Diverse approaches to combinatorial library design

Pharmacochemistry Library

Volumn 29, Issue C, 1998, Pages 133-146

  Martin, Eric J ^a   Critchlow, Roger E ^a   Spellmeyer, David C ^a   Rosenberg, Steven ^a   Spear, Kerry L ^a   Blaney, Jeffrey M ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001027207     PISSN: 01657208     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0165-7208(98)80052-4     Document Type: Chapter

References (13)

1. Martin E.J., Blaney J.M., Siani M.A., Spellmeyer D.C., Wong A.K., and Moos W.H. Measuring Diversity: Experimental Design of Combinatorial Libraries for Drug Discovery. J. Med. Chem 38 (1995) 1431-1436
2. Weininger D. Thor (1993), Daylight Chemical Information Systems, Irvine, CA
3. Weininger D. Merlin (1993), Daylight Chemical Information Systems, Irvine, CA
4. Chemical Design Ltd. Chem-X Combinatorial Chemistry User Guide, JUL 96 (1996), Jantec Printing Ltd, Oxon, England
5. Urbana, IL. Carroll D.L. GA162 v1.6.2 (1997). http://www.Staff.uiuc.edu/∼carroll/ga.html
6. Weininger D. Rubicon Reference Manual v4.51 (1997), Daylight Chemical Information Systems, Inc., Irvine, CA
7. Blaney J.M., and Dixon J.S. DGEOMDOCK (1992), Chiron Corp, Emeryville, CA
8. Jan D. rotomers (1996), Chiron Corp., Emeryville
9. Siani M. MakeSpheres (1995), Chiron Corp., Emeryville, CA
10. MDL. Available Chemicals Directory (1993), Molecular Design Limited, San Leandro, CA
11. Zuckermann R.N., Martin E.J., Spellmeyer D.C., Stauber G.B., Shoemaker K.R., Kerr J.M., Figliozzi G.M., Siani M.A., Simon R.J., Banville S.C., Brown E.G., Wang L., and Moos W.H. Discovery of Nanomolar Ligands for 7-Transmembrane G-Protein Coupled Receptors from a Diverse (N-Substituted)Glycine Peptoid Library. J. Med. Chem. 37 (1994) 2678-2685
12. Patent No. WO 9640747 A1. Rosenberg S., Spear K.L., and Martin E.J. Preparation of peptide ligands of the urokinase plasminogen activator receptor. Rosenberg, Steve; Spear, Kerry L.; Martin, Eric J.: PCT Int. Appl. (1996), Chiron Corporation, USA
13. Brandstetter H., Turk D., Hoeffken H.W., Grosse D., Stuerzebecher J., Martin P.D., Edwards B.F.P., and Bode W. Refined 2.3 Angstroms X-Ray Crystal Structure of Bovine Thrombin Complexes Formed With the Benzamidine and Arginine-Based Thrombin Inhibitors Napap, 4-Tapap and Mqpa: A Starting Point for Improving Antithrombotics. J. Mol. Biol. 226 (1992) 1085