Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase

Journal of Cell Biology

Volumn 148, Issue 4, 2000, Pages 811-824

  Fitzgerald, Marilyn L ^a   Wang, Zihua ^a   Park, Pyong Woo ^a   Murphy, Gillian ^b   Bernfield, Merton ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Cellular stress; Heparan sulfate; Mitogen activated protein kinase; Protein tyrosine kinase; Proteoglycan

Indexed keywords

GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN KINASE C; SYNDECAN; THROMBIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELL MEMBRANE; ENZYME ACTIVATION; HUMANS; HYDROXAMIC ACIDS; KINETICS; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; METALLOENDOPEPTIDASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; OSMOLAR CONCENTRATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; PROTEOGLYCANS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; SYNDECAN-1; SYNDECAN-4; SYNDECANS; TETRADECANOYLPHORBOL ACETATE; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

EID: 0034695918     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.148.4.811     Document Type: Article

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