-Amyloid induces increased release of interleukin-1β from lipopolysaccharide-activated human monocytes

Journal of Neuroimmunology

Volumn 67, Issue 1, 1996, Pages 21-29

  Lorton, Dianne ^a,b   Kocsis, June Marie ^a   King, Lynda ^c   Madden, Kelly ^c   Brunden, Kurt R ^a  

^a GUILFORD PHARMACEUTICALS INC   (United States)

^b SUN HEALTH RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Alzheimer's disease; Inflammation; Interleukin 1 ; Monocyte cell line; Amylase

Indexed keywords

AMYLOID BETA PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; INTERLEUKIN 1; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CELL LINE; HUMAN; INFLAMMATION; MICROGLIA; MONOCYTE; PRIORITY JOURNAL; DOSE RESPONSE; DRUG EFFECT; IMMUNOLOGY; METABOLISM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; HUMANS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MICROGLIA; MONOCYTES; PEPTIDE FRAGMENTS;

EID: 0030153520     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(96)00030-6     Document Type: Article

References (66)

1. Abraham, C.R., Selko, D.J. and Potter, H. (1988) Immunohistochemical identification of the serum protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52, 487-501.
2. Anderson, J.P., Esch, F.S., Keim, P.S., Sambamurti, I., Lieberburg, I. and Robakis, N.K. (1991) Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neurosci. Lett. 128, 126-128.
3. Araujo, D.M. and Cotman, C.W. (1992) β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease. Brain Res. 569, 141-145.
4. Barnum, S.R., Jones, J.L. and Benveniste, E.N. (1993) Interleukin-1 and tumor necrosis factor-mediated regulation of C3 gene expression in human astroglioma cells. Glia 7, 225-36.
5. Bauer, J., Strauss, S., Schreiter-Gasser, U., Ganter, U., Schlegel, P., Witt, I., Yolk, B. and Berger, M. (1991) Interleukin-6 and α2-macro-globulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett. 282, 127-131.
6. Baumann, H., Richards, C. and Gauldie, J. (1987) Interaction among hepatocyte-stimulting factors, interleukin 1 and glucocorticoid for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells. J. Immunol. 139, 4122-4128.
7. Castano, E.M. and Frangione, B. (1988) Biology of disease. Human amyloidosis, Alzheimer's disease and related disorders. Lab. Invest. 58, 122-132.
8. Chung, I.Y. and Benveniste, E.N. (1990) Tumor necrosis factor-α production by astrocytes: induction by lipopolysaccharide, interferon-γ and interleukin-1β. J. Immunol. 144, 2999.
9. Colton, C. and Gilbert, D. (1987) Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223, 284-288.
10. Colton, C.A., Yao, J., Taffs, R.E., Keri, J.E. and Oster-Granite, M.L. (1991) Abnormal production of interleukin-1 by microglia from trisomy 16 mice. Neurosci. Lett. 132, 270-274.
11. De Strooper, B. and Van Leuven, F. (1993) α2-macroglobulin and subacute-phase responses in Alzheimer's disease. Immunol. Today 14, 143-144.
12. Duffy, P.E., Rapport, M. and Graf, L. (1980) Glial fibrillary acidic protein and Alzheimer-type senile dementia. Neurology 30, 778-782.
13. Duong, T., Pommier, E.C. and Scheibel, A.B. (1989) Immunodetection of the amyloid P component in Alzheimer's disease. Acta Neuropathol. 78, 429-437.
14. Eikelenboom, P., Hack, C.E., Rozemuller, J.M. and Stam, F.C. (1989) Complement activation in amyloid plaques in Alzheimer's dementia. Virchows Arch. Cell. Pathol. 56, 259-262.
15. Esch, R.S., Ieim, P.S., Beattie, E.C., Blacher, R.W., Culwell, A.R., Otersdorf, T., McClure, D. and Ward, P.J. (1990) Cleavage of amyloid β peptide during constitutive processing of its precursor. Science 248, 1122-1124.
16. Fontana, A., Kristensen, F., Dubs, R., Gemsa, D. and Weber, E. (1982) Production of prostaglandin E and interleukin-1 like factor by cultured astrocytes and C6 glioma cells. J. Immunol. 129, 2413-2419.
17. Frederickson, R.C.A. (1991) Astroglia in Alzheimer's disease. Neurobiol. Aging 13, 239-253.
18. Frederickson, R.C.A. and Brunden, K.R. (1994) New opportunities in AD research - Roles of immunoinflammatory responses and glia. Alzheimer Disease Associated Disorders 8, 159-165.
19. Frei, K., Siepl, C., Groscurth, P., Bodmer, S. and Fontana, A. (1988) Immunobiol. Microglial Cells. Ann. NY Acad. Sci. 540, 218-227.
20. Gadient, R.A., Cron, K.C. and Otten, U. (1990) Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes. Neurosci. Lett. 117, 335-340.
21. Gitter, B.D., Cox, L.M., Keith, P.T., Rydel, R.E. and May, P.C. (1993) Amyloid Beta Peptide (Aβ) potentiates cytokine secretion by interleukin-1β activated human astrocytoma cells. Soc. Neurosci. Abstr. 19, 832.
22. Glenner, G.G. and Wong, C.W. (1984) Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890.
23. Goate, A., Chartier-Harlin, M.-C. and Mullan, M. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-707.
24. Goldgaber, D., Harris, H.W., Hla, T., Maciag, T., Donnelly, R.J., Jocobsen, J.S., Vitek, M.P. and Gadjusek, D.C. (1989) Interleukin-1 regulates synthesis of amyloid β-protein precursor mRNA in human endothelial cells. Proc. Nat. Acad. Sci. USA. 86, 7606-7610.
25. Golin, P.A., Kalaria, R.N., Eikelenboom, P., Rozemuller, A. and Perry, G. (1992) α1-antitrypsin and α1-antichymotrypsin are in the lesions of Alzheimer's Disease. Neurorep. 3, 201-203.
26. Griffin, W.S.T., Stanley, L.C., Ling, C., White, L., Macleod, V., Perrott, L.J., White III, C.L. and Araoz, C. (1989) Brain interleukin-1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer's disease. Proc. Nat. Acad. Sci. USA 86, 7611-7615.
27. + microglia are associated with the presence of dystrophic neurites in β-amyloid plaques in Alzheimer's disease. Soc. Neurosci. Abstr. 20, 606.
28. Guilian, D. and Lachman, L.B. (1985) Interleukin 1 stimulation of astroglial proliferation after brain injury. Science 228, 497-499.
29. Guilian, D. and Baker, T.J. (1986) Characterization of ameboid microglia isolated from the developing mammalian brain. J. Neuroscience 6, 2163-2178.
30. Guilian, D., Baker, T.J., Shih, L.N. and Lachman, L.B. (1986) Interleukin-1 of the central nervous system is produced by ameboid microgial. J. Exp. Med. 164, 549-604.
31. Guilian, D., Woodward, J., Young, D.G., Krebs, J.F. and Lachman, L.B. (1988) Interleukin-1 injection into mammalian brain stimulates astrogliosis and neovascularization. J. Neurosci. 8, 2485.
32. Haga, S., Akai, K. and Ishii, T. (1989) Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. Acta Neuropathol. 77, 569-575.
33. Hetier, E., Ayala, J., Denefle, P., Brousseau, A., Rouget, P., Mallat, M. and Prochiantz, A. (1988) Brain macrophages synthesize interleukin-1 and interleukin-1 mRNA in vitro. J. Neurosci. Res. 21, 391-397.
34. Hogquist, K., Unanue, E. and Chaplin, D. (1991) Release of IL-1 from mononuclear phagocytes. J. Immunol. 147, 2181-2186.
35. Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J.M., Masters, C.L., Grezeschik, K.H., Multhaup, G., Beyreuther, K. and Muller-Hill, B. (1987) The precursor of the Alzheimer's disease amyloid A4 protein resembles a cell surface receptor. Nature 325, 733-736.
36. Katsuki, H., Nakai, S., Hirai, Y., Akaji, K., Kiso, Y. and Satoh, M. (1990) Interleukin-1 beta inhibits long term potentiation in the CA3 region of mouse hippocampal slices. Eur. J. Pharmacol. 181, 323-326.
37. Katsuura, G., Gottschall, P.E., Dahl, R.R. and Arimura, A. (1989) Interleukin-1β increases prostaglandin E2 in rat astrocyte cultures: modulatory effect of neuropeptides. Endocrinology 124, 3125-3127.
38. Kowall, N.W. and Beal, M.F. (1988) Cortical somatostatin, neuropeptide Y and NADPH diaphorase neurons: Normal anatomy and alterations in Alzheimer's disease. Ann. Neurol. 23, 105-114.
39. Kushner, I. and Rzewnicki, D.L. (1994) The acute phase response: General aspects. Bailliere's Clin. Rheumatol. 8, 513-530.
40. Ling, E.A. (1981) The origin and nature of microglia. In: ed. S. Fedoroff and L. Hertz, Advances in Cellular Neurobiology, Vol. 2, Academic, New York, pp 33-82.
41. Lorton, D., Kocsis, J.M., King, L., Madden, K. and Brunden, K.R. (1993) β-Amyloid (25-35) enhances release of interleukin-1β (IL-1β) from activated human monocytes. Soc. Neurosci. Abstr. 19, 186.
42. Majde, J. (1988) Ca commercially available serum-free medium appropriate for studies of macrophage functions in vitro. J. Immunol. Meth. 115, 89-93.
43. Mancardi, G.L., Liwnicz, B.H. and Mandybur, T.I. (1983) Fibrous astrocytes in Alzheimer's disease and senile dementia of the Alzheimer's type. Acta Neuropathol. 61, 76-80.
44. May, L.T., Gotschall, P., Bahl, R. and Arimura, A. (1989) Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-proteins and inhibition of proliferation. Biochem. Biophys. Res. Commun. 159, 991-998.
45. McGeer, P.L., Akiyama, H., Itagaki, S. and McGeer, E.G. (1989) Activation of the classical complement pathway in brain tissue of Alzheimer patients. Neurosci. Lett. 107, 341-346.
46. McGeer, P.L., Rogers, J. and McGeer, E.G. (1994) Neuroimmune mechanisms in Alzheimer Disease pathogenesis. Alzheimer Disease Associated Disorders 8, 149-158.
47. Murrell, J., Farlow, M., Ghetti, B. and Benson, M.D. (1991) A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 254, 97-99.
48. Pasternack, J.M., Abraham, C.R., VanDyke, B.J., Potter, H. and Younkin, S.G. (1989) Astrocytes in Alzheimer's disease gray matter express α1-antichymotrypsin mRNA. Amer. J. Pathol. 135, 827-834.
49. Perry, V.H. and Gordon, S. (1988) Macrophages and microglia in the nervous system. TINS 11, 273-277.
50. Picken, M.M., Larrondo-Lillo, M., Coria, F., Gallo, G.R., Shelanski, M.L. and Frangione, B. (1990) Distribution of the protease inhibitor α1-antichymotrypsin in cerebral and systemic amyloid. J. Neuropathol. Exp. Neurol. 49, 41-48.
51. Rogers, J., Cooper, N.R., Webster, S., Schultz, J., McGeer, P.L., Styren, S.D., Civin, W.H., Brachova, L., Brandt, B., Ward, P. and Lieberburg, I. (1992) Complement activation by beta-amyloid in Alzheimer disease. Proc. Nat. Acad. Sci. USA 89, 10016-10020.
52. Rokita, H., Bartle, L. and Sipe, J.D. (1992) Differential effect of interleukin-1 on interleukin-6-stimulated alpha-1-antichymotrypsin expression in human hepatoma cell lines. Folia Histochem. Cytobiol. 30, 161-163.
53. Rozemuller, J.M., Abbink, J.J., Kamp, A.M., Stam, F.C., Hack, C.E. and Eikelenboom, P. (1991) Distribution pattern and functional state of α1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. An immunohistochemical study with monoclonal antibodies against 11 native and inactivated α-antichymotrypsin. Acta Neuropathol. 82, 200-207.
54. Selko, E.J. (1989a) Amyloid β protein precursor and the pathogenesis of Alzheimer's disease. Cell 58, 611-612.
55. Selko, E.J. (1989b) Biochemistry of altered brain proteins in Alzheimer's disease. Annu. Rev. Neurosci. 12, 463-490.
56. Selko, D. (1991) The molecular pathology of Alzheimer's disease. Neuron 6, 487-498.
57. Sievers, J., Parwaresch, R. and Wottge, H.-U. (1994) Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: morphology. Glia 12, 245-258.
58. Strauss, S., Bauer, J., Ganter, U., Jonas, U., Berger, M. and Volk, B. (1992) Detection of interleukin-6 and α2-macroglobulin immunoreactivity in cortex and hippocampus of Alzheimer's disease patients. Lab. Invest. 66, 223-229.
59. Streit, W.J., Graeber, M.B. and B.W. Krutzberg, B.W. (1988) Functional plasticity of microglia: A review. Glia 1, 301-307.
60. Thomas, W.E. (1992) Brain macrophages: Evaluation of microglia and their function. Brain Res. Rev. 17, 61-74.
61. Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y., Konno, T. and Tada, K. (1980). Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer 26, 171-176.
62. Yao, J., Harvath, L., Gilbert, D.L. and Colton, C.A. (1990) Chemotaxis by CNS macrophage, the microglia. J. Neurosci. Res. 27, 36-42.
63. Yao, J., Keri, J.E., Taffs, R.E. and Colton, C.A. (1992) Characterization of interleukin-production by microglia in culture. Brain Res. 591, 88-93.
64. Van Leeuwen, M.A. and Van Rijswijk, M.H. (1994) Acute phase proteins in the monitoring of inflammatory disorders. Baillier's Clin. Rheumatol. 8, 531-552.
65. Wang, R., Meschia, J.F., Cotter, R.J. and Sisodia, S.S. (1991) Secretion of the β/A4 amyloid precursor protein. J. Biol. Chem. 266, 16960-16964.
66. Wewers, M. and Herzyk, D. (1989) Alveolar macrophages differ from blood monocytes in human IL-1 beta release. J. Immunol. 143, 1635-1641.