Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes

Journal of Experimental Medicine

Volumn 191, Issue 2, 2000, Pages 239-252

  Lucchiari Hartz, Maria ^a   Van Endert, Peter M ^b   Lauvau, Grégoire ^b   Maier, Reinhard ^c   Meyerhans, Andreas ^c   Mann, Derek ^d   Eichmann, Klaus ^a   Niedermann, Gabriele ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c SAARLAND UNIVERSITY   (Germany)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Antigen processing; Cytotoxic T lymphocyte epitopes; HW Nef; Naturally processed peptides; Proteasome

Indexed keywords

AMINOPEPTIDASE; EPITOPE; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME;

AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOTOXIC T LYMPHOCYTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION;

ACETYLCYSTEINE; ANTIGEN PRESENTATION; ATP-BINDING CASSETTE TRANSPORTERS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; EPITOPES, T-LYMPHOCYTE; GENE PRODUCTS, NEF; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV-1; HLA-A2 ANTIGEN; HLA-B7 ANTIGEN; HUMANS; LIGANDS; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; RESEARCH DESIGN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0034677151     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.2.239     Document Type: Article

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