Bifunctional alkylating agents derived from duocarmycin SA: Potent antitumor activity with altered sequence selectivity

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 5, 2000, Pages 495-498

  Boger, Dale L ^a   Searcey, Mark ^a   Tse, Winston C ^a   Jin, Qing ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG ANALOG; DUOCARMYCIN SA;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CYTOTOXICITY; DNA ALKYLATION; DRUG SELECTIVITY; DRUG SYNTHESIS; ENANTIOMER; IC 50; INHIBITION KINETICS; LEUKEMIA CELL LINE; LEUKEMIA L 1210; NONHUMAN;

ALKYLATION; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CATALYSIS; DNA; INDOLES; LEUKEMIA L1210; PYRROLES; STEREOISOMERISM;

ANIMALIA;

EID: 0034611369     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00042-1     Document Type: Article

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