Inhibitory effects of water-soluble polymers on precipitation of RS-8359

International Journal of Pharmaceutics

Volumn 154, Issue 1, 1997, Pages 59-66

  Usui, Fusao ^a,b   Maeda, Kazuko ^b   Kusai, Akira ^b   Nishimura, Kenji ^b   Yamamoto, Keiji ^a  

^a CHIBA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Hydroxypropylcellulose; Hydroxypropylmethylcellulose; Polyvinylpyrrolidone; Precipitation; RS 8359; Supersaturation

Indexed keywords

4 (4 CYANOANILINO) 6,7 DIHYDRO 7 HYDROXY 5H CYCLOPENTA[D]PYRIMIDINE; BUFFER; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; PHOSPHATE; POLYMER; POVIDONE; WATER;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SOLUBILITY; PRECIPITATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLUTION AND SOLUBILITY; VISCOSITY; X RAY DIFFRACTION;

EID: 0030805738     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00129-4     Document Type: Article

References (16)

1. Chiou, W.L., Riegelman, S., 1970. Oral Absorption of Griseofulvin in dogs: increased absorption via solid dispersion in polyethylene glycol 6000. J. Pharm. Sci. 59 (7), 937-942.
2. Chow, A.H.L., Gordon, J.D., Szeitz, A., Young, J.W.M., 1995. Modification of Phenytoin Crystals. III. Influence of 3-butanoyloxymethyl-5,5-diphenylhydantoin on solution-phase crystallization and related crystal properties. Int. J. Pharm. 126, 11-19.
3. Doherty, C., York, P., 1987. Evidence for Solid- and Liquid-State Interaction in a Furosemide-Polyvinylpyrrolidone Solid Dispersion. J. Pharm. Sci. 76 (9), 731-737.
4. Duddu, S.P., Fung, F.K.Y., Grant, D.J.W., 1996. Effects of crystallization in the presence of the opposite enantiomer on the crystal properties of (ss)-(+)-pseudoephedrinium salicylate. Int. J. Pharm. 127, 53-63.
5. Goldberg, A.H., Gibaldi, M., Kanig, J.L., 1966. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions. J. Pharm. Sci. 55 (5), 487-492.
6. Higuchi, T., Kuramoto, R., Study of possible complex formation between macromolecules and certain pharmaceuticals., J. Am. Pharm. Assoc. Sci. Ed., 47(7) 1954 393-401.
7. Loftsson, T., Fridriksdottir, H., Gudmundsdottir, T.K., 1996. The effect of water-soluble polymers on aqueous solubility of drugs. Int. J. Pharm. 127, 293-296.
8. Nielsen, A.E., Toft, J.M., 1984. Electrolyte crystal growth kinetics. J. Cryst. Growth 67, 278-288.
9. Otsuka, M., Matsuda, Y., 1995. Effects of cogrinding with various kinds of surfactants on the dissolution behavior of phenytoin. J. Pharm. Sci. 84 (12), 1434-1437.
10. Shefter, E., Higuchi, T., 1963. Dissolution behavior of crystalline solvated and nonsolvated forms of some pharmaceuticals. J. Pharm Sci. 52, 781-791.
11. Stavchansky, S., Gowan, W.G., 1984. Evaluation of the bioavailability of a solid dispersion of phenytoin in polyethylene glycol 6000 and a commercial phenytoin sodium capsule in the dog. J. Pharm. Sci. 73 (6), 733-736.
12. Suzuki, S., Miyazaki, Y., Sakurai, S., Yakou, S., Sugihara, M., 1990. Dissolution behavior of phenytoin solid dispersion. Yakuzaigaku 50 (3), 273-278.
13. Tomson, M.B., 1983. Effect of precipitation inhibitors on calcium carbonate scale formation. J. Cryst. Growth 62, 106-112.
14. Watanabe, A., Suzuki, S., Fukumori, K., 1990. Effect of casein protein on dissolution of phenytoin. Yakuzaigaku 50 (2), 172-178.
15. Yokoyama, T., Karube, T., Iwata, N., 1989. Comparative study of the effects of rs-8359 and safrazine on monoamine oxidase in-vitro and in-vivo in mouse brain. J. Pharm. Pharmacol. 41, 32-36.
16. Yonemochi, E., Oda, K., Saeki, S., Oguchi, T., Nakai, Y., Yamamoto, K., 1994. Physicochemical properties of amorphous ursodeoxycholic acid obtained by grinding. Chem. Pharm. Bull. 42 (9), 1948-1950.