The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER

Immunity

Volumn 4, Issue 2, 1996, Pages 159-165

  Powis, Simon J ^b   Young, Lesley L ^e   Joly, Etienne ^e   Barker, Patrick J ^a   Richardson, Louise ^e   Brandt, Remco P ^c   Melief, Cornelis J ^c   Howard, Jonathan C ^d   Butcher, Geoffrey W ^e  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF COLOGNE   (Germany)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SYNTHETIC PEPTIDE;

ALLELE; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; ENDOPLASMIC RETICULUM; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS;

EID: 0029930418     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80680-9     Document Type: Article

References (38)

1. Butcher, G.W. (1987). A list of monoclonal antibodies specific for alloantigens of the rat. J. Immunogenet. 14, 163-176.
2. Deverson. E.V., Gow, I.R., Coadwell, W.J., Monaco, J.J., Butcher, G.W., and Howard, J.C. (1990). MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature 348, 738-741.
3. Eisenlohr, L.C., Bacik, I., Bennink, J.R., Bernstein, K., and Yewdell, J.W. (1992). Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes. Cell 71, 963-972.
4. Elliott, T., Willis, A., Cerundolo, V., and Townsend, A. (1995). Processing of major histocompatibility class-I restricted antigens in the endoplasmic reticulum. J. Exp. Med. 181, 1481-1491.
5. Falk, K., Rötzschke, O., Stevanovic, S., Jung, G., and Rammensee, H.-G. (1991). Allele specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351, 290-296.
6. Feltkamp, M.C.W., Smits, H.L., Vierboom, M.P.M., Minaar, R.P., de Jongh, B.M., Drijfhout, J.W., ter Schegget, J., Melief, C.J.M., and Kast, W.M. (1993). Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16 transformed cells. Eur. J. Immunol. 23, 2242-2247
7. + T cells. Nature 364, 158-161
8. Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
9. Heemels, M.-T., and Ploegh, H.L. (1994). Substrate specificity of allelic variants of the TAP peptide transporter. Immunity 1, 775-784.
10. Heemels, M.-T., Schumacher, T.N.M., Wonigeit, K., and Ploegh, H.L. (1993). Peptide translocation by variants of the transporter associated with antigen processing. Science 262, 2059-2063.
11. Hombach, J., Pircher, H., Tonegawa, S., and Zinkernagel, R.M. (1995). Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein. J. Exp. Med. 182, 1615-1619.
12. Hunt, D.F., Henderson, R.A., Shabanowitz, J., Sakaguchi, K., Michel, H., Sevilir, N., Cox, A.L., Apella, E., and Engelhard, V.H. (1992). Characterization of peptides bound to the MHC class I molecule HLA-A2.1 by mass spectrometry. Science 255, 1261-1263.
13. Jardetzky, T.S., Lane, W.S., Robinson, R.A., Madden, D.R., and Wiley, D.C. (1991). Identification of self peptides bound to purified HLA-B27. Nature 353, 326-329.
14. Joly, E., and Oldstone, M.B.A. (1992). Neuronal cells are deficient in loading peptides onto M HC class I molecules. Neuron 8, 1185-1190.
15. Joly, E., Deverson, E.V., Coadwell, W.J., Günther, E., Howard, J.C., and Butcher, G.W. (1994). The distribution of Tap 2 alleles among laboratory rat RT1 haplotypes. Immunogenetics 40, 45-53.
16. u MHC class I heavy chain by a novel PCR based method. Immunogenetics 41, 326-328.
17. Livingstone, A.M., Powis, S.J., Diamond, A.G., Butcher, G.W., and Howard, J.C. (1989). A trans-acting major histocompatibility complex-linked gene whose alleles determine gain and loss changes in the antigenic structure of a classical class I molecule. J. Exp. Med. 170, 777-795.
18. Livingstone, A.M., Powis, S.J., Gunther, E., Cramer, D.V., Howard, J.C., and Butcher, G.W. (1991). Cim: an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes. Immunogenetics 34, 157-163.
19. Ljunggren, H.-G., Stam, N., Öhlén, C., Neefjes, J.J., Höglund, P., Heemels, M.-T., Bastin, J., Schumacher, T.N.M., Townsend, A., Kärre, K., and Ploegh, H.L. (1990). Empty MHC class I molecules come out in the cold. Nature 346, 476-480.
20. Momburg, F., Roelse, J., Howard, J.C., Butcher, G.W., Hämmerling, G.J., and Neefjes, J.J. (1994). Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature 367, 648-651.
21. Monaco, J. J., Cho, S., and Attaya, M. (1990). Transport protein genes in the murine MHC: possible implications for antigen processing. Science 250, 1723-1726.
22. Neefjes, J.J., Momburg, F., and Hämmerling, G.J. (1993). Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 261, 769-771.
23. Powis, S.J., Townsend, A.R.M., Deverson, E.V., Bastin, J., Butcher, G.W., and Howard, J.C. (1991a). Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature 354, 528-531.
24. Powis, S.J., Howard, J.C., and Butcher, G.W. (1991b). The major histocompatibility complex class II-linked cim locus controls the kinetics of intracellular transport of a classical class I molecule. J. Exp. Med. 173, 913-921.
25. Powis, S.J., Deverson, E.V., Coadwell, W.J., Ciruela, A., Huskisson, N.S., Smith, H., Butcher, G.W., and Howard, J.C. (1992). Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature 357, 211-215.
26. Powis, S.J., Young, L.L., Barker, P.J., Richardson, L., Howard, J.C., and Butcher, G.W. (1993). MHC-encoded ABC transporters and rat class I peptide motifs. Trans. Proc. 25, 2752-2754.
27. Rada, C., Lorenzi, R., Powis, S., van den Bogaerde, J., Parham, P., and Howard, J. (1989). Concerted evolution of class I genes in the major histocompatibility complex of murine rodents. Proc. Natl. Acad. Sci. USA 87, 2167-2171.
28. Rötzschke, O., Falk, K., Stevanovic, S., Gnau, V., Jung, G., and Rammensee, H.-G. (1994). Dominant aromatic/aliphatic C-terminal anchor in HLA-B*2702 and B*2705 peptide motifs. Immunogenetics 39, 74-77.
29. Schumacher, T.N.M., Heemels, M.-T., Neefjes, J.J., Kast, W.M., Melief, C.J.M., and Ploegh, H.L (1990). Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell 62, 563-567.
30. Shepherd, J.C., Schumacher, T.N.M., Ashton-Rickardt, P.G., Imaeda, S., Ploegh, H.L., Janeway, C.A., and Tonegawa, S. (1993). TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell 74, 577-584.
31. Spies, T., Bresnahan, M., Bahram, S., Arnold, D., Blanck, G., Mellins, E., Pious, D., and DeMars, R. (1990). A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature 348, 744-747.
32. a suggests an allele-specific motif. Immunogenetics 41, 329-331.
33. Townsend, A., Öhlén, C., Bastin, J., Ljunggren, H.-G., Foster, L., and Kärre, K. (1989). Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 340, 443-448.
34. Trowsdale, J., Hanson. I., Mockridge, I., Beck, S., Townsend, A., and Kelly, A. (1990). Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature 348, 741-744.
35. b molecule. Nature 348, 213-216.
36. Williams, R.M., Singer, D.E., Rodday, P., and Bennet, M. (1980). Hybrid resistance to BN myelogenous leukemia parallels resistance to transplantation of normal BN bone marrow. Leukocyte Res. 4, 261-266
37. Yang, Y., Früh, K., Chambers, J., Waters, J.B., Wu, L., Spies, T., and Peterson, P. (1992). Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules. J. Biol. Chem. 267, 11669-11672.
38. Yokosawa, H., and Ishii, S.-I. (1979). Immobilized anhydrotrypsin as a biospecific affinity adsorbent for the peptides produced bytrypsin like proteases. Anal. Biochem. 98, 198-203.