, Gunther ^a   Szabó, Csaba ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Cardiac myocytes; Nitric oxide; Peroxynitrite; Reperfusion; Superoxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROXYL RADICAL; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PEROXYNITRITE;

ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; HEART AFTERLOAD; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART PRELOAD; HEART PROTECTION; HEART VENTRICLE PRESSURE; HYPOXIA; ISOLATED HEART; MOUSE; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; REPERFUSION INJURY; TIME; VENOUS RETURN;

EID: 0032990891     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0864     Document Type: Article

References (40)

1. Abd-Elfattah AS, Jessen ME, Hanan SA, Tuchy G, Wechsler AS, 1990. Is adenosine 5′-triphosphate derangement or free-radical-mediated injury the major cause of ventricular dysfunction during reperfusion? role of adenine nucleoside transport in myocardial reperfusion injury. Circulation 82: IV341-IV350.
2. Acad BA, Guggenheimer E, Sonn J, Kedem J, 1983. Differential effects of various inotropic agents on the intracellular NADH redox level in the in vivo dog heart. J Cardiovasc Pharmacol 5: 284-290.
3. Berger NA, 1991. Oxidant-induced cytotoxicity: A challenge for metabolic modulation. Am J Respir Cell Mol Biol 4: 1-3.
4. Bromme HJ, Holtz J, 1996. Apoptosis in the heart: When and why? Mol Cell Biochem 164: 261-275.
5. Chu G, Luo W, Slack JP, Tilgman C, Sweet WE, Spindler M, Saupe KW, Boivin GP, Moravec CS, Matlib MA, Grupp IL, Ingwall JS, Kranias EG, 1996. Compensatory mechanisms associated with the hyperdynamic function of phospholamban deficient mouse hearts. Circ Res 78: 1064-1076.
6. Dhar PK, Grupp IL, Schwartz A, Grupp G, Matlib MA, 1996. Reduction in carnitine content by inhibition of its biosynthesis results in protection of isolated guinea pig hearts against hypoxic damage. J Cardiovasc Pharmacol Ther 1: 235-242.
7. Doherty JC, Kuzio B, Bowes J, Thiemermann C, 1998. Protective effects of poly (ADP-ribose) synthetase inhibition during reperfusion of the ischemic myocardium. Naunyn-Schmiedeberg's Arch Pharmacol 358 (Suppl. 1): R626.
8. Eliasson MJL, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang ZQ, Dawson TM, Snyder SH, Dawson VL, 1997. Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nature Med 3: 1089-1095.
9. Endres M, Wang Z-Q, Namura S, Waeber C, Moskowitz MA, 1997. Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. J Cerebr Blood Flow Metab 17: 1143-1151.
10. Gilad E, Zingarelli B, Salzman AL, Szabó C, 1997. Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro. J Mol Cell Cardiol 29: 2585-2597.
11. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL, 1994. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 94: 1621-1628.
12. Grupp IL, Subramaniam A, Hewett TE, Robbins J, Grupp G, 1993. Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations. Am J Physiol 265: H1401-1410.
13. Hare JM, Colucci WS, 1995. Role of nitric oxide in the regulation of myocardial function. Prog Cardiovasc Dis 38: 155-166.
14. Heller B, Wang ZQ, Wagner EF, Radons J, Burkl A, Fehsel K, Burkart V, Kolb H, 1995. Inactivation of the poly(ADP-ribose)polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J Biol Chem 270: 11176-11180.
15. Humphrey SM, Cartner LA, Holliss DG, 1987. Critical early metabolic changes associated with myocardial recovery or failure after total ischaemia in the rat heart. Basic Res Cardiol 82: 304-316.
16. Ishida H, Ichimori K, Hirota Y, Fukaori M, Nakazawa H, 1996. Peroxynitrite-induced cardiac myocyte injury. Free Rad Biol Med 20: 343-350.
17. Kajstura J, Cheng W, Reiss K, Clark WA, Sonnenblick EH, Krajewski S, Reed JC, Olivetti G, Anversa P, 1996. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 74: 86-107.
18. Kelm M, Schafer S, Dahmann R, Dolu B, Perings S, Decking UK, Schrader J, Strauer BE, 1997. Nitric oxide induced contractile dysfunction is related to a reduction in myocardial energy generation. Cardiovasc Res 36: 185-194.
19. Kirshenbaum LA, Singal PK, 1992. Changes in anti-oxidant enzymes in isolated cardiac myocytes subjected to hypoxia-reoxygenation. Lab Invest 67: 796-803.
20. Le Rhun YL, Kirkland JB, Shah GM, 1998. Cellular responses to DNA damage in the absence of poly ( ADP-ribose) polymerase. Biochem Biophys Res Commun 245: 1-10.
21. Ma XL, Lopez BL, Liu GL, Christopher TA, Ischiropoulos H, 1997. Peroxynitrite aggravates myocardial reperfusion injury in the isolated perfused rat heart. Cardiovasc Res 36: 195-204.
22. Mccord JM, 1988. Free radicals and myocardial ischaemia: Overview and outlook. Free Rad Biol Med 4: 9-14.
23. Nicholson DW, Thornberry NA, 1997. Caspases: Killer proteases. Trends Biochem Sci 22: 299-306.
24. Quaife RA, Kohmoto O, Barry WH, 1991. Mechanisms of reoxygenation injury in cultured ventricular myocytes. Circulation 83: 566-577.
25. Schulz R, Wambolt R, 1995. Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischemia-reperfusion injury. Cardiovasc Res 30: 432-439.
26. Steenbergen C, Murphy E, Watts JA, London RE, 1990. Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart. Circ Res 66: 135-146.
27. Szabó C, 1998. Role of poly (ADP-ribose) synthetase in inflammation. Eur J Pharmacol 350: 1-19.
28. Szabó C, Dawson VL, 1998. Role of poly (ADP-ribose) synthetase activation in inflammation and reperfusion injury. Trends Pharmacol Sci 19: 287-298.
29. Szabó C, Lim LH, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M, 1997. Inhibition of poly (ADP-ribose) synthetase exerts anti-inflammatory effects and inhibits neutrophil recruitment. J Exp Med 186: 1041-1049.
30. Szabó C, Virág L, Cuzzocrea S, Scott GJ, Hake P, O'Connor MP, Zingarelli B, Salzman AL, Kun E, 1998. Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly (ADP-ribose) synthetase. Proc Natl Acad Sci USA 95: 3867-3872.
31. Villa LM, Salas E, Darley-Usmar V, Radomski M, Moncada S, 1994. Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc Natl Acad Sci USA 91: 12383-12387.
32. 2+-ATPase by peroxynitrite. Free Rad Res 24: 243-259.
33. Virág L, Scott GS, Marmer D, Salzman AL, Szabó C, 191998a. Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly-(ADP-ribose) synthetase (PARS) activation. Immunology 94: 345-355.
34. Virág L, Salzman AL, Szabó C, 1998b. Poly (ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J Immunol 161: 3753-3759.
35. Wang P, Zweier JL, 1996. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. J Biol Chem 271: 29223-29230.
36. Wang ZQ, Auer B, StingL L, BergHammer H, HaiDacher D, Schweiger M, Wagner EF, 1995. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev 9: 510-520.
37. Wang Z-Q, Stingl L, Morrison C, Jantsch M, Los M, Schulze-Osthoff K, Wagner EF, 1997. PARP is important for genomic stability but dispensable in apoptosis. Genes Dev 11: 2347-2358.
38. Xie YW, Wolin MS, 1996. Role of nitric oxide and its interaction with superoxide in the suppression of cardiac muscle mitochondrial respiration. Circulation 94: 2580-2586.
39. Yaoita H, Ogawa K, Maehara K, Maruyama Y, 1998. Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor. Circulation 97: 276-281.
40. Zingarelli B, Salzman AL, Szabó C, 1998. Genetic disruption of poly (ADP ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia-reperfusion injury. Circ Res 83: 85-94.