-
1
-
-
0033305213
-
Peroxisome proliferator-activity receptors: Nuclear control of metabolism
-
Desvergne B., Wahli W. Peroxisome proliferator-activity receptors. nuclear control of metabolism Endocrinol Rev. 20:1999;649-688.
-
(1999)
Endocrinol Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
2
-
-
0032588487
-
PPARγ, the ultimate thrifty gene
-
Auwerx J. PPARγ, the ultimate thrifty gene. Diabetologia. 42:1999;1033-1049.
-
(1999)
Diabetologia
, vol.42
, pp. 1033-1049
-
-
Auwerx, J.1
-
3
-
-
0033542873
-
Medical significance of peroxisome proliferator-activated receptors
-
Vamecq J., Latruffe N. Medical significance of peroxisome proliferator-activated receptors. Lancet. 354:1999;141-148.
-
(1999)
Lancet
, vol.354
, pp. 141-148
-
-
Vamecq, J.1
Latruffe, N.2
-
4
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor γ
-
Nolte R.T., Wisely G.B., Westin S.et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor γ Nature. 395:1998;137-143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
-
5
-
-
0030297919
-
Adipogenesis and obesity: Rounding out the big picture
-
Spiegelman B.M., Flier J.S. Adipogenesis and obesity. rounding out the big picture Cell. 87:1996;377-389.
-
(1996)
Cell
, vol.87
, pp. 377-389
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
7
-
-
0032189782
-
Obesity associated with mutation in a genetic regulator of adipocyte differentation
-
Ristow M., Muller-Wieland D., Pfeiffer A., Krone W., Kahn C.R. Obesity associated with mutation in a genetic regulator of adipocyte differentation. N Engl J Med. 339:1998;953-959.
-
(1998)
N Engl J Med
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Muller-Wieland, D.2
Pfeiffer, A.3
Krone, W.4
Kahn, C.R.5
-
8
-
-
0031595923
-
A Pro 12 Ala substitution in the human peroxisome proliferator-activated receptor gamma2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index
-
Deeb S., Fajas L., Nemoto M., Laakso M., Fujimoto W., Auwerx J. A Pro 12 Ala substitution in the human peroxisome proliferator-activated receptor gamma2 is associated with decreased receptor activity, improved insulin sensitivity, and lowered body mass index. Nat Genet. 20:1998;284-287.
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.1
Fajas, L.2
Nemoto, M.3
Laakso, M.4
Fujimoto, W.5
Auwerx, J.6
-
9
-
-
0033213637
-
Rgamma is recruited for placental, cardiac, and adipose tissue development
-
Barak Y., Nelson M.C., Ong E.S., et al P.P.A. Rgamma is recruited for placental, cardiac, and adipose tissue development. Mol Cell. 4:1999;585-595.
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Et Al, P.P.A.4
-
10
-
-
0033212964
-
Rgamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota N., Terauchi Y., Miki H., et al P.P.A. Rgamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell. 4:1999;597-609.
-
(1999)
Mol Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Et Al, P.P.A.4
-
11
-
-
0033213631
-
Rgamma is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen E.D., Sarraf P., Troy A.E., et al P.P.A. Rgamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell. 4:1999;611-617.
-
(1999)
Mol Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Et Al, P.P.A.4
-
12
-
-
0032532152
-
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: A model for congenital generalized lipodystrophy
-
Shimomura I., Hammer R.E., Richardson J.A.et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue. a model for congenital generalized lipodystrophy Genes Dev. 12:1998;3182-3194.
-
(1998)
Genes Dev
, vol.12
, pp. 3182-3194
-
-
Shimomura, I.1
Hammer, R.E.2
Richardson, J.A.3
-
13
-
-
0032532753
-
Life without fat: A transgenic mouse
-
Moitra J., Mason M.M., Olive M.et al. Life without fat. a transgenic mouse Genes Devel. 12:1998;3168-3181.
-
(1998)
Genes Devel
, vol.12
, pp. 3168-3181
-
-
Moitra, J.1
Mason, M.M.2
Olive, M.3
-
14
-
-
0030658022
-
Coordinate regulation of the expression of the fatty acid transport protein (FATP) and acyl CoA synthetase genes by PPARα and PPARγ activators
-
Martin G., Schoonjans K., Lefebvre A., Staels B., Auwerx J. Coordinate regulation of the expression of the fatty acid transport protein (FATP) and acyl CoA synthetase genes by PPARα and PPARγ activators. J Biol Chem. 272:1997;28210-28217.
-
(1997)
J Biol Chem
, vol.272
, pp. 28210-28217
-
-
Martin, G.1
Schoonjans, K.2
Lefebvre, A.3
Staels, B.4
Auwerx, J.5
-
15
-
-
0030811602
-
The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue availability in the rat
-
Oakes N.D., Camilleri S., Furler S.M., Chisholm D.J., Kraegen E.W. The insulin sensitizer, BRL 49653, reduces systemic fatty acid supply and utilization and tissue availability in the rat. Metabolism. 46:1997;935-942.
-
(1997)
Metabolism
, vol.46
, pp. 935-942
-
-
Oakes, N.D.1
Camilleri, S.2
Furler, S.M.3
Chisholm, D.J.4
Kraegen, E.W.5
-
16
-
-
0032568310
-
Effect of troglitazone in insulin-treated patients with type II diabetes
-
Schwartz S., Raskin P., Fonseca V., Graveline J.F. Effect of troglitazone in insulin-treated patients with type II diabetes. N Engl J Med. 338:1998;861-866.
-
(1998)
N Engl J Med
, vol.338
, pp. 861-866
-
-
Schwartz, S.1
Raskin, P.2
Fonseca, V.3
Graveline, J.F.4
-
17
-
-
0026517631
-
Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects
-
Suter S.L., Nolan J.J., Wallace P., Gumbiner B., Olefsky J.M. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care. 15:1992;193-203.
-
(1992)
Diabetes Care
, vol.15
, pp. 193-203
-
-
Suter, S.L.1
Nolan, J.J.2
Wallace, P.3
Gumbiner, B.4
Olefsky, J.M.5
-
18
-
-
0032568257
-
Efficacy and metabolic effects of metformin and troglitazone in type II diabetes
-
Inzucchi S.E., Maggs D.G., Spollett G.R.et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes. N Engl J Med. 338:1998;867-872.
-
(1998)
N Engl J Med
, vol.338
, pp. 867-872
-
-
Inzucchi, S.E.1
Maggs, D.G.2
Spollett, G.R.3
-
19
-
-
0033022510
-
Troglitazone: A review of its use in the management of type 2 diabetes mellitus
-
Plosker G.L., Faulds D. Troglitazone: a review of its use in the management of type 2 diabetes mellitus. Drugs. 57:1999;409-438.
-
(1999)
Drugs
, vol.57
, pp. 409-438
-
-
Plosker, G.L.1
Faulds, D.2
-
20
-
-
0033044593
-
Rosiglitazone
-
discussion 931-32
-
Balfour J.A., Plosker G.L. Rosiglitazone. Drugs. 57:1999;921-930. discussion 931-32.
-
(1999)
Drugs
, vol.57
, pp. 921-930
-
-
Balfour, J.A.1
Plosker, G.L.2
-
21
-
-
0032568261
-
Hepatic dysfunction associated wtih troglitazone
-
Watkins P.B., Whitcomb R.W. Hepatic dysfunction associated wtih troglitazone. N Engl J Med. 338:1998;916-917.
-
(1998)
N Engl J Med
, vol.338
, pp. 916-917
-
-
Watkins, P.B.1
Whitcomb, R.W.2
-
22
-
-
0031738012
-
An autopsy case of troglitazone-induced fulminant hepatitis
-
Shibuya A., Watanabe M., Fujita Y.et al. An autopsy case of troglitazone-induced fulminant hepatitis. Diabetes Care. 21:1998;2140-2143.
-
(1998)
Diabetes Care
, vol.21
, pp. 2140-2143
-
-
Shibuya, A.1
Watanabe, M.2
Fujita, Y.3
-
24
-
-
0033972218
-
Hepatocellular injury in a patient receiving rosiglitazone: A case report
-
Al-Salman J., Arjomand H., Kemp D.G., Mittal M. Hepatocellular injury in a patient receiving rosiglitazone: a case report. Ann Intern Med. 132:2000;121-124.
-
(2000)
Ann Intern Med
, vol.132
, pp. 121-124
-
-
Al-Salman, J.1
Arjomand, H.2
Kemp, D.G.3
Mittal, M.4
-
26
-
-
0031667938
-
Activators of the nuclear receptor PPARγ enhance colon polyp formation
-
Saez E., Tontonoz P., Nelson M.C.et al. Activators of the nuclear receptor PPARγ enhance colon polyp formation. Nat Med. 4:1998;1058-1061.
-
(1998)
Nat Med
, vol.4
, pp. 1058-1061
-
-
Saez, E.1
Tontonoz, P.2
Nelson, M.C.3
-
27
-
-
0031793850
-
Novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor α and γ: Effect of PPARα activation on normal lipid metabolism in liver of Zucker fatty rats
-
Murakami K., Tobe K., Ide T., et al A. novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor α and γ effect of PPARα activation on normal lipid metabolism in liver of Zucker fatty rats Diabetes. 47:1998;1841-1847.
-
(1998)
Diabetes
, vol.47
, pp. 1841-1847
-
-
Murakami, K.1
Tobe, K.2
Ide, T.3
Et Al, A.4
-
28
-
-
0032898052
-
Pharmacological profiles of a novel oral antidiabetic agent, JTT-501, an isoxazolidinedione derivative
-
Shibata T., Matsui K., Nagao K., Shinkai H., Yonemori F., Wakitani K. Pharmacological profiles of a novel oral antidiabetic agent, JTT-501, an isoxazolidinedione derivative. Eur J Pharmacol. 364:1999;211-219.
-
(1999)
Eur J Pharmacol
, vol.364
, pp. 211-219
-
-
Shibata, T.1
Matsui, K.2
Nagao, K.3
Shinkai, H.4
Yonemori, F.5
Wakitani, K.6
-
29
-
-
0032897935
-
BM 17.0744: A structurally new antidiabetic compound with insulin-sensitizing and lipid-lowering activity
-
Pill J., Kuhnle H.F. BM 17.0744: a structurally new antidiabetic compound with insulin-sensitizing and lipid-lowering activity. Metabolism. 48:1999;34-40.
-
(1999)
Metabolism
, vol.48
, pp. 34-40
-
-
Pill, J.1
Kuhnle, H.F.2
-
30
-
-
0030062325
-
The structure activity relationship between peroxisome proliferator activated receptor γ antagonism and the antihyperglycemic activity of thiazolidinediones
-
Willson T.M., Cobb J.E., Cowan D.J.et al. The structure activity relationship between peroxisome proliferator activated receptor γ antagonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem. 39:1996;665-668.
-
(1996)
J Med Chem
, vol.39
, pp. 665-668
-
-
Willson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
-
31
-
-
0029745382
-
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ: Binding and activation correlate with antidiabetic actions in db/DB mice
-
Berger J., Bailey P., Biswas C.et al. Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ binding and activation correlate with antidiabetic actions in db/DB mice Endocrinology. 137:1996;4189-4195.
-
(1996)
Endocrinology
, vol.137
, pp. 4189-4195
-
-
Berger, J.1
Bailey, P.2
Biswas, C.3
-
32
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura K.D., Tissenbaum H.A., Liu Y., Ruvkun G. Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science. 277:1997;942-946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
33
-
-
0033603208
-
Autonomous control of cell and organ size by CHICO, a drosophila homolog of vertebrate IRS1-4
-
Bohni R., Riesgo-Escovar J., Oldham S.et al. Autonomous control of cell and organ size by CHICO, a drosophila homolog of vertebrate IRS1-4. Cell. 97:1999;865-875.
-
(1999)
Cell
, vol.97
, pp. 865-875
-
-
Bohni, R.1
Riesgo-Escovar, J.2
Oldham, S.3
-
34
-
-
0033610079
-
Gene expression profile of aging and its retardation by caloric restriction
-
Lee C.K., Klopp R.G., Weindruch R., Prolla T.A. Gene expression profile of aging and its retardation by caloric restriction. Science. 285:1999;1390-1393.
-
(1999)
Science
, vol.285
, pp. 1390-1393
-
-
Lee, C.K.1
Klopp, R.G.2
Weindruch, R.3
Prolla, T.A.4
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