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Volumn 28, Issue 6, 2000, Pages 324-337
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Rational design of pyrrolo[1,2-a]benzimidazole-based antitumor agents targeting the DNA major groove
a a a |
Author keywords
Antitumor agents; Cancer enantioselection; DNA reductive alkylation; DT diaphorase; Major groove recognition
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Indexed keywords
ANTINEOPLASTIC AGENT;
BENZIMIDAZOLE DERIVATIVE;
CARBONYL DERIVATIVE;
DIHYDROLIPOAMIDE DEHYDROGENASE;
DNA;
PYRROLO[1,2 A]BENZIMIDAZOLE;
THYMINE DERIVATIVE;
UNCLASSIFIED DRUG;
ARTICLE;
BASE PAIRING;
DNA BINDING;
DRUG DESIGN;
DRUG DNA INTERACTION;
ENANTIOMER;
GENE TARGETING;
HUMAN;
HYDROGEN BOND;
MOLECULAR MODEL;
MOLECULAR RECOGNITION;
NONHUMAN;
OVARY CANCER;
PRIORITY JOURNAL;
REDUCTION;
STEREOCHEMISTRY;
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EID: 0034452112
PISSN: 00452068
EISSN: None
Source Type: Journal
DOI: 10.1006/bioo.2000.1183 Document Type: Article |
Times cited : (19)
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References (29)
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