12-Helix formation in aqueous solution with short β-peptides containing pyrrolidine-based residues

Journal of the American Chemical Society

Volumn 122, Issue 19, 2000, Pages 4821-4822

  Wang, Xifang ^a   Espinosa, Juan F ^a   Gellman, Samuel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTANE DERIVATIVE; OLIGOMER; PYRROLIDINE DERIVATIVE; SYNTHETIC PEPTIDE;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; OLIGOMERIZATION; PEPTIDE ANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0034679022     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja000093k     Document Type: Article

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41. This work was supported by the National Institutes of Health (GM56414) and by the Leukemia Society of America. J.F.E. was supported by a fellowship from the Ministerio de Educacion y Cultura (Spain) and the Fulbright Comission. NMR measurements were made in the Department of Chemistry (NIH 1 S10 RR04981) and at the National Magnetic Resonance Facility at Madison (NIH RR02301, RR02781, and RR08438; NSF DMB-8415048 and BIR-9214394; U.S. Department of Agriculture). CD measurements were made in the Biophysics Instrumentation Facility (NSF BIR-9512577). We thank G. W. Fleet and W. F. DeGrado for sharing results prior to publication.