The aspirin metabolite sodium salicylate causes focal cerebral hemorrhage and cell death in rats with kainic acid-induced seizures

Neuroscience

Volumn 99, Issue 1, 2000, Pages 107-117

  Najbauer, J ^a,b   Schuman, E M ^a   Mamelak, A N ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aspirin; Cell death; Epilepsy; Hippocampus; Kainic acid; Neurotoxicity

Indexed keywords

ACETYLSALICYLIC ACID; DIAZEPAM; DNA FRAGMENT; DRUG METABOLITE; KAINIC ACID; SALICYLATE SODIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; CONTROLLED STUDY; EPILEPTIC STATE; HIPPOCAMPUS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; SEIZURE; TEMPORAL LOBE EPILEPSY; THALAMUS NUCLEUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CELL DEATH; CEREBRAL HEMORRHAGE; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MALE; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SODIUM SALICYLATE;

EID: 0034718198     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00158-5     Document Type: Article

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