Preparation, dissolution and characterization of albendazole solid dispersions

International Journal of Pharmaceutics

Volumn 140, Issue 2, 1996, Pages 247-250

  Torrado, Susana ^a,b   Torrado, Santiago ^a,b   Torrado, Juan José ^a,b   Cadórniga, Rafael ^a,b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Albendazole; Dissolution rate; Drug carrier; Polyvinylpyrrolidone; Powder X ray diffraction; Solid dispersion

Indexed keywords

ALBENDAZOLE; DRUG CARRIER; POVIDONE;

ARTICLE; DISPERSION; DISSOLUTION; DRUG SOLUBILITY; PRIORITY JOURNAL; X RAY DIFFRACTION;

EID: 0030606846     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)04586-3     Document Type: Article

References (10)

1. Cook, G.C., Use of Benzimidazole Chemotherapy in Human Helminthiases: Indications and Efficacy. Parasitol. Today, 6 (1990) 133-136.
2. Chiou, W.L. and Riegelman, S., Pharmaceutical applications of solid dispersion system. J. Pharm. Sci., 60 (1971) 1281-1302.
3. Del-Brutto, O.H., Sotelo and Roman, G.C., Therapy for neurocysticercosis: a reappraisal. Clin. Infect. Dis., 17 (1993) 730-735.
4. Jachowicz, R., Nürnberg, E. and Hoppe, R., Solid dispersions of oxazepam. Int. J. Pharm., 99 (1993) 321-325.
5. Kearney, A.S., Gabriel, D.L., Mehta, S.C. and Radebaugh, G.W., Effect of polyvinylpirrolidone on the crystallinity and dissolution rate of solid dispersions of the antiinflammatory CI 987. Int. J. Pharm., 104 (1994) 169-174.
6. Khan, K.A. and Rhodes, C.T., The concept of dissolution efficiency. Pharm. Acta Helv. 47 (1972) 594-607.
7. Sekiguchi, K. and Obi, N., Studies on absorption of eutectic mixtures I. A comparison of the behavior of eutectic mixtures of sulfathiazole and that of ordinary sulfathiazole in man. Chem. Pharm. Bull., 9 (1961) 866-872.
8. Sheu, M.T., Yeh, C.M. and Sokoloski, T.D., Characterization and dissolution of fenofibrate solid dispersion systems. Int. J. Pharm., 103 (1994) 137-146.
9. Wen, H., New, R.R.C. and Craig, P.S., Diagnosis and treatment of human hydatidosis. Br. J. Clin. Pharm., 35 (1993) 565-574.
10. Yu, X., Zipp, G.L. and Davidson, G.W.R., The effect of temperature and pH on the solubility of quinolone compounds: Estimation of heat of fusion. Pharm. Res., 11 (1994) 522-527.