The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells

European Journal of Immunology

Volumn 27, Issue 1, 1997, Pages 336-341

  Cerundolo, Vincenzo ^a   Benham, Adam ^b   Braud, Veronique ^a   Mukherjee, Siddhartha ^a   Gould, Keith ^c   Macino, Beatrice ^d   Neefjes, Jacques ^b   Townsend, Alain ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c ST MARY S HOSPITAL   (United Kingdom)

^d UNIVERSITY OF PADOVA   (Italy)

Author keywords

Antigen presentation; Cytotoxic T lymphocyte; Lactacystin; Major histocompatibility complex class I molecule; Proteasome

Indexed keywords

ENZYME INHIBITOR; EPITOPE; LACTACYSTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, VIRAL; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOSOL; EPITOPES; H-2 ANTIGENS; HUMANS; LEUPEPTINS; MICE; MULTIENZYME COMPLEXES; NUCLEOCAPSID PROTEINS; NUCLEOPROTEINS; ORTHOMYXOVIRIDAE; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; VACCINIA VIRUS; VIRAL CORE PROTEINS;

EID: 0031032422     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270148     Document Type: Article

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