Identification of pairwise interactions in the α-neurotoxin-nicotinic acetylcholine receptor complex through double mutant cycles

Journal of Biological Chemistry

Volumn 273, Issue 18, 1998, Pages 10958-10964

  Ackermann, Elizabeth J ^a   Ang, Eudora T H ^a   Kanter, Joan R ^a   Tsigelny, Igor ^a   Taylor, Palmer ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTOXIN; NICOTINIC RECEPTOR;

ARTICLE; BINDING SITE; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; COBRA NEUROTOXINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RECEPTORS, NICOTINIC; SEQUENCE HOMOLOGY, AMINO ACID; THERMODYNAMICS;

NAJA; NAJA MOSSAMBICA MOSSAMBICA;

EID: 0032079868     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.18.10958     Document Type: Article

References (55)

1. Unwin, N. (1993) Cell 72, 31-41
2. Galzi, J.-L., and Changeux, J.-P. (1994) Curr. Opin. Struct. Biol. 4, 554-565
3. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
4. Hucho, F., Tsetlin, V. I., and Machold, J. (1996) Eur. J. Biochem. 239, 539-557
5. Blount, P., and Merlie, J. P. (1989) Neuron 3, 349-357
6. Sine, S. M., and Claudio, T. (1991) J. Biol. Chem. 266, 19369-19377
7. Kao, P. N., Dwork, A. J., Kaldany, R. J., Silver, M. L., Wideman, J., Stein, S., and Karlin, A. (1984) J. Biol. Chem. 259, 11662-11665
8. Dennis, M., Giraudat, J., Kotzyba-Hibert, F., Goeldner, M., Hirth, C., Chang, J.-Y., Lazure, C., Chretien, M., and Changeux, J.-P. (1988) Biochemistry 27, 2346-2357
9. Abramson, S. N., Li, Y., Culver, P., and Taylor, P. (1989) J. Biol. Chem. 264, 12666-12672
10. Galzi, J.-L., Revah, F., Black, D., Goeldner, M., Hirth, C., and Changeux, J.-P. (1990) J. Biol. Chem. 265, 10430-10437
11. Middleton, R. E., and Cohen, J. B. (1991) Biochemistry 30, 6987-6997
12. Czajkowski, C., and Karlin, A. (1995) J. Biol. Chem. 270, 3160-3164
13. Tomaselli, G. F., McLaughlin, J. T., Jurman, M. E., Hawrot, E., and Yellen, G. (1991) Biophys. J. 60, 721-727
14. O'Leary, M. E., and White, M. M. (1992) J. Biol. Chem. 267, 8360-8365
15. Sine, S. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9436-9440
16. Aylwin, M. L., and White, M. M. (1994) Mol. Pharmacol. 46, 1149-1155
17. Aylwin, M. L., and White, M. M. (1994) FEBS Lett. 349, 99-103
18. Fu, D.-X., and Sine, S. M. (1994) J. Biol. Chem. 269, 26152-26157
19. O'Leary, M. E., Filatov, G. N., and White, M. M. (1994) Am. J. Physiol. 266, C648-C653
20. Sine, S. M., Quiram, P., Papanikolaou, F., Kreienkamp, H.-J., and Taylor, P. (1994) J. Biol. Chem. 269, 8808-8816
21. Nowak, M. W., Kearney, P. C., Sampson, J. R., Saks, M. E., Labarca, C. G., Silverman, S. K., Zhong, W., Thorson, J., Abelson, J. N., Davidson, N., Schultz, P. G., Dougherty, D. A., and Lester, H. A. (1995) Science 268, 439-442
22. Sine, S. M., Kreienkamp, H.-J., Bren, N., Maeda, R., and Taylor, P. (1995) Neuron 15, 205-211
23. Sugiyama, N., Boyd, A. E., and Taylor, P. (1996) J. Biol. Chem. 271, 26575-26581
24. Unwin, N. (1993) J. Mol. Biol. 229, 1101-1124
25. Unwin, N. (1996) J. Mol. Biol. 257, 586-596
26. Tgigelny, I., Sugiyama, N., Sine, S. M., and Taylor, P. (1997) Biophys. J. 73, 52-66
27. Kreienkamp, H.-J., Sine, S. M., Maeda, R. K., and Taylor, P. (1994) J. Biol. Chem. 269, 8108-8114
28. Endo, T., and Tamiya, N. (1987) Pharmacol. Ther. 34, 403-451
29. Menez, A. (1991) in Snake Toxins (Harvey, A. L., ed) pp. 35-90, Pergamon Press, New York
30. Basus, V. J., Billetet, M., Love, R. A., Stroud, R. M., and Kuntz, I. D. (1988) Biochemistry 27, 2763-2771
31. Hatanaka, H., Oka, M., Kohda, D., Tate, S.-I., Suda, A., Tamiya, N., and Inagaki, F. (1994) J. Mol. Biol. 240, 155-166
32. Peng, S.-S., Kumar, T. K. S., Jayaraman, G., Chang, C.-C., and Yu, C. (1997) J. Biol. Chem. 272, 7817-7823
33. Low, B. W., Preston, H. S., Sato, A., Rosen, L. S., Searl, J. E., Rudko, A. D., and Richardson, J. S. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 2991-2994
34. Agard, D. A., and Stroud, R. M. (1982) Acta Crystallogr. A 38, 186-194
35. Arnoux, B., Menez, R., Drevet, P., Boulain, J.-C., Ducruix, A., and Menez, A. (1994) FEBS Lett. 342, 12-14
36. Ackermann, E. J., and Taylor, P (1997) Biochemistry 36, 12836-12844
37. Ranganathan, R., Lewis, J. H., and MacKinnon, R. (1996) Neuron 16, 131-139
38. Naranjo, D., and Miller, C. (1996) Neuron 16, 123-130
39. Hidalgo, P., and MacKinnon, R. (1995) Science 268, 307-310
40. Sugiyama, N., Marchot, P., Kawanishi, C., Osaka, H., Molles, B., Sine, S. M., and Taylor, P. (1998) Mol. Pharmacol., in press
41. Sine, S., and Taylor, P. (1979) J. Biol. Chem. 254, 3315-3325
42. Pillet, L., Tremeau, O., Ducancel, F., Drevet, P., Zinn Justin, S., Pinkasfeld, S., Boulain, J.-C., and Menez, A. (1993) J. Biol. Chem. 268, 909-916
43. Tremeau, O., Lemaire, C., Drevet, P., Pinkasfeld, S., Ducancel, F., Boulain, J.-C., and Menez, A. (1995) J. Biol. Chem. 270, 9362-9369
44. Ducancel, F., Merienne, K., Fromen-Romano, C., Tremeau, O., Pillet, L., Drevet, P., Zinn-Justin, S., Boulain, J.-C., and Menez, A. (1996) J. Biol. Chem. 271, 31345-31353
45. Carter, P. J., Winter, G., Wilkinson, A. J., and Fersht, A. R. (1984) Cell 38, 835-840
46. Schreiber, G., and Fersht, A. R. (1995) J. Mol. Biol. 248, 478-486
47. Wells, J. (1990) Biochemistry 29, 8509-8517
48. Horovitz, A., and Fersht, A. R. (1990) J. Mol. Biol. 214, 613-617
49. LiCata, V. J., and Akers, G. K. (1995) Biochemistry 34, 3133-3139
50. Faiman, G. A., and Horovitz, A. (1996) Protein Eng. 9, 315-316
51. McLane, K. E., Wu, X., Diethelm, B., and Conti-Tronconi, B. M. (1991) Biochemistry 30, 4925-4934
52. Basus, V. J., Song, G., and Hawrot, E. (1993) Biochemistry 32, 12290-12298
53. Chaturvedi, V., Donnelly-Roberts, D. L., and Lentz, T. L. (1993) Biochemistry 32, 9570-9576
54. Fulachier, M.-H., Mourier, G., Cotton, J., Servent, D., and Menez, A. (1994) FEBS Lett. 338, 331-338
55. Barchan, D., Ovadia, M., Kochva, E., and Fuchs, S. (1995) Biochemistry 34, 9172-9176