The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-dependent signaling pathways

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 25, 1996, Pages 14845-14850

  Carroll, Martin ^a   Tomasson, Michael H ^a   Barker, George F ^a   Golub, Todd R ^a,b   Gilliland, D Gary ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

AMINO TERMINAL SEQUENCE; CELL MIGRATION; CELL TRANSFORMATION; CHRONIC MYELOMONOCYTIC LEUKEMIA; CONFERENCE PAPER; ENZYME ACTIVITY; ERYTHROLEUKEMIA; GENE DELETION; GENE REARRANGEMENT; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY;

DNA-BINDING PROTEINS; HUMANS; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-ETS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

MURINAE;

EID: 0029966854     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.25.14845     Document Type: Article

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