Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine

European Journal of Neuroscience

Volumn 9, Issue 10, 1997, Pages 2077-2085

  Tanda, Gianluigi ^a   Di Chiara, G ^a,a   Frau, R ^a  

^a Department of Toxicology ^*

Author keywords

GBR 12909; Microdialysis; Nucleus accumbens; Psychostimulants; Self administration

Indexed keywords

AMPHETAMINE; CARRIER PROTEIN; COCAINE; DESIPRAMINE; DOPAMINE; DOPAMINE TRANSPORTER; NORADRENALIN; PSYCHOSTIMULANT AGENT; VANOXERINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIALYSIS; DOPAMINE BRAIN LEVEL; DOPAMINERGIC TRANSMISSION; DRUG EFFECT; EXTRACELLULAR FLUID; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; CARRIER PROTEINS; COCAINE; DESIPRAMINE; DEXTROAMPHETAMINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; KINETICS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MULTIVARIATE ANALYSIS; NERVE TISSUE PROTEINS; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PIPERAZINES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; SYMPORTERS;

EID: 0030666362     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01375.x     Document Type: Article

References (4)

1. Andersen, P. H. (1989) The dopamine uptake inhibitor GBR 12909: selectivity and molecular mechanism of action. Enr. J. I'harmacol., 166, 493-504.
2. Bassareo, V., Tanda, G., Pctromilli, P., Giua, C. and Di Chiara, G. (1996) Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex. Psychopharmacology, J2-4, 293-299.
3. Carboni, E., Tanda, G., Frau, R. and Di Chiara, G. (1990) Blockade of the noradrcnaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals. J. Neurochem., 55, 1067-1070.
4. Cass, W. A. and Gerhardt, G. A. (1995) In vivo assessment of dopamine uptake in rat medial prefrontal cortex: comparison with dorsal striatum and nucleus accumbens. J. Neurochem., 65, 201-207.