Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera

Developmental Biology

Volumn 224, Issue 2, 2000, Pages 152-167

  Wang, Cheng Chun ^a   Biben, Christine ^a   Robb, Lorraine ^c   Nassir, Fatiha ^d   Barnett, Louise ^c   Davidson, Nicholas O ^d   Koentgen, Frank ^c   Tarlinton, David ^c   Harvey, Richard P ^a,b  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Homeobox; Lamina propria; Leukocyte homing; Lymphocyte homing; MAdCAM 1; NK 2; Nkx2 3; Peyer's patches; Spleen

Indexed keywords

CELL ADHESION MOLECULE; DNA; HOMEODOMAIN PROTEIN; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; EMBRYO; ENDOTHELIUM CELL; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; HOMEOBOX; IMMUNOHISTOCHEMISTRY; LAMINA PROPRIA; LYMPHOCYTE HOMING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEYER PATCH; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN;

ANIMALIA; MAMMALIA;

EID: 0034663328     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9749     Document Type: Article

References (64)

1. Differential requirements for α4 integrins during fetal and adult hematopoiesis
2. Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
3. The gene tinman is required for specification of the heart and visceral muscles in Drosophila
4. Heart development in Drosophila and its relationship to vertebrates
5. Regional specialization in the mucosal immune system: Primed cells do not always home along the same track
6. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue
7. Chick NKx-2.3 represents a novel family member of vertebrate homologues to Drosophila homeobox gene tinman: Differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development
8. Lymphocyte homing and homeostasis
9. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
10. Cytokine regulation of secondary lymphoid organ development
11. Overex-pression of the tinman-related genes XNkx-2.5 and XNkx-2.3 in Xenopus embryos results in myocardial hyperplasia
12. Lymphotoxin α3 induces chemokines and adhesion molecules: Insight into the role of LTα in inflammation and lymphoid organ development
13. The Hox11 gene is essential for cell survival during spleen development
14. Expression of lymphocyte homing receptors and vascular addressins in low grade gastric B-cell lymphomas of mucosa-associated lymphoid tissue
15. Preferential dissemination of B-cell gastric mucosa-associated lymphoid tissue (MALT) lymphoma to splenic marginal zone
16. A putative chemokine receptor BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartment of the spleen
17. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
18. The zinc finger proteins pannier and GATA4 function as cardiogenic factors in Drosophila
19. Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
20. Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes
21. Mucosal addressin is required for the development of diabetes in nonobese mice
22. NK-2 homeobox genes and heart development
23. Follicular dendritic cell (FDC) precursors in primary lymphoid tissues
24. Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches
25. Distinct roles for lymphotoxin-α and tumour necrosis factor in organogenesis and spatial organisation of lymphoid tissue
26. Lymphocyte migration in the spleen: The effect of macrophage elimination
27. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen
28. Hox genes in vertebrate development
29. 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches
30. Homeobox genes: Their function in Drosophila segmentation and pattern formation
31. Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signalling
32. Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses
33. A new tinman-related gene, nxk2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm
34. MAdCAM-1 costimulates T cell proliferation exclusively through integrin alpha4betaT, whereas VCAM-1 and CS-1 peptide use alpha4betal: Evidence for 'remote' costimulation and induction of hyperresponsiveness to B7 molecules
35. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5
36. - cells to colonize lymph nodes
37. Transcription factors in cardiogenesis in the amphibian, Xenopus laevis
38. Macrophages in haemopoietic and other tissues of the developing mouse detected by the monoclonal antibody F4/80
39. Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin alpha4beta1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes
40. The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development
41. Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
42. Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes
43. + T cells
44. Using genetically engineered mice to understand apolipoprotein-B deficiency syndromes in humans
45. Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice
46. From insect eye to vertebrate muscle: Redeployment of a regulatory network
47. Hox 11 controls the genesis of the spleen
48. Generation of intestinal T cells from progenitors residing in gut cryptopatches
49. Organisation, regulatory sequences, and alternative spliced transcripts of the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) gene
50. Mucosal T lymphocyte numbers are selectively reduced in integrin α(E) (CD103)-deficient mice
51. A Cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
52. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-kappa B-inducing kinase
53. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
54. Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7
55. A tissue-specific endothelial cell molecule involved in lymphocyte homing
56. Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display
57. Induction of the gene encoding mucosal vascular addressin cell adhesion molecule 1 by tumour necrosis factor a is mediated by NF-κB proteins
58. Expression of the Nkx3.1 homeobox gene during pre and postnatal development
59. Bapx1: An evolutionarily conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton
60. The murine bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen
61. Critical role for β7 integrins in formation of the gut-associated lymphoid tissue
62. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
63. Interaction of monocytoid cells with the mucosal addressin MAdCAM-1 via the integrins VLA-4 and LPAM-1
64. - cells in the embryonic intestine induces the organising center of Peyer's patches